scholarly journals Diethylstilbestrol Regulates the Expression of LGR8 in Mouse Gubernaculum Testis Cells

2016 ◽  
Vol 22 ◽  
pp. 416-421
Author(s):  
Shouxing Duan ◽  
Xuewu Jiang ◽  
Xuan Zhang ◽  
Lei Xie ◽  
Zongbo Sun ◽  
...  
Keyword(s):  
Gubernaculum Testis

STUDY OF GUBERNACULUM TESTIS IN HUMAN FETUSES AND IN CRYPTORCHIDISM

2003 ◽  
Vol 26 (2) ◽  
pp. 131-149
Author(s):  
Azza Hussien ◽  
Nadia EI Rouby ◽  
Ashraf Kabesh
Keyword(s):  
Human Fetuses ◽  
Gubernaculum Testis

Embryonal Renal Remnant in the Gubernaculum Testis

1999 ◽  
Vol 9 (03) ◽  
pp. 186-188 ◽  
Author(s):  
K. Yoshida ◽  
K. Ohama ◽  
K. Tsuchida ◽  
H. Minato ◽  
H. Kurumaya
Keyword(s):  
Gubernaculum Testis

446 Structural study of gubernaculum testis in fetuses with Prune Belly Syndrome

2014 ◽  
Vol 13 (1) ◽  
pp. e446
Author(s):  
Costa S. Freitas ◽  
Costa W. Silva ◽  
F.J. Sampaio ◽  
L.A. Favorito
Keyword(s):  
Structural Study ◽  
Prune Belly Syndrome ◽  
Prune Belly ◽  
Gubernaculum Testis

Testicular Migration: Remodeling of Connective Tissue and Muscle Cells in Human Gubernaculum Testis

2002 ◽  
pp. 2171-2176 ◽  
Author(s):  
WALDEMAR S. COSTA ◽  
FRANCISCO J. B. SAMPAIO ◽  
LUCIANO A. FAVORITO ◽  
LUIZ E. M. CARDOSO
Keyword(s):  
Connective Tissue ◽  
Muscle Cells ◽  
Testicular Migration ◽  
Gubernaculum Testis

An insight into testis and gubernaculum dynamics of INSL3 - RXFP2 signalling during testicular descent in the dog

2010 ◽  
Vol 22 (5) ◽  
pp. 751 ◽  
Author(s):  
S. Arrighi ◽  
G. Bosi ◽  
D. Groppetti ◽  
M. Aralla ◽  
F. Cremonesi
Keyword(s):  
Sertoli Cells ◽  
Leydig Cells ◽  
Feedback Loop ◽  
Testicular Descent ◽  
Fetal Period ◽  
Male Development ◽  
Dog Testis ◽  
Gubernaculum Testis ◽  
Insight Into ◽  
Different Tissues

Insulin-like 3 (INSL3) plays a prominent role in male development and is supposed to induce the growth of the gubernaculum testis (g.t.), thus being directly involved in testicular descent in humans and rodents. This happens through activation of the RXFP2 receptor (GREAT or LGR8). The INSL3–RXFP2 complex is reputed to play an additional paracrine role in the testis, possibly acting as part of an autocrine feedback loop. The present work provides evidence of the immunolocalisation of INSL3 in the Leydig cells of canine fetuses and of the expression of RXFP2 receptor in different tissues of the g.t. of the same specimens. RXFP2 was localised at the cell membrane of g.t. muscle and connective cells, as well as in the epithelial cells of the developing excurrent ducts. Notably, RXFP2 immunoreactivity of the g.t. was limited to fetuses at ~35–45 days of gestation, which is also the fetal period when the endocrine compartment of the dog testis is active endocrinologically, as confirmed by the anti-P450c17 and anti-INSL3 immunoreactivities of the fetal Leydig cells, and by anti-Müllerian hormone immunoreactivity of the Sertoli cells. The same immunoreactivities were also evaluated in the testes of cryptorchid dogs of different ages. RXFP2 immunoreactivity was absent from genital tracts of cryptorchid testes and g.t. remnants.

scholarly journals Left-sided cryptorchidism in mice with Wilms' tumour 1 gene deletion in gubernaculum testis

2013 ◽  
Vol 230 (1) ◽  
pp. 39-47 ◽  
Author(s):  
Elena M Kaftanovskaya ◽  
Giselle Neukirchner ◽  
Vicki Huff ◽  
Alexander I Agoulnik
Keyword(s):  
Gene Deletion ◽  
Wilms Tumour ◽  
Gubernaculum Testis

Diethylstilbestrol regulates mouse gubernaculum testis cell proliferation via PLC-Ca2+ -CREB pathway

2017 ◽  
Vol 36 (1) ◽  
pp. 13-17 ◽  
Author(s):  
Xuan Zhang ◽  
Hong-yan Ping ◽  
Jian-hong Li ◽  
Shou-xin Duan ◽  
Xue-wu Jiang
Keyword(s):  
Cell Proliferation ◽  
Gubernaculum Testis ◽  
Creb Pathway
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