scholarly journals Facial and Cochlear Nerve Complications following Microsurgical Resection of Vestibular Schwannomas in a Series of 221 Cases

2015 ◽  
Vol 21 ◽  
pp. 1674-1678 ◽  
Author(s):  
Yan Jiang
Keyword(s):  
Cochlear Nerve ◽  
Vestibular Schwannomas ◽  
Microsurgical Resection

Microsurgical Resection of Vestibular Schwannomas, Presentation of Cases in 3D: 3-Dimensional Operative Video

2019 ◽  
Vol 19 (1) ◽  
pp. E61-E62
Author(s):  
Alvaro Campero ◽  
Matias Baldoncini
Keyword(s):  
Facial Nerve ◽  
Cochlear Nerve ◽  
Vestibular Schwannomas ◽  
Benign Tumors ◽  
3 Dimensional ◽  
Microsurgical Resection ◽  
Magnetic Resonance Imaging Mri ◽  
The Right ◽  
Functional Preservation

Abstract Vestibular schwannomas are the most common benign tumors of the pontocerebellar angle,1,2 their microsurgical complexity is related to their size and neurovascular relationships. The purpose of this work is to analyze the clinical, anatomic characteristics, microsurgical treatment, and the postoperative results according to the Hannover gradual scale in 4 patients with vestibular schwannomas. The 4 patients gave their consent to the procedure and all consented to the use of their surgical videos, preoperative and postoperative studies, and postoperative pictures. Case 1: A 39-yr-old woman, with left ear hearing loss. Magnetic resonance imaging (MRI) showed small Intracanalicular schwannoma (T1 classification by Hannover). Microsurgery was performed and resection through a retrosigmoid approach2,3 with anatomic and functional preservation of the facial and cochlear nerve. Case 2: A 40-yr-old woman, with left ear hypoacusia. MRI showed an extrameatal schwannoma reaching the brainstem (T3b Hannover classification). The complete re-section through retrosigmoid approach were performed. Case 3: A 69-yr-old woman, without hearing in the right ear. RM: Medium schwannoma (T4a classification of Hannover). Microsurgery was performed with anatomic and functional preservation of the facial nerve.4-6 Case 4: A 32-yr-old woman, without hearing in the left ear. In addition, cerebellar syndrome and headache. RM: Large schwannoma (T4b classification of Hannover). Sur-gery was performed, anatomic preservation of the facial nerve, with moderate paresis in the postoperative period. Microsurgical resection with functional preservation of the facial and cochlear nerve is the main objective7 when addressing this pathology.

scholarly journals Understanding the Radiobiology of Vestibular Schwannomas to Overcome Radiation Resistance

Cancers ◽  
2021 ◽  
Vol 13 (18) ◽  
pp. 4575
Author(s):  
Torin P. Thielhelm ◽  
Stefania Goncalves ◽  
Scott M. Welford ◽  
Eric A. Mellon ◽  
Erin R. Cohen ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Current Knowledge ◽  
Vestibular Schwannomas ◽  
Benign Tumors ◽  
Intracranial Tumors ◽  
Treatment Protocols ◽  
Cycle Arrest ◽  
Microsurgical Resection ◽  
Cranial Nerve Viii ◽  
Key Events

Vestibular schwannomas (VS) are benign tumors arising from cranial nerve VIII that account for 8–10% of all intracranial tumors and are the most common tumors of the cerebellopontine angle. These tumors are typically managed with observation, radiation therapy, or microsurgical resection. Of the VS that are irradiated, there is a subset of tumors that are radioresistant and continue to grow; the mechanisms behind this phenomenon are not fully understood. In this review, the authors summarize how radiation causes cellular and DNA injury that can activate (1) checkpoints in the cell cycle to initiate cell cycle arrest and DNA repair and (2) key events that lead to cell death. In addition, we discuss the current knowledge of VS radiobiology and how it may contribute to clinical outcomes. A better understanding of VS radiobiology can help optimize existing treatment protocols and lead to new therapies to overcome radioresistance.

Unilateral Hearing Loss Due to Cochlear Nerve Involvement as Isolated Symptom of a Primary Medulloblastoma

2019 ◽  
Vol 51 (02) ◽  
pp. 170-172
Author(s):  
Janine Magg ◽  
Thomas Nägele ◽  
Michael Alber ◽  
Annette Weichselbaum ◽  
Martin Ebinger ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Pediatric Population ◽  
Wnt Signaling Pathway ◽  
Neurofibromatosis Type ◽  
Cochlear Nerve ◽  
Vestibular Schwannomas ◽  
Clinical Feature ◽  
Unilateral Hearing Loss ◽  
Common Symptom ◽  
The Central Nervous System

AbstractUnilateral sensorineural hearing loss is a common symptom of vestibular schwannomas in adolescent patients with neurofibromatosis type 2 or sporadic vestibular schwannomas and is often the initial clinical feature. While rare cases of sensorineural impairment presenting as vision or hearing loss due to metastatic medulloblastoma are known, hearing loss as an isolated presenting symptom of primary malignant neuroepithelial tumors of the central nervous system has not been reported in the pediatric population so far. We present two adolescents with unilateral hearing loss due to cochlear nerve dysfunction as the only symptom of a primary nonmetastatic medulloblastoma of the WNT signaling pathway family members subgroup.

Microsurgical resection of vestibular schwannomas: complication avoidance

2016 ◽  
Vol 130 (2) ◽  
pp. 367-375 ◽  
Author(s):  
Shervin Rahimpour ◽  
Allan H. Friedman ◽  
Takanori Fukushima ◽  
Ali R. Zomorodi
Keyword(s):  
Vestibular Schwannomas ◽  
Microsurgical Resection

Long-Term Effects of Cerebellar Retraction in the Microsurgical Resection of Vestibular Schwannomas

2004 ◽  
Vol 114 (2) ◽  
pp. 323-326 ◽  
Author(s):  
Harold H. Kim ◽  
Ross Johnston ◽  
Richard J. Wiet ◽  
Arvind Kumar
Keyword(s):  
Vestibular Schwannomas ◽  
Long Term Effects ◽  
Cerebellar Retraction ◽  
Microsurgical Resection

The Direct Costs of Microsurgical Resection of Vestibular Schwannomas

2020 ◽  
Vol 41 (3) ◽  
pp. 397-402
Author(s):  
Joe Saliba ◽  
Amir Mohammadzadeh ◽  
Kareem O. Tawfik ◽  
Junie S. Carriere ◽  
Marc S. Schwartz ◽  
...  
Keyword(s):  
Direct Costs ◽  
Vestibular Schwannomas ◽  
Microsurgical Resection

Outcomes of Initial Observation Versus Upfront Microsurgical Resection for Small to Medium-sized Vestibular Schwannomas

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Ankita Patro ◽  
Douglas J. Totten ◽  
Alexander D. Sherry ◽  
Nauman F. Manzoor ◽  
Nathan D. Cass ◽  
...  
Keyword(s):  
Vestibular Schwannomas ◽  
Initial Observation ◽  
Microsurgical Resection

Hearing preservation in medial vestibular schwannomas

2008 ◽  
Vol 109 (1) ◽  
pp. 70-76 ◽  
Author(s):  
Christian Strauss ◽  
Barbara Bischoff ◽  
Johann Romstöck ◽  
Jens Rachinger ◽  
Stefan Rampp ◽  
...  
Keyword(s):  
Growth Pattern ◽  
Auditory Evoked Potentials ◽  
Internal Auditory Canal ◽  
Hearing Preservation ◽  
Neck Surgery ◽  
Underlying Disease ◽  
Cochlear Nerve ◽  
Vestibular Schwannomas ◽  
Consecutive Series ◽  
Tumor Removal

Object Vestibular schwannomas (VSs) with no or little extension into the internal auditory canal have been addressed as a clinical subentity carrying a poor prognosis regarding hearing preservation, which is attributed to the initially asymptomatic intracisternal growth pattern. The goal in this study was to assess hearing preservation in patients who underwent surgery for medial VSs. Methods A consecutive series of 31 cases in 30 patients with medial VSs (mean size 31 mm) who underwent surgery between 1997 and 2005 via a suboccipitolateral route was evaluated with respect to pre- and postoperative cochlear nerve function, extent of tumor removal, and radiological findings. Intraoperative monitoring of brainstem auditory evoked potentials was performed in all patients with hearing. Patients were reevaluated at a mean of 30 months following surgery. Results Preoperative hearing function revealed American Academy of Otolaryngology–Head and Neck Surgery Foundation Classes A and B in 7 patients each, Class C in 4, and D in 9. Four patients presented with deafness. Hearing preservation was achieved in 10 patients (Classes A–C in 2 patients each, and Class D in 4 patients). Tumor removal was complete in all patients with hearing preservation, except for 2 patients with neurofibromatosis. In 4 patients a planned subtotal excision was performed due to the individual's age or underlying disease. In 1 patient a recurrent tumor was completely removed 3 years after the initial procedure. Conclusions The cochlear nerve in medial VSs requires special attention due to the atypical intracisternal growth pattern. Even in large tumors, hearing could be preserved in 37% of cases, since the cochlear nerve in medial schwannomas may not exhibit the adherence to the tumor capsule seen in tumors with comparable size involving the internal auditory canal.

Microsurgical results with large vestibular schwannomas with preservation of facial and cochlear nerve function as the primary aim

2005 ◽  
Vol 147 (7) ◽  
pp. 697-706 ◽  
Author(s):  
C. Raftopoulos ◽  
B. Abu Serieh ◽  
T. Duprez ◽  
M. A. Docquier ◽  
J. M. Guérit
Keyword(s):  
Cochlear Nerve ◽  
Vestibular Schwannomas ◽  
Nerve Function

scholarly journals Microsurgical resection of an intravestibular schwannoma: a review of surgical technique and management considerations

2021 ◽  
Vol 5 (2) ◽  
pp. V6
Author(s):  
Ramin A. Morshed ◽  
Alexander F. Haddad ◽  
Kunal P. Raygor ◽  
Mary Jue Xu ◽  
Charles J. Limb ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Surgical Technique ◽  
Vestibular Schwannomas ◽  
Link Type ◽  
Rare Tumors ◽  
Microsurgical Resection ◽  
Vestibular Symptoms

Intravestibular schwannomas are rare tumors within the intralabyrinthine region and involve different management considerations compared to more common vestibular schwannomas. In this report, the authors review a case of a 52-year-old woman who presented with hearing loss and vestibular symptoms and was found to have a left intravestibular schwannoma. Given her debilitating vestibular symptoms, she underwent microsurgical resection. In this video, the authors review the relevant anatomy, surgical technique, and management considerations in these patients. The video can be found here: https://stream.cadmore.media/r10.3171/2021.7.FOCVID2187

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