scholarly journals Analytical characteristics of the Roche highly sensitive troponin T assay and its application to a cardio-healthy population

2010 ◽  
Vol 47 (6) ◽  
pp. 524-528 ◽  
Author(s):  
G. Koerbin ◽  
J. R. Tate ◽  
P. E. Hickman
Keyword(s):  
Troponin T ◽  
Healthy Population ◽  
Highly Sensitive ◽  
Highly Sensitive Troponin

Highly Sensitive Troponin T in Patients with Acute Ischemic Stroke

2012 ◽  
Vol 68 (5) ◽  
pp. 287-293 ◽  
Author(s):  
J.K. Jensen ◽  
T. Ueland ◽  
P. Aukrust ◽  
L. Antonsen ◽  
S.R. Kristensen ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Troponin T ◽  
Highly Sensitive ◽  
Highly Sensitive Troponin

Highly sensitive troponin T dynamics and prognosis in asymptomatic severe aortic stenosis

2020 ◽  
Vol 73 (12) ◽  
pp. 1065-1066
Author(s):  
Elena Ferrer-Sistach ◽  
Josep Lupón ◽  
Germán Cediel ◽  
Elena Revuelta-López ◽  
Antoni Bayés-Genís
Keyword(s):  
Aortic Stenosis ◽  
Troponin T ◽  
Severe Aortic Stenosis ◽  
Highly Sensitive ◽  
Highly Sensitive Troponin

Elevated highly-sensitive troponin T and pulse wave velocity in mild chronic kidney disease

2021 ◽  
Vol 345 ◽  
pp. 19-20
Author(s):  
A.B. Md Radzi ◽  
R.E.F. Raja Shariff ◽  
M.H. Hamidi ◽  
H. Sani ◽  
K.S. Ibrahim ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Pulse Wave ◽  
Troponin T ◽  
Highly Sensitive ◽  
Highly Sensitive Troponin

scholarly journals Fast assessment and management of chest pain patients without ST-elevation in the pre-hospital gateway (FamouS Triage): ruling out a myocardial infarction at home with the modified HEART score

2017 ◽  
Vol 7 (2) ◽  
pp. 102-110 ◽  
Author(s):  
Maycel Ishak ◽  
Danish Ali ◽  
Marion J Fokkert ◽  
Robbert J Slingerland ◽  
Rudolf T Tolsma ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Chest Pain ◽  
Troponin T ◽  
St Segment Elevation ◽  
Heart Score ◽  
St Segment ◽  
Highly Sensitive ◽  
Highly Sensitive Troponin ◽  
Pain Patients

Background: The first study of the FamouS Triage project investigates the feasibility of ruling out a myocardial infarction in pre-hospital chest pain patients without electrocardiographic ST-segment elevation by using the modified HEART score at the patient’s home, incorporating only a single highly sensitive troponin T measurement. Methods: A venous blood sample was drawn in the ambulance from 1127 consecutive chest pain patients for measurement of the pre-hospital highly sensitive troponin T levels, in order to establish a pre-hospital HEART score (i.e. the modified HEART score) and evaluate the possibility of triage at the patient’s home. The primary endpoint was the occurrence of a major adverse cardiac event (MACE) i.e. acute myocardial infarction, percutaneous coronary intervention, coronary artery bypass grafting or death within 30 days after initial presentation. Results: Two hundred and six patients (18%) developed a MACE during 30 days of follow-up. Thirty-six per cent of the patients ( n=403) had a low modified HEART score (0–3 points) and none of them developed a MACE during follow-up. Forty-four per cent of the patients ( n=494) had an intermediate modified HEART score (4–6 points) and 18% of them developed a MACE. Twenty per cent of the patients ( n=230) had a high modified HEART score (7–10 points) of which 52% developed a MACE during follow-up. Conclusion: It seems feasible to rule out a myocardial infarction at home in chest pain patients without ST-segment elevation by using the modified HEART score. TRIAL ID: NTR4205. Dutch Trial Register [ http://www.trialregister.nl ]: trial number 4205.

scholarly journals Highly Sensitive Troponin Assays and the Cardiology Community: A Love/Hate Relationship?

2011 ◽  
Vol 57 (6) ◽  
pp. 826-829 ◽  
Author(s):  
James A de Lemos ◽  
David A Morrow ◽  
Christopher R deFilippi
Keyword(s):  
Cardiac Troponin ◽  
Cardiovascular Health ◽  
Troponin I ◽  
Troponin T ◽  
Cardiac Injury ◽  
Improve Patient Care ◽  
Fourth Generation ◽  
Highly Sensitive ◽  
Highly Sensitive Troponin ◽  
Improve Patient

Abstract The development of highly sensitive assays for cardiac troponin T (hs-cTnT)4 and cardiac troponin I (hs-cTnI) represents the latest technological advance in a field that has witnessed continual progression toward more sensitive and more precise tools for detecting cardiac injury. The hs-cTnT assay, for example, can detect cTnT concentrations 10-fold lower than the current fourth-generation assay, with high precision at the myocardial infarction (MI) detection limit. Despite the potential for such evolution to improve patient care, clinicians, including practicing cardiologists, often find themselves poorly prepared for the introduction of more-sensitive assays, because they fail to consider the implications of increasing sensitivity on the interpretation of the test results. We believe that highly sensitive troponin assays offer new opportunities to improve cardiovascular health, but they also present challenges in the areas in which troponin testing is most commonly used today.

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