scholarly journals White and Gray Matter Volume Changes and Correlation with Visual Evoked Potential in Patients with Optic Neuritis: A Voxel-Based Morphometry Study

2016 ◽  
Vol 22 ◽  
pp. 1115-1123 ◽  
Author(s):  
Xin Huang ◽  
Qiang Zhang ◽  
Pei-Hong Hu ◽  
Yu-Lin Zhong ◽  
Ying Zhang ◽  
...  
Keyword(s):  
Optic Neuritis ◽  
Gray Matter ◽  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Gray Matter Volume ◽  
Voxel Based Morphometry ◽  
Volume Changes ◽  
Matter Volume ◽  
Visual Evoked

Reproducibility of Brain Volume Changes in Longitudinal Voxel-Based Morphometry Between Non-Accelerated and Accelerated Magnetic Resonance Imaging

2021 ◽  
pp. 1-10
Author(s):  
Hidemasa Takao ◽  
Shiori Amemiya ◽  
Osamu Abe ◽  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Magnetic Resonance ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Elderly Subjects ◽  
Voxel Based Morphometry ◽  
Volume Changes ◽  
Matter Volume ◽  
Healthy Elderly

Background: Scan acceleration techniques, such as parallel imaging, can reduce scan times, but reliability is essential to implement these techniques in neuroimaging. Objective: To evaluate the reproducibility of the longitudinal changes in brain morphology determined by longitudinal voxel-based morphometry (VBM) between non-accelerated and accelerated magnetic resonance images (MRI) in normal aging, mild cognitive impairment (MCI), and Alzheimer’s disease (AD). Methods: Using data from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) 2 database, comprising subjects who underwent non-accelerated and accelerated structural T1-weighted MRI at screening and at a 2-year follow-up on 3.0 T Philips scanners, we examined the reproducibility of longitudinal gray matter volume changes determined by longitudinal VBM processing between non-accelerated and accelerated imaging in 50 healthy elderly subjects, 54 MCI patients, and eight AD patients. Results: The intraclass correlation coefficient (ICC) maps differed among the three groups. The mean ICC was 0.72 overall (healthy elderly, 0.63; MCI, 0.75; AD, 0.63), and the ICC was good to excellent (0.6–1.0) for 81.4%of voxels (healthy elderly, 64.8%; MCI, 85.0%; AD, 65.0%). The differences in image quality (head motion) were not significant (Kruskal–Wallis test, p = 0.18) and the within-subject standard deviations of longitudinal gray matter volume changes were similar among the groups. Conclusion: The results indicate that the reproducibility of longitudinal gray matter volume changes determined by VBM between non-accelerated and accelerated MRI is good to excellent for many regions but may vary between diseases and regions.

scholarly journals Voxel-based morphometry reveals brain gray matter volume changes in successful dieters

Obesity ◽  
2016 ◽  
Vol 24 (9) ◽  
pp. 1842-1848 ◽  
Author(s):  
Robyn A. Honea ◽  
Amanda N. Szabo-Reed ◽  
Rebecca J. Lepping ◽  
Rodrigo Perea ◽  
Florence Breslin ◽  
...  
Keyword(s):  
Gray Matter ◽  
Gray Matter Volume ◽  
Voxel Based Morphometry ◽  
Volume Changes ◽  
Matter Volume

scholarly journals Gray Matter Volume Changes in Patients With Acute Eye Pain: A Voxel-Based Morphometry Study

2019 ◽  
Vol 8 (1) ◽  
pp. 1 ◽  
Author(s):  
Dong-Yi Lan ◽  
Pei-Wen Zhu ◽  
Ying He ◽  
Qian-Hui Xu ◽  
Ting Su ◽  
...  
Keyword(s):  
Gray Matter ◽  
Gray Matter Volume ◽  
Voxel Based Morphometry ◽  
Volume Changes ◽  
Matter Volume ◽  
Eye Pain

scholarly journals Clinical Features and Visual outcome in Acute and Recurrent Case of Optic Neuritis.

2018 ◽  
Vol 1 (01) ◽  
pp. 56-63
Author(s):  
Jyoti Bastola Paudel ◽  
Ananda Kumar Sharma ◽  
Sanjeeta Sitaula ◽  
Madhu Thapa
Keyword(s):  
Multiple Sclerosis ◽  
Natural History ◽  
Optic Neuritis ◽  
Clinical Features ◽  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Oral Steroid ◽  
Visual Recovery ◽  
Visual Evoked

Introduction: Optic neuritis is an inflammation of the optic nerve that usually affects young females. In Western countries, natural history and treatment of optic neuritis(ON) has been studied extensively. However aetiology, natural history, clinical features of ON and their relation to multiple sclerosis in Asian population needs to be defined yet. Methods: 30 patients who were diagnosed as optic neuritis were included between June 2013 to December 2014 at BP Koirala Lions Centre for Ophthalmic Studies (BPKLCOS). A detailed history was obtained followed by examination of anterior and posterior segment. Assessment of visual acuity, color vision, contrast sensitivity, visual evoked potential (VEP),visual field and MRI of orbit and brain was done in all cases. All patients were treated with intravenous Methylprednisolone 500mg twice daily for 3 days followed by oral steroid for 11 days which was tapered in the next 4 days.The patients were reassessed at 2 weeks, 1 month and 3months. Results: Commonest presenting symptom was diminution of vision(65%). MRI showed multiple paraventricular oval plaques definite of multiple sclerosis in one patient and one was diagnosed as probable MS who had a single periventricular plaque. Visual evoked potential (VEP) showed increase in the mean P100 latency at 60’ and reduction in amplitude in eyes affected with optic neuritis compared to normal eyes. At 3 months follow up, 70% had good visual recovery (>6/18). The cause of non-improvement in vision was disc pallor. Optic disc pallor was detected in 37.5% of the eyes during follow up. Conclusions: Good visual recovery was observed in most eyes with acute optic neuritis. Multiple sclerosis was seen in 1 patient who had recurrent optic neuritis.

scholarly journals Is Gray Matter Volume an Intermediate Phenotype for Schizophrenia? A Voxel-Based Morphometry Study of Patients with Schizophrenia and Their Healthy Siblings

2008 ◽  
Vol 63 (5) ◽  
pp. 465-474 ◽  
Author(s):  
Robyn A. Honea ◽  
Andreas Meyer-Lindenberg ◽  
Katherine B. Hobbs ◽  
Lukas Pezawas ◽  
Venkata S. Mattay ◽  
...  
Keyword(s):  
Gray Matter ◽  
Gray Matter Volume ◽  
Intermediate Phenotype ◽  
Voxel Based Morphometry ◽  
Matter Volume ◽  
Healthy Siblings

Putaminal gray matter volume decrease in panic disorder: an optimized voxel-based morphometry study

2005 ◽  
Vol 22 (8) ◽  
pp. 2089-2094 ◽  
Author(s):  
Hanik K. Yoo ◽  
Minue J. Kim ◽  
Seog Ju Kim ◽  
Young Hoon Sung ◽  
Minyoung E. Sim ◽  
...  
Keyword(s):  
Panic Disorder ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Voxel Based Morphometry ◽  
Matter Volume ◽  
Volume Decrease

scholarly journals The Gray Matter Volume of the Amygdala Is Correlated with the Perception of Melodic Intervals: A Voxel-Based Morphometry Study

PLoS ONE ◽  
2014 ◽  
Vol 9 (6) ◽  
pp. e99889 ◽  
Author(s):  
Xueting Li ◽  
Alain De Beuckelaer ◽  
Jiahui Guo ◽  
Feilong Ma ◽  
Miao Xu ◽  
...  
Keyword(s):  
Gray Matter ◽  
Gray Matter Volume ◽  
Voxel Based Morphometry ◽  
Matter Volume

Effects of cumulative illness severity on hippocampal gray matter volume in major depression: a voxel-based morphometry study

2018 ◽  
Vol 48 (14) ◽  
pp. 2391-2398 ◽  
Author(s):  
Dario Zaremba ◽  
Verena Enneking ◽  
Susanne Meinert ◽  
Katharina Förster ◽  
Christian Bürger ◽  
...  
Keyword(s):  
Major Depression ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Principal Component ◽  
Hippocampal Volume ◽  
Illness Severity ◽  
Voxel Based Morphometry ◽  
Matter Volume ◽  
Duration Of Illness ◽  
Component Scores

AbstractBackgroundPatients with major depression show reduced hippocampal volume compared to healthy controls. However, the contribution of patients’ cumulative illness severity to hippocampal volume has rarely been investigated. It was the aim of our study to find a composite score of cumulative illness severity that is associated with hippocampal volume in depression.MethodsWe estimated hippocampal gray matter volume using 3-tesla brain magnetic resonance imaging in 213 inpatients with acute major depression according to DSM-IV criteria (employing the SCID interview) and 213 healthy controls. Patients’ cumulative illness severity was ascertained by six clinical variables via structured clinical interviews. A principal component analysis was conducted to identify components reflecting cumulative illness severity. Regression analyses and a voxel-based morphometry approach were used to investigate the influence of patients’ individual component scores on hippocampal volume.ResultsPrincipal component analysis yielded two main components of cumulative illness severity: Hospitalization and Duration of Illness. While the component Hospitalization incorporated information from the intensity of inpatient treatment, the component Duration of Illness was based on the duration and frequency of illness episodes. We could demonstrate a significant inverse association of patients’ Hospitalization component scores with bilateral hippocampal gray matter volume. This relationship was not found for Duration of Illness component scores.ConclusionsVariables associated with patients’ history of psychiatric hospitalization seem to be accurate predictors of hippocampal volume in major depression and reliable estimators of patients’ cumulative illness severity. Future studies should pay attention to these measures when investigating hippocampal volume changes in major depression.

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