scholarly journals The Effect of Human Chorionic Gonadotropin on the Development and Function of Bovine Corpus Luteum.

2001 ◽  
Vol 47 (5) ◽  
pp. 283-294 ◽  
Author(s):  
Masahiko NISHIGAI ◽  
Akiko TAKAMURA ◽  
Hideo KAMOMAE ◽  
Tomomi TANAKA ◽  
Yoshihiro KANEDA
Keyword(s):  
Corpus Luteum ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Bovine Corpus Luteum ◽  
And Function

scholarly journals Equine Chorionic Gonadotropin Modulates the Expression of Genes Related to the Structure and Function of the Bovine Corpus Luteum

PLoS ONE ◽  
2016 ◽  
Vol 11 (10) ◽  
pp. e0164089 ◽  
Author(s):  
Liza Margareth Medeiros de Carvalho Sousa ◽  
Gabriela Pacheco Mendes ◽  
Danila Barreiro Campos ◽  
Pietro Sampaio Baruselli ◽  
Paula de Carvalho Papa
Keyword(s):  
Corpus Luteum ◽  
Chorionic Gonadotropin ◽  
Structure And Function ◽  
Expression Of Genes ◽  
Bovine Corpus Luteum ◽  
Equine Chorionic Gonadotropin ◽  
And Function

Function of the human corpus luteum during the puerperium: Its maintenance by exogenous human chorionic gonadotropin

1971 ◽  
Vol 110 (5) ◽  
pp. 612-618 ◽  
Author(s):  
William J. LeMaire ◽  
Patricia W. Conly ◽  
Alfred Moffett ◽  
William N. Spellacy ◽  
William W. Cleveland ◽  
...  
Keyword(s):  
Corpus Luteum ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Human Corpus Luteum

scholarly journals Possible role of interferon tau on the bovine corpus luteum and neutrophils during the early pregnancy

Reproduction ◽  
2015 ◽  
Vol 150 (3) ◽  
pp. 217-225 ◽  
Author(s):  
Koumei Shirasuna ◽  
Haruka Matsumoto ◽  
Shuichi Matsuyama ◽  
Koji Kimura ◽  
Heinrich Bollwein ◽  
...  
Keyword(s):  
Corpus Luteum ◽  
Neutrophil Migration ◽  
Peripheral Circulation ◽  
Interferon Tau ◽  
Bovine Corpus Luteum ◽  
Activated Neutrophils ◽  
Endocrine Factor ◽  
Uterine Environment ◽  
And Function

When pregnancy is established, interferon tau (IFNT), a well-known pregnancy recognition signal in ruminants, is secreted by embryonic trophoblast cells and acts within the uterus to prepare for pregnancy. IFNT acts as an endocrine factor on the corpus luteum (CL) to induce refractory ability against the luteolytic action of PGF2α. Hypothesising that IFNT may influence not only the uterine environment but also the CL in cows via local or peripheral circulation, we investigated qualitative changes in the CL of pregnant cows during the maternal recognition period (day 16) and the CL of non-pregnant cows. The CL of pregnant animals had a higher number of neutrophils, and the expression of interleukin 8 (IL8) mRNA and its protein was higher as well as compared with the CL of non-pregnant animals. Although IFNT did not affect progesterone (P4) secretion and neutrophil migration directly, it stimulated IL8 mRNA expression on luteal cells (LCs), influencing the neutrophils, resulting in the increased migration of IFNT-activated neutrophils. Moreover, both IFNT-activated neutrophils and IL8 increased P4 secretion from LCs in vitro. Our novel finding was the increase in neutrophils and IL8 within the CL of pregnant cows, suggesting the involvement of IFNT function within the CL toward establishment of pregnancy in cows. The present results suggest that IFNT upregulates neutrophil numbers and function via IL8 on LCs in the CL of early pregnant cows and that both neutrophils and IL8, stimulated by IFNT, are associated with an increase in P4 concentrations during the maternal recognition period in cows.

scholarly journals Expression and Localization of Secreted Frizzled-Related Protein-4 in the Rodent Ovary: Evidence for Selective Up-Regulation in Luteinized Granulosa Cells

Endocrinology ◽  
2003 ◽  
Vol 144 (10) ◽  
pp. 4597-4606 ◽  
Author(s):  
Minnie Hsieh ◽  
Sabine M. Mulders ◽  
Robert R. Friis ◽  
Arun Dharmarajan ◽  
JoAnne S. Richards
Keyword(s):  
Chorionic Gonadotropin ◽  
Granulosa Cells ◽  
Human Chorionic Gonadotropin ◽  
Follicular Development ◽  
Corpora Lutea ◽  
Related Protein ◽  
Rich Domain ◽  
And Function ◽  
Periovulatory Follicles

Secreted frizzled-related protein-4 (sFRP-4) belongs to a family of soluble proteins that have a Frizzled-like cysteine-rich domain and function as modulators of Wnt-Frizzled (Fz) signals. As several Wnts and Fz are expressed at defined stages of follicular development in rodent ovaries, these studies were undertaken to evaluate the hormone-regulated expression and localization of sFRP-4. In the mouse ovary, the expression of sFRP-4 mRNA was up-regulated in granulosa cells of large antral follicles after human chorionic gonadotropin administration and was also elevated in corpora lutea, as determined by RT-PCR and in situ hybridization analyses. In hypophysectomized rat ovaries, sFRP-4 expression was similarly induced by human chorionic gonadotropin and further up-regulated by PRL. PRL also stimulated the secretion of sFRP-4 protein from luteinized rat granulosa cells in culture. Therefore, regulation of sFRP-4 by LH and PRL may be important for modulating Fz-1, which is known to be expressed in periovulatory follicles, and Wnt-4/Fz-4, which are expressed in corpora lutea.

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