scholarly journals Immunohistochemical characterization of the arcuate kisspeptin/neurokinin B/dynorphin (KNDy) and preoptic kisspeptin neuronal populations in the hypothalamus during the estrous cycle in heifers

2016 ◽  
Vol 62 (5) ◽  
pp. 471-477 ◽  
Author(s):  
A HASSANEEN ◽  
Yousuke NANIWA ◽  
Yuta SUETOMI ◽  
Shuichi MATSUYAMA ◽  
Koji KIMURA ◽  
...  
Keyword(s):  
Estrous Cycle ◽  
Neurokinin B ◽  
Neuronal Populations

scholarly journals Characterization of a neurokinin B receptor site in rat brain using a highly selective radioligand.

1986 ◽  
Vol 261 (22) ◽  
pp. 10257-10263
Author(s):  
R Laufer ◽  
C Gilon ◽  
M Chorev ◽  
Z Selinger
Keyword(s):  
Rat Brain ◽  
Receptor Site ◽  
Neurokinin B

scholarly journals Characterization of biological types of cattle (Cycle VII): Influence of postpartum interval and estrous cycle length on fertility12

2007 ◽  
Vol 85 (9) ◽  
pp. 2156-2162 ◽  
Author(s):  
R. A. Cushman ◽  
M. F. Allan ◽  
R. M. Thallman ◽  
L. V. Cundiff
Keyword(s):  
Estrous Cycle ◽  
Cycle Length

scholarly journals KNDy Neurons Modulate the Magnitude of the Steroid-Induced Luteinizing Hormone Surges in Ovariectomized Rats

Endocrinology ◽  
2015 ◽  
Vol 156 (11) ◽  
pp. 4200-4213 ◽  
Author(s):  
Cleyde V. Helena ◽  
Natalia Toporikova ◽  
Bruna Kalil ◽  
Andrea M. Stathopoulos ◽  
Veronika V. Pogrebna ◽  
...  
Keyword(s):  
Negative Feedback ◽  
Arcuate Nucleus ◽  
Ovariectomized Rats ◽  
Neurokinin B ◽  
Lh Surge ◽  
Neuronal Populations ◽  
Lh Release ◽  
Positive And Negative Feedback ◽  
Kndy Neurons ◽  
Lh Secretion

Kisspeptin is the most potent stimulator of LH release. There are two kisspeptin neuronal populations in the rodent brain: in the anteroventral periventricular nucleus (AVPV) and in the arcuate nucleus. The arcuate neurons coexpress kisspeptin, neurokinin B, and dynorphin and are called KNDy neurons. Because estradiol increases kisspeptin expression in the AVPV whereas it inhibits KNDy neurons, AVPV and KNDy neurons have been postulated to mediate the positive and negative feedback effects of estradiol on LH secretion, respectively. Yet the role of KNDy neurons during the positive feedback is not clear. In this study, ovariectomized rats were microinjected bilaterally into the arcuate nucleus with a saporin-conjugated neurokinin B receptor agonist for targeted ablation of approximately 70% of KNDy neurons. In oil-treated animals, ablation of KNDy neurons impaired the rise in LH after ovariectomy and kisspeptin content in both populations. In estradiol-treated animals, KNDy ablation did not influence the negative feedback of steroids during the morning. Surprisingly, KNDy ablation increased the steroid-induced LH surges, accompanied by an increase of kisspeptin content in the AVPV. This increase seems to be due to lack of dynorphin input from KNDy neurons to the AVPV as the following: 1) microinjections of a dynorphin antagonist into the AVPV significantly increased the LH surge in estradiol-treated rats, similar to KNDy ablation, and 2) intra-AVPV microinjections of dynorphin in KNDy-ablated rats restored LH surge levels. Our results suggest that KNDy neurons provide inhibition to AVPV kisspeptin neurons through dynorphin and thus regulate the amplitude of the steroid-induced LH surges.

scholarly journals Isolation and Characterization of a 30-kDa Endometrial Glycoprotein Synthesized during the Estrous Cycle and Early Pregnancy of the Pig1

1995 ◽  
Vol 53 (5) ◽  
pp. 1038-1050 ◽  
Author(s):  
Rodney D. Geisert ◽  
Mendan J. Dixon ◽  
Thea Pratt ◽  
Raymond A.M. Schmitt ◽  
Bruce A. Lessley ◽  
...  
Keyword(s):  
Estrous Cycle ◽  
Early Pregnancy ◽  
Isolation And Characterization

scholarly journals Fast Readout of Object Identity from Macaque Inferior Temporal Cortex

Science ◽  
2005 ◽  
Vol 310 (5749) ◽  
pp. 863-866 ◽  
Author(s):  
Chou P. Hung ◽  
Gabriel Kreiman ◽  
Tomaso Poggio ◽  
James J. DiCarlo
Keyword(s):  
Neural Coding ◽  
Temporal Cortex ◽  
Population Level ◽  
Inferior Temporal Cortex ◽  
Object Identity ◽  
Neuronal Populations ◽  
Novel Objects ◽  
Coarse Information ◽  
Short Time

Understanding the brain computations leading to object recognition requires quantitative characterization of the information represented in inferior temporal (IT) cortex. We used a biologically plausible, classifier-based readout technique to investigate the neural coding of selectivity and invariance at the IT population level. The activity of small neuronal populations (∼100 randomly selected cells) over very short time intervals (as small as 12.5 milliseconds) contained unexpectedly accurate and robust information about both object “identity” and “category.” This information generalized over a range of object positions and scales, even for novel objects. Coarse information about position and scale could also be read out from the same population.

Characterization of the binding of [125I-iodo-histidyl,methyl-Phe7] neurokinin B to the neurokinin-3 receptor

Neuropeptides ◽  
1993 ◽  
Vol 24 (6) ◽  
pp. 317-319 ◽  
Author(s):  
S. Sadowski ◽  
R.-R.C. Huang ◽  
T.M. Fong ◽  
O. Marko ◽  
M.A. Cascieri
Keyword(s):  
Neurokinin B ◽  
Neurokinin 3 Receptor
Sign in / Sign up

Export Citation Format

Share Document