scholarly journals Acute Changes in Circulating Concentrations of Progesterone and Nitric Oxide and Partial Pressure of Oxygen During Prostaglandin F2α-induced Luteolysis in Cattle

2009 ◽  
Vol 55 (2) ◽  
pp. 149-155 ◽  
Author(s):  
Tomas Javier ACOSTA ◽  
Mamadou Bousa BAH ◽  
Anna KORZEKWA ◽  
Izabela WOCLAWEK-POTOCKA ◽  
Wlodzimierz MARKIEWICZ ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Partial Pressure ◽  
Prostaglandin F2α ◽  
Partial Pressure Of Oxygen ◽  
Acute Changes

Effects of pulsed inhaled nitric oxide delivery on the distribution of pulmonary perfusion in spontaneously breathing and mechanically ventilated anesthetized ponies

2022 ◽  
pp. 1-9
Author(s):  
Adam Auckburally ◽  
Maja K. Wiklund ◽  
Peter F. Lord ◽  
Göran Hedenstierna ◽  
Görel Nyman
Keyword(s):  
Nitric Oxide ◽  
Partial Pressure ◽  
Inhaled Nitric Oxide ◽  
Right Atrial ◽  
Facial Artery ◽  
Mixed Venous Blood ◽  
Pulmonary Perfusion ◽  
Partial Pressure Of Oxygen ◽  
Mechanically Ventilated ◽  
Spontaneously Breathing

Abstract OBJECTIVE To measure changes in pulmonary perfusion during pulsed inhaled nitric oxide (PiNO) delivery in anesthetized, spontaneously breathing and mechanically ventilated ponies positioned in dorsal recumbency. ANIMALS 6 adult ponies. PROCEDURES Ponies were anesthetized, positioned in dorsal recumbency in a CT gantry, and allowed to breathe spontaneously. Pulmonary artery, right atrial, and facial artery catheters were placed. Analysis time points were baseline, after 30 minutes of PiNO, and 30 minutes after discontinuation of PiNO. At each time point, iodinated contrast medium was injected, and CT angiography was used to measure pulmonary perfusion. Thermodilution was used to measure cardiac output, and arterial and mixed venous blood samples were collected simultaneously and analyzed. Analyses were repeated while ponies were mechanically ventilated. RESULTS During PiNO delivery, perfusion to aerated lung regions increased, perfusion to atelectatic lung regions decreased, arterial partial pressure of oxygen increased, and venous admixture and the alveolar-arterial difference in partial pressure of oxygen decreased. Changes in regional perfusion during PiNO delivery were more pronounced when ponies were spontaneously breathing than when they were mechanically ventilated. CLINICAL RELEVANCE In anesthetized, dorsally recumbent ponies, PiNO delivery resulted in redistribution of pulmonary perfusion from dependent, atelectatic lung regions to nondependent aerated lung regions, leading to improvements in oxygenation. PiNO may offer a treatment option for impaired oxygenation induced by recumbency.

Effects of ambient pressure on pulmonary nitric oxide

2012 ◽  
Vol 112 (4) ◽  
pp. 580-586 ◽  
Author(s):  
Tryggve E. Hemmingsson ◽  
Dag Linnarsson ◽  
Claes Frostell ◽  
Alain Van Muylem ◽  
Yannick Kerckx ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Partial Pressure ◽  
Ambient Pressure ◽  
Normal Pressure ◽  
Alternative Interpretation ◽  
Low Density ◽  
Oxygen Breathing ◽  
No Formation ◽  
Exhaled No ◽  
Acute Changes

Airway nitric oxide (NO) has been proposed to play a role in the development of high-altitude pulmonary edema. We undertook a study of the effects of acute changes of ambient pressure on exhaled and alveolar NO in the range 0.5–4 atmospheres absolute (ATA, 379–3,040 mmHg) in eight healthy subjects breathing normoxic nitrogen-oxygen mixtures. On the basis of previous work with inhalation of low-density helium-oxygen gas, we expected facilitated backdiffusion and lowered exhaled NO at 0.5 ATA and the opposite at 4 ATA. Instead, the exhaled NO partial pressure (PeNO) did not differ between pressures and averaged 1.21 ± 0.16 (SE) mPa across pressures. As a consequence, exhaled NO fractions varied inversely with pressure. Alveolar estimates of the NO partial pressure differed between pressures and averaged 88 ( P = 0.04) and 176 ( P = 0.009) percent of control (1 ATA) at 0.5 and 4 ATA, respectively. The airway contribution to exhaled NO was reduced to 79% of control ( P = 0.009) at 4 ATA. Our finding of the same PeNO at 0.5 and 1 ATA is at variance with previous findings of a reduced PeNO with inhalation of low-density gas at normal pressure, and this discrepancy may be due to the much longer durations of low-density gas breathing in the present study compared with previous studies with helium-oxygen breathing. The present data are compatible with the notion of an enhanced convective backtransport of NO, compensating for attenuated backdiffusion of NO with increasing pressure. An alternative interpretation is a pressure-induced suppression of NO formation in the airways.

Interaction of H2O, O2 and H2 with Proton Conducting Oxides Based on Lanthanum Scandates

2019 ◽  
pp. 88-100
Author(s):  
A. S. Farlenkov ◽  
N. A. Zhuravlev ◽  
Т. A. Denisova ◽  
М. V. Ananyev
Keyword(s):  
Water Vapor ◽  
Partial Pressure ◽  
Gas Phase ◽  
Molecular Hydrogen ◽  
Proton Magnetic Resonance ◽  
Partial Pressure Of Oxygen ◽  
Proton Conducting ◽  
Conducting Oxides ◽  
Temperature Range ◽  
Apparent Level

The research uses the method of high-temperature thermogravimetric analysis to study the processes of interaction of the gas phase in the temperature range 300–950 °C in the partial pressure ranges of oxygen 8.1–50.7 kPa, water 6.1–24.3 kPa and hydrogen 4.1 kPa with La1–xSrxScO3–α oxides (x = 0; 0.04; 0.09). In the case of an increase in the partial pressure of water vapor at a constant partial pressure of oxygen (or hydrogen) in the gas phase, the apparent level of saturation of protons is shown to increase. An increase in the apparent level of saturation of protons of the sample also occurs with an increase in the partial pressure of oxygen at a constant partial pressure of water vapor in the gas phase. The paper discusses the causes of the observed processes. The research uses the hydrogen isotope exchange method with the equilibration of the isotope composition of the gas phase to study the incorporation of hydrogen into the structure of proton-conducting oxides based on strontium-doped lanthanum scandates. The concentrations of protons and deuterons were determined in the temperature range of 300–800 °C and a hydrogen pressure of 0.2 kPa for La0.91Sr0.09ScO3–α oxide. The paper discusses the role of oxygen vacancies in the process of incorporation of protons and deuterons from the atmosphere of molecular hydrogen into the structure of the proton conducting oxides La1–xSrxScO3–α (x = 0; 0.04; 0.09). The proton magnetic resonance method was used to study the local structure in the temperature range 23–110 °C at a rotation speed of 10 kHz (MAS) for La0.96Sr0.04ScO3–α oxide after thermogravimetric measurements in an atmosphere containing water vapor, and after exposures in molecular hydrogen atmosphere. The existence of proton defects incorporated into the volume of the investigated proton oxide from both the atmosphere containing water and the atmosphere containing molecular hydrogen is unambiguously shown. The paper considers the effect of the contributions of the volume and surface of La0.96Sr0.04ScO3–α oxide on the shape of the proton magnetic resonance spectra.

Biorhythm of the partial pressure of oxygen in uterine and fetal tissues

1981 ◽  
Vol 92 (4) ◽  
pp. 1305-1307
Author(s):  
A. Ya. Chizhov ◽  
V. G. Filimonov ◽  
Yu. M. Karash ◽  
R. B. Strelkov
Keyword(s):  
Partial Pressure ◽  
Partial Pressure Of Oxygen ◽  
Fetal Tissues

Effect of prostaglandin F2α (PGF2α) on oviductal nitric oxide synthase (NOS) activity: possible role of endogenous NO on PGF2α-induced contractions in rat oviduct

1998 ◽  
Vol 56 (2-3) ◽  
pp. 155-166 ◽  
Author(s):  
Silvina Perez Martinez ◽  
Ana Marı́a Franchi ◽  
Juan Marcelo Viggiano ◽  
Marı́a Belén Herrero ◽  
Martha Gimeno
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Prostaglandin F2α ◽  
Oxide Synthase

Singlet oxygen feedback delayed fluorescence of protoporphyrin IX in organic solutions

2017 ◽  
Vol 16 (4) ◽  
pp. 507-518 ◽  
Author(s):  
Ivo S. Vinklárek ◽  
Marek Scholz ◽  
Roman Dědic ◽  
Jan Hála
Keyword(s):  
Partial Pressure ◽  
Singlet Oxygen ◽  
Protoporphyrin Ix ◽  
Clinical Applications ◽  
Delayed Fluorescence ◽  
Diagnostic Tools ◽  
Partial Pressure Of Oxygen ◽  
High Concentrations ◽  
Organic Solutions

The PpIX DF show the significant role of SOFDF mechanism at high concentrations and at atmospheric partial pressure of oxygen and should be considered when developing diagnostic tools for clinical applications.

Oxygen Poisoning in a Hyperbaric Environment

1970 ◽  
Vol 56 (1) ◽  
pp. 39-47
Author(s):  
J. Murray Young
Keyword(s):  
Partial Pressure ◽  
Sea Water ◽  
Signs And Symptoms ◽  
Pressure Chamber ◽  
Partial Pressure Of Oxygen ◽  
Oxygen Exposure ◽  
Rapid Decompression ◽  
Hyperbaric Environment ◽  
Biochemical Mechanisms ◽  
Oxygen Poisoning

AbstractThe biochemical mechanisms of oxygen poisoning are discussed together with the signs and symptoms produced clinically. Investigation of 35 subjects performing work (mean 02 consumption 1.4 l./min) for 40 minutes in a pressure chamber at simulated depths of 20 to 47 feet of sea water showed that this degree of exercise markedly reduced the oxygen exposure tolerance of the subjects. This investigation also showed that rapid decompression of subjects breathing oxygen can produce an exacerbation of existing symptoms and these results are discussed.It is stressed that any breathing mixture containing a partial pressure of oxygen in excess of 150 torr constitutes an environment which is hyperbaric with respect to oxygen and caution is advised in the administration of oxygen to any patient.

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