scholarly journals Preparation of Calcium Phosphate Cement and Polymethyl Methacrylate for Biological Composite Bone Cements

2015 ◽  
Vol 21 ◽  
pp. 1162-1172 ◽  
Author(s):  
Bin Yu
Author(s):  
Nuan La Ong Srakaew ◽  
Sirirat Tubsungnoen Rattanachan

Self-setting calcium phosphate cement (CPC) has been used in bone repair and substitution due to their excellent biocompatibility, bioactive as well as simplicity of preparation and use. The inherent brittleness and slow degradation are the major disadvantages for the use of calcium phosphate cements. To improve the degradation for the traditional CPC, the apatite cement formula incorporated with β-tricalcium phosphate (β-TCP) with varying concentration were studied and the effect of the pH value of liquid phase on the properties of this new calcium phosphate cement formula was evaluated. The apatite cements containing β-TCP for 10 and 40 wt.% were mixed into the aqueous solution with different pH values and then aging in absolute humidity at 37°C for 7 days. The setting time and phase analysis of the biphasic calcium phosphate were determined as compared to the apatite cement. For proper medical application, the compressive strength, the phase analysis and the degradation of the CPC samples at pH 7.0 and 7.4 were evaluated after soaking in the simulated body fluid (SBF) at 37°C for 7 days. The results indicated that the properties of the samples such as the setting time, the compressive strength related to the phase analysis of the set cements. The high degradation of the CPC was found in the cement with increasing β-TCP addition due to the phase after setting. Apatite formation with oriented plate-like morphology was also found to be denser on the surface of the biphasic bone cements after soaking in SBF for 7 days. The obtained results indicated that the cement containing β-TCP mixed with the liquid phase at pH 7.4 could be considered as a highly biodegradable and bioactive bone cement, as compared to the traditional CPC.


2011 ◽  
Vol 24 (4) ◽  
pp. 276-279 ◽  
Author(s):  
Woojin Cho ◽  
Chunhui Wu ◽  
Xiujun Zheng ◽  
Serkan Erkan ◽  
Sanjeev J. Suratwala ◽  
...  

RSC Advances ◽  
2016 ◽  
Vol 6 (1) ◽  
pp. 586-596 ◽  
Author(s):  
Miao Sun ◽  
An Liu ◽  
Chiyuan Ma ◽  
Huifeng Shao ◽  
Menghua Yu ◽  
...  

Herein we systematically investigated the biological performance of a β-dicalcium silicate (β-C2S)-based bone cement in comparison with the clinically used calcium phosphate cement (CPC) and Bio-Oss®.


Spine ◽  
2006 ◽  
Vol 31 (25) ◽  
pp. 2934-2941 ◽  
Author(s):  
Hans-Joachim Wilke ◽  
Ulrich Mehnert ◽  
Lutz E. Claes ◽  
Michael M. Bierschneider ◽  
Hans Jaksche ◽  
...  

Author(s):  
Denton D. Weiss ◽  
Matthew A. Sachs ◽  
Charles R. Woodard

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