scholarly journals Statistical agreement of left ventricle measurements using cardiac magnetic resonance and 2D echocardiography in ischemic heart failure

2012 ◽  
Vol 18 (3) ◽  
pp. MT19-MT25 ◽  
Author(s):  
Katarzyna Gruszczyńska ◽  
Łukasz J. Krzych ◽  
Krzysztof S. Gołba ◽  
Jolanta Biernat ◽  
Tomasz Roleder ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cardiac Magnetic Resonance ◽  
Magnetic Resonance ◽  
Left Ventricle ◽  
Ischemic Heart ◽  
Ischemic Heart Failure ◽  
2D Echocardiography

scholarly journals Functional Recovery after Intramyocardial Injection of Adipose-Derived Stromal Cells Assessed by Cardiac Magnetic Resonance Imaging

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Janusz Konstanty-Kalandyk ◽  
Jerzy Sadowski ◽  
Anna Kędziora ◽  
Małgorzata Urbańczyk-Zawadzka ◽  
Jakub Baran ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cardiac Magnetic Resonance ◽  
Magnetic Resonance ◽  
Stromal Cells ◽  
Stromal Cell ◽  
Ischemic Heart ◽  
Ischemic Heart Failure ◽  
Intramyocardial Injection ◽  
Adipose Derived Stromal Cells ◽  
Cell Implantation

Aims. A major clinical concern is the continuous increase in the number of patients diagnosed with advanced coronary artery disease, ischemic heart failure, and refractory angina, and one of the most promising treatment options for these conditions is stem cell-based therapy. The aim of this study was to assess the functional improvement following intramyocardial injection of adipose-derived stromal cells, using cardiac magnetic resonance. Methods and Results. Thirteen patients with ischemic heart failure, reduced left ventricular ejection fraction, refractory angina, and who have been disqualified from any form of direct revascularization were enrolled in the study with transthoracic autologous adipose-derived stromal cell implantation. All patients underwent cardiac magnetic resonance prior to the procedure and after 12 months of follow-up. A significant increase in stroke volume ( 83.1 ± 8.5   mL vs 93.8 ± 13.8   mL , p = 0.025 ) and stroke volume index ( 43.3 ± 7.6   mL / m 2 vs 48.7 ± 9.1   mL / m 2 , p = 0.019 ), a statistical trend toward an increase in left ventricle ejection fraction ( 36.7 ± 13.2 vs 39.7 ± 14.9 , p = 0.052 ), and cardiac output improvement ( 5.0 ± 0.7 vs 5.5 ± 0.9 , p = 0.073 ) was observed in the patient postprocedure. Enhanced relative regional thickening was noted in the segments with adipose-derived stromal cell implantation. Conclusions. Intramyocardial adipose-derived stromal cell implantation is a promising therapeutic option for selected, symptomatic patients with ischemic heart failure, who have preserved myocardial viability despite being unsuitable for direct revascularization.

scholarly journals Left ventricular noncompaction—a rare cause of triad: heart failure, ventricular arrhythmias, and systemic embolic events: a case report 

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Despina Toader ◽  
Alina Paraschiv ◽  
Petrișor Tudorașcu ◽  
Diana Tudorașcu ◽  
Constantin Bataiosu ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cardiac Magnetic Resonance ◽  
Magnetic Resonance ◽  
Left Ventricle ◽  
Ventricular Arrhythmias ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Left Ventricular Noncompaction ◽  
Ventricular Noncompaction ◽  
The Right

Abstract Background Left ventricular noncompaction is a rare cardiomyopathy characterized by a thin, compacted epicardial layer and a noncompacted endocardial layer, with trabeculations and recesses that communicate with the left ventricular cavity. In the advanced stage of the disease, the classical triad of heart failure, ventricular arrhythmia, and systemic embolization is common. Segments involved are the apex and mid inferior and lateral walls. The right ventricular apex may be affected as well. Case presentation A 29-year-old Caucasian male was hospitalized with dyspnea and fatigue at minimal exertion during the last months before admission. He also described a history of edema of the legs and abdominal pain in the last weeks. Physical examination revealed dyspnea, pulmonary rales, cardiomegaly, hepatomegaly, and splenomegaly. Electrocardiography showed sinus rhythm with nonspecific repolarization changes. Twenty-four-hour Holter monitoring identified ventricular tachycardia episodes with right bundle branch block morphology. Transthoracic echocardiography at admission revealed dilated left ventricle with trabeculations located predominantly at the apex but also in the apical and mid portion of lateral and inferior wall; end-systolic ratio of noncompacted to compacted layers > 2; moderate mitral regurgitation; and reduced left ventricular ejection fraction. Between apical trabeculations, multiple thrombi were found. The right ventricle had normal morphology and function. Speckle-tracking echocardiography also revealed systolic left ventricle dysfunction and solid body rotation. Abdominal echocardiography showed hepatomegaly and splenomegaly. Abdominal computed tomography was suggestive for hepatic and renal infarctions. Laboratory tests revealed high levels of N-terminal pro-brain natriuretic peptide and liver enzymes. Cardiac magnetic resonance evaluation at 1 month after discharge confirmed the diagnosis. The patient received anticoagulants, antiarrhythmics, and heart failure treatment. After 2 months, before device implantation, he presented clinical improvement, and echocardiographic evaluation did not detect thrombi in the left ventricle. Coronary angiography was within normal range. A cardioverter defibrillator was implanted for prevention of sudden cardiac death. Conclusions Left ventricular noncompaction is rare cardiomyopathy, but it should always be considered as a possible diagnosis in a patient hospitalized with heart failure, ventricular arrhythmias, and systemic embolic events. Echocardiography and cardiac magnetic resonance are essential imaging tools for diagnosis and follow-up.

scholarly journals Left ventricular hypertrabeculation in Ebstein anomaly – a clinically significant or irrelevant problem?

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
A Cieplucha ◽  
O Trojnarska ◽  
J Rajewska-Tabor ◽  
A Katarzynska-Szymanska ◽  
P Mitkowski ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cardiac Magnetic Resonance ◽  
Magnetic Resonance ◽  
Left Ventricle ◽  
Left Ventricular ◽  
Peak Oxygen Consumption ◽  
Ebstein Anomaly ◽  
Funding Sources ◽  
Peak Vo2 ◽  
And Function

Abstract Background Ebstein anomaly (EA) is characterized by anomalous tricuspid valve resulting in the whole right heart's distorted anatomy. Heart failure is the most frequent complication in adults with EA. Recently more attention is also paid to the left ventricle. Some limited echocardiographic data suggest a markedly increased occurrence of the left ventricular hypertrabeculation, by some authors called a non-compacted myocardium. Currently, cardiac magnetic resonance (CMR) is a gold standard in the evaluation of hypertrabeculation. However, different diagnostic criteria and discrepancies in the study outcomes make the clinical interpretation of this phenomenon questionable and challenging. Purpose To determine the frequency of the left ventricular hypertrabeculation among adults with EA; to assess its association with the ventricular size and function and the markers of heart failure. Methods Study group consisted of 35 unoperated adults (mean age 41.9±14.8 years) with Ebstein anomaly. The study protocol included: a) cardiac magnetic resonance (CMR) with the assessment of the left ventricle (LV) and functional right ventricle (fRV), including ejection fraction (EF), end-diastolic, end-systolic, and stroke volumes indexed by body surface area (respectively: EDVind, ESVind, SVind), and presence of hypertrabeculation defined according to Jacquier (1) as trabeculation mass >20% of the LV mass; b) cardiopulmonary tests with the assessment of peak oxygen consumption (peak VO2, % of predicted peak VO2), ventilation/carbon dioxide slope (VE/VCO2 slope) c) brain natriuretic peptide (BNP). Results Left ventricular hypertrabeculation was present in 13 (37.1%) patients. We demonstrated no difference between patients with and without LV hypertrabeculation regarding: s Conclusions Left ventricular hypertrabeculation demonstrated by cardiac magnetic resonance is a phenomenon frequently occurring among adults with Ebstein anomaly. However, its presence is not associated with both ventricles' worse function nor with reduced exercise capacity. Therefore, the clinical relevance of left ventricular hypertrabeculation in this population remains questionable and requires further prospective studies. FUNDunding Acknowledgement Type of funding sources: None.

scholarly journals Comparison of the effects of carvedilol and nebivolol on diastolic functions of the left ventricle in patients with non-ischemic heart failure

2014 ◽  
Vol 21 (1) ◽  
pp. 76-82 ◽  
Author(s):  
Abdullah Dogan ◽  
Mustafa Karabacak ◽  
Şenol Tayyar ◽  
Dogan Erdogan ◽  
Mehmet Ozaydin
Keyword(s):  
Heart Failure ◽  
Left Ventricle ◽  
Ischemic Heart ◽  
Ischemic Heart Failure ◽  
Diastolic Functions

1H nuclear magnetic resonance based metabolic urinary profiling of patients with ischemic heart failure

2011 ◽  
Vol 44 (4) ◽  
pp. 293-299 ◽  
Author(s):  
Seok-Min Kang ◽  
Jong-Chul Park ◽  
Min-Jeong Shin ◽  
Hyeran Lee ◽  
Jaewon Oh ◽  
...  
Keyword(s):  
Heart Failure ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Ischemic Heart ◽  
Ischemic Heart Failure ◽  
1H Nuclear Magnetic Resonance ◽  
Nuclear Magnetic

scholarly journals Cardiac Magnetic Resonance: A Multi-Parametric Imaging to Guide Management in Chronic Ischemic Heart Failure

2017 ◽  
pp. 49-58
Author(s):  
Novi Anggriyani
Keyword(s):  
Heart Failure ◽  
Cardiac Magnetic Resonance ◽  
Magnetic Resonance ◽  
Imaging Modality ◽  
Public Health Problem ◽  
Left Ventricular ◽  
Ischemic Heart ◽  
Parametric Imaging ◽  
Major Public Health Problem ◽  
High Prevalence

Chronic heart failure is a major public-health problem with a high prevalence, high mortality and complex treatment. A comprehensive analysis is needed to provide optimal therapy to these patients. Non-invasive imaging plays a central part by offering a complete approach in patients with ischemic heart disease (IHD). Cardiac magnetic resonance imaging (CMR) has emerged as an established advanced multi-parametric imaging modality for the functional and anatomical assessment of cardiovascular disease. This review describes the practical aspects of CMR imaging, and then discusses the role of CMR in the diagnosis and management of chronic IHD, its infarct related complications, such as secondary mitral regurgitation, left ventricular (LV) thrombus, and ventricular tachycardia (VT).

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