scholarly journals Optimization of apolipoprotein B mRNA editing by APOBEC1 apoenzyme and the role of its auxiliary factor, ACF

RNA ◽  
2004 ◽  
Vol 10 (9) ◽  
pp. 1399-1411 ◽  
Author(s):  
A. CHESTER
Keyword(s):  
Apolipoprotein B ◽  
Mrna Editing ◽  
Auxiliary Factor

scholarly journals HPV Meets APOBEC: New Players in Head and Neck Cancer

2021 ◽  
Vol 22 (3) ◽  
pp. 1402
Author(s):  
Giuseppe Riva ◽  
Camilla Albano ◽  
Francesca Gugliesi ◽  
Selina Pasquero ◽  
Sergio Fernando Castillo Pacheco ◽  
...  
Keyword(s):  
Head And Neck ◽  
Apolipoprotein B ◽  
Hpv Infection ◽  
Innate Immune ◽  
Mrna Editing ◽  
Ongoing Research ◽  
Cytidine Deaminases ◽  
Editing Enzyme ◽  
Apobec Family

Besides smoking and alcohol, human papillomavirus (HPV) is a factor promoting head and neck squamous cell carcinoma (HNSCC). In some human tumors, including HNSCC, a number of mutations are caused by aberrantly activated DNA-modifying enzymes, such as the apolipoprotein B mRNA editing enzyme catalytic polypeptide-like (APOBEC) family of cytidine deaminases. As the enzymatic activity of APOBEC proteins contributes to the innate immune response to viruses, including HPV, the role of APOBEC proteins in HPV-driven head and neck carcinogenesis has recently gained increasing attention. Ongoing research efforts take the cue from two key observations: (1) APOBEC expression depends on HPV infection status in HNSCC; and (2) APOBEC activity plays a major role in HPV-positive HNSCC mutagenesis. This review focuses on recent advances on the role of APOBEC proteins in HPV-positive vs. HPV-negative HNSCC.

scholarly journals Mutational analysis of apolipoprotein B mRNA editing enzyme (APOBEC1): structure–function relationships of RNA editing and dimerization

1999 ◽  
Vol 40 (4) ◽  
pp. 623-635 ◽  
Author(s):  
Ba-Bie Teng ◽  
Scott Ochsner ◽  
Qian Zhang ◽  
Kizhake V. Soman ◽  
Paul P. Lau ◽  
...  
Keyword(s):  
Structure Function ◽  
Rna Editing ◽  
Apolipoprotein B ◽  
Mutational Analysis ◽  
Mrna Editing ◽  
Editing Enzyme

scholarly journals Apolipoprotein B mRNA editing. Direct determination of the edited base and occurrence in non-apolipoprotein B-producing cell lines.

1990 ◽  
Vol 265 (36) ◽  
pp. 22446-22452 ◽  
Author(s):  
K Boström ◽  
Z Garcia ◽  
K S Poksay ◽  
D F Johnson ◽  
A J Lusis ◽  
...  
Keyword(s):  
Cell Lines ◽  
Apolipoprotein B ◽  
Direct Determination ◽  
Mrna Editing

Apolipoprotein B mRNA Editing

2018 ◽  
pp. 297-317
Author(s):  
Nicholas O. Davidson
Keyword(s):  
Apolipoprotein B ◽  
Mrna Editing

scholarly journals The role of the LDL receptor in apolipoprotein B secretion

2000 ◽  
Vol 105 (4) ◽  
pp. 521-532 ◽  
Author(s):  
Jaap Twisk ◽  
Donald L. Gillian-Daniel ◽  
Angie Tebon ◽  
Lin Wang ◽  
P. Hugh R. Barrett ◽  
...  
Keyword(s):  
Apolipoprotein B ◽  
Ldl Receptor
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