Dual-source CT coronary angiography involving injection protocol with iodine load tailored to patient body weight and body mass index: Estimation of optimal contrast material dose

2013 ◽  
Vol 54 (2) ◽  
pp. 149-155 ◽  
Author(s):  
Xiaomei Zhu ◽  
Yinsu Zhu ◽  
Hai Xu ◽  
Guanyu Yang ◽  
Lijun Tang ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Weight ◽  
Coronary Angiography ◽  
Body Mass ◽  
Contrast Material ◽  
Ct Coronary Angiography ◽  
Dual Source Ct ◽  
Dual Source ◽  
Injection Protocol ◽  
Index Estimation

scholarly journals Coronary artery anomalies in adults: Imaging at dual source CT coronary angiography

2012 ◽  
Vol 57 (2) ◽  
pp. 184-190 ◽  
Author(s):  
Fotios Laspas ◽  
Arkadios Roussakis ◽  
Christos Mourmouris ◽  
Nikolaos Kritikos ◽  
Roxani Efthimiadou ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Angiography ◽  
Ct Coronary Angiography ◽  
Dual Source Ct ◽  
Coronary Artery Anomalies ◽  
Dual Source

Abstract 2598: Radiation Exposure, Procedure Time And Contrast Load In Patients Referred For Coronary Angiography: Head-to-head Comparison Of Dual Source Ct With Conventional Coronary Angiography.

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Carlos A Van Mieghem ◽  
Annick C Weustink ◽  
Marcel Kofflard ◽  
A. Schreve-Steensma ◽  
Niels A Matheijssen ◽  
...  
Keyword(s):  
Coronary Angiography ◽  
Radiation Exposure ◽  
Contrast Material ◽  
Conventional Coronary Angiography ◽  
Dual Source Ct ◽  
Procedure Time ◽  
X Ray ◽  
Iodinated Contrast ◽  
Dual Source ◽  
The Mean

Introduction and aim: Dual Source CT (DSCT) scanners, with an increased temporal resolution (83 ms), are becoming widely available. To evaluate the current potential of this scanner in the clinical arena, we performed a head-to-head comparison with conventional coronary angiography (CCA) taking into account the following parameters: radiation exposure, procedure time and contrast load. Methods: During a one-year period (april 2006 to march 2007) we compared a consecutive patient group who underwent DSCT (318 patients, 222 male, mean age 68±11 years) and CCA (352 patients, 258 male, mean age 61±12) respectively. Patients with previous bypass surgery were excluded. In DSCT, the volume of iodinated contrast material was adapted to the scan time. A contrast bolus was injected in an antecubital vein at a flow rate of 5.0 ml/s followed by a saline chaser of 40 ml at 5.0 ml/s. Each tube provided 412 mAs/rot (maximum), and full X-ray tube current was given during 25–70% of the RR-interval. Exposure data were collected using the x-ray dosimetrical reports from DSCT and CCA. Results: The mean procedure time using DSCT and CCA was 16.1±4.7 min and 44.1±25.5 min (p<0.001), respectively. The mean contrast load in DSCT and CCA was 77.9±7.6 ml and 175.3±4.3ml (p<0.001), respectively. The overall radiation exposure for DSCT and CCA was calculated as 15.3±4.0 mSv and 5.7±4.3 mSv, respectively. Radiation exposure with DSCT was significantly lower (p<0.001) in patients with a heart rate of >70 bpm (12.9±3.1 mSv ) as compared with patients with heart rates <70 bpm (16.4±3.8 mSv). Conclusion: In today’s practice currently available DSCT scanners perform favorably as compared with CCA, considering procedure time and patient contrast load. Radiation exposure with DSCT remains higher but should not be considered a major disadvantage taking into account the relatively old age group that generally undergoes coronary angiography and the major benefit of not being exposed to the risks of an invasive procedure.

Abstract 5804: Validation of a Body Mass Index Adapted Scanning Protocol for Low-Dose 64-Slice CT Coronary Angiography with Prospective ECG-Triggering

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Fuminari Tatsugami ◽  
Lars Husmann ◽  
Bernhard A Herzog ◽  
Nina Burkhard ◽  
Ines Valenta ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Coronary Angiography ◽  
Body Mass ◽  
Low Dose ◽  
Contrast Material ◽  
Image Noise ◽  
Effective Radiation Dose ◽  
Scanning Protocol ◽  
Effective Radiation ◽  
Prospective Ecg Triggering

As an increase in body mass index (BMI) confers a higher image noise in computed tomography coronary angiography (CTCA), we have validated a BMI-adapted scanning protocol for low-dose 64-slice CTCA with prospective electrocardiogram (ECG)-triggering. One-hundred-one consecutive patients underwent CTCA with prospective ECG-triggering, using a fixed contrast material protocol (80mL iodixanol, 50mL saline chaser, flow rate of 5mL/sec). Tube voltage and current were adapted to BMI (table ). Attenuation (Houndsfield units, HU) was measured and contrast-to-noise ratio (CNR) calculated for the proximal right coronary artery (RCA) and left main artery (LMA). Image noise was determined as the standard deviation of attenuation in the ascending aorta. Mean BMI was 25.7±4.3kg/m 2 (range 18.2–38.8kg/m 2 ) the mean effective radiation dose was 2.1±0.7mSv (range 1.0 –3.2mSv). There was no significant correlation between BMI and image noise (r= 0.11, P = 0.284), indicating optimal protocol adjustment. However, BMI was inversely correlated to vessel attenuation (RCA: r=−0.45, P <0.001; LMA: r=−0.47, P <0.001), and CNR (RCA: r=−0.39, P <0.001; LMA: r=−0.37, P <0.001). The proposed BMI-adapted scanning parameters results in similar image noise regardless of BMI. Increased bolus dilution due to larger blood volume may have contributed to a decrease in CNR and vessel attenuation in higher BMI as a fixed contrast material bolus was used. Table

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