scholarly journals In Vitro and In Vivo Investigation of High-Intensity Focused Ultrasound (HIFU) Hat-Type Ablation Mode

2017 ◽  
Vol 23 ◽  
pp. 3373-3382 ◽  
Author(s):  
Hongya Dai ◽  
Fei Chen ◽  
Sijing Yan ◽  
Xiaoya Ding ◽  
Dazhao Ma ◽  
...  
Keyword(s):  
High Intensity ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound

In vitro and in vivo brain ablation created by high-intensity focused ultrasound and monitored by MRI

2009 ◽  
Vol 56 (6) ◽  
pp. 1189-1198 ◽  
Author(s):  
C. Damianou ◽  
K. Ioannides ◽  
V. Hadjisavvas ◽  
N. Mylonas ◽  
A. Couppis ◽  
...  
Keyword(s):  
High Intensity ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound

scholarly journals Magnetic resonance–guided, high-intensity focused ultrasound sonolysis: potential applications for stroke

2018 ◽  
Vol 44 (2) ◽  
pp. E12 ◽  
Author(s):  
Adeel Ilyas ◽  
Ching-Jen Chen ◽  
Dale Ding ◽  
Andrew Romeo ◽  
Thomas J. Buell ◽  
...  
Keyword(s):  
High Intensity ◽  
Focused Ultrasound ◽  
Therapeutic Option ◽  
High Intensity Focused Ultrasound ◽  
Clot Lysis ◽  
Vessel Occlusion ◽  
Technological Advances ◽  
Stroke Models

Stroke is one of the leading causes of death worldwide and a significant source of long-term morbidity. Unfortunately, a substantial number of stroke patients either are ineligible or do not significantly benefit from contemporary medical and interventional therapies. To address this void, investigators recently made technological advances to render transcranial MR-guided, high-intensity focused ultrasound (MRg-HIFU) sonolysis a potential therapeutic option for both acute ischemic stroke (AIS)—as an alternative for patients with emergent large-vessel occlusion (ELVO) who are ineligible for endovascular mechanical thrombectomy (EMT) or as salvage therapy for patients in whom EMT fails—and intracerebral hemorrhage (ICH)—as a neoadjuvant means of clot lysis prior to surgical evacuation. Herein, the authors review the technological principles behind MRg-HIFU sonolysis, its results in in vitro and in vivo stroke models, and its potential clinical applications. As a noninvasive transcranial technique that affords rapid clot lysis, MRg-HIFU thrombolysis may develop into a therapeutic option for patients with AIS or ICH. However, additional studies of transcranial MRg-HIFU are necessary to ascertain the merit of this treatment approach for thrombolysis in both AIS and ICH, as well as its technical limitations and risks.

scholarly journals In Vitro and In Vivo High-Intensity Focused Ultrasound Thrombolysis

2012 ◽  
Vol 47 (4) ◽  
pp. 217-225 ◽  
Author(s):  
Cameron Wright ◽  
Kullervo Hynynen ◽  
David Goertz
Keyword(s):  
High Intensity ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound
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