scholarly journals Possible Involvement of Insulin-like Growth Factor-I in Mediating the Stimulatory Effect of Recombinant Bovine Growth Hormone on Maturation of Bovine Oocytes In Vitro.

1998 ◽  
Vol 44 (3) ◽  
pp. 243-251 ◽  
Author(s):  
Kosuke IGA ◽  
Koji NIWA ◽  
Andrzej BARTKE
2002 ◽  
Vol 57 (7) ◽  
pp. 1793-1800 ◽  
Author(s):  
Zahra J Champion ◽  
Mark H Vickers ◽  
Curtis G Gravance ◽  
Bernard H Breier ◽  
Patrick J Casey

1989 ◽  
Vol 56 (1) ◽  
pp. 17-26 ◽  
Author(s):  
Colin G. Prosser ◽  
Ivan R. Fleet ◽  
Anthony N. Corps

SummarySix lactating, non-pregnant Jersey cows were given subcutaneous injections of recombinantly derived bovine growth hormone for 7 d. Milk yield was increased by 4·5 kg/d on d 7, compared with the average yield of 10·7 ± 0·4 kg/d (mean ± s. e. m.) for the 7d preceding treatment. Concentrations of insulin-like growth factor I (IGF-I) in the milk increased from 0·44 ± 0·04 nmol/1 (mean ± s. e. m.) during the 7 d preceding treatment to 1·6 ± 0·2 nmol/1 on d 7 of treatment. Taking the increase in milk yield into account the total increase in the secretion of IGF-I into milk of one udder half was 6-fold. Plasma concentrations of total IGF-I rose from 15·5 + 1·3 nmol/1 (mean ± s. e. m.) on the day preceding treatment to 56·9 ± 3·6 nmol/1 (mean ± s. e. m.) on d 7 of treatment. Mammary plasma flow increased from 1·6 ± 0·09 to 2·2 ± 0·06 1/min udder half over the same time. Estimates of the amount of IGF-I that reached the mammary gland gave values of 24 and 116 nmol/min udder half before and during treatment respectively. IGF-I in milk of treated cows was associated predominantly with proteins ranging from 40000 to 150000 mol. wt, but a significant proportion (19%) of the total IGF-I was present in the free unbound form. IGF-I crosslinking studies revealed the presence in milk of one specifically labelled band at 31000 mol. wt.


1991 ◽  
Vol 62 (10) ◽  
pp. 933-938 ◽  
Author(s):  
Akihito OZAWA ◽  
Kouichi HODATE ◽  
Susumu MIYAMOTO ◽  
Fumihiro OHTANI ◽  
Toshio TSUSHIMA ◽  
...  

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