Post-Transplant Lymphoproliferative Disorder (PTLD) Manifesting in the Oral Cavity of a 13-Year-Old Liver Transplant Recipient (LTx)

2015 ◽  
Vol 20 ◽  
pp. 478-482 ◽  
Author(s):  
Dorota Olczak-Kowalczyk
Keyword(s):  
Transplant Recipient ◽  
Oral Cavity ◽  
Liver Transplant ◽  
Lymphoproliferative Disorder ◽  
Liver Transplant Recipient ◽  
Post Transplant

scholarly journals First confirmed case of native Polyomavirus BK nephropathy in a liver transplant recipient seven years post-transplant

2015 ◽  
Vol 14 (1) ◽  
pp. 137-140 ◽  
Author(s):  
Yangmin Zeng ◽  
Alex Magil ◽  
Trana Hussaini ◽  
C. Kit Yeung ◽  
Siegfried R. Erb ◽  
...  
Keyword(s):  
Transplant Recipient ◽  
Liver Transplant ◽  
Liver Transplant Recipient ◽  
Post Transplant ◽  
Polyomavirus Bk

scholarly journals Complete regression of generalized plasmacytoma of lymph nodes in a liver transplant recipient during the conversion of immunosuppressive therapy from tacrolimus to everolimus

2021 ◽  
Vol 13 (3) ◽  
pp. 272-279
Author(s):  
V. E. Syutkin ◽  
V. R. Gorodetskiy ◽  
A. A. Salienko ◽  
N. A. Probatova ◽  
N. A. Kupryshina ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Transplant Recipient ◽  
Lymph Nodes ◽  
Liver Transplant ◽  
Immunosuppressive Therapy ◽  
Liver Transplant Recipient ◽  
Calcineurin Inhibitors ◽  
Lymphoproliferative Diseases ◽  
Post Transplant

Introduction. One of the serious complications after transplantation of solid organs and bone marrow is the development of post-transplant lymphoproliferative diseases.Clinical case. To evaluate the course of post-transplant lymphoproliferative diseases in the long-term in a liver transplant recipient after conversion of immunosuppressive therapy from tacrolimus to everolimus. We analyze a case of generalized primary plasmacytoma of lymph nodes with bone marrow involvement in a patient after liver transplantation.Results. After conversion of immunosuppression we observed a rapid positive trend: decreasing size of lymph nodes and regression of the level of paraprotein down to its complete disappearance. There were neither adverse events associated with everolimus for four years, nor signs of immunosuppression insufficiency.Conclusion. This Case Report is the first description of a long-term remission of nodal plasmacytoma that developed in a liver transplant recipient after complete withdrawal of calcineurin inhibitors and administration of everolimus. We suggest that the regression of post-transplant lymphoproliferative diseases after replacing calcineurin inhibitors with everolimus is associated not only with the minimization of calcineurin inhibitors exposure, but also with the antitumor effect of the everolimus itself, which prompts us to discuss the possibilities of expanding its clinical application.

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