Predictive Role of Intraoperative Serum Brain Natriuretic Peptide for Early Allograft Dysfunction in Living Donor Liver Transplantation

2016 ◽  
Vol 21 ◽  
pp. 538-549 ◽  
Author(s):  
Min Suk Chae ◽  
Jung Min Koo ◽  
Chul Soo Park
Keyword(s):  
Liver Transplantation ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
Predictive Role ◽  
Early Allograft Dysfunction

scholarly journals Uric Acid as a Predictor for Early Allograft Dysfunction after Living Donor Liver Transplantation: A Prospective Observational Study

2021 ◽  
Vol 10 (12) ◽  
pp. 2729
Author(s):  
Li-Min Hu ◽  
Hsin-I Tsai ◽  
Chao-Wei Lee ◽  
Hui-Ming Chen ◽  
Wei-Chen Lee ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Uric Acid ◽  
Observational Study ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Prospective Observational Study ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
Allograft Dysfunction ◽  
Early Allograft Dysfunction

Early allograft dysfunction (EAD) is a postoperative complication that may cause graft failure and mortality after liver transplantation. The objective of this study was to examine whether the preoperative serum uric acid (SUA) level may predict EAD. We performed a prospective observational study, including 61 donor/recipient pairs who underwent living donor liver transplantation (LDLT). In the univariate and multivariate analysis, SUA ≤4.4 mg/dL was related to a five-fold (odds ratio (OR): 5.16, 95% confidence interval (CI): 1.41–18.83; OR: 5.39, 95% CI: 1.29–22.49, respectively) increased risk for EAD. A lower preoperative SUA was related to a higher incidence of and risk for EAD. Our study provides a new predictor for evaluating EAD and may exert a protective effect against EAD development.

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