Promoting High-Impact Entrepreneurship: An Evaluation of a Mexican Government Matching Grant Scheme

2016 ◽  
Author(s):  
David Atkin ◽  
Eric Verhoogen
Keyword(s):  
High Impact ◽  
Mexican Government ◽  
Matching Grant ◽  
Grant Scheme

Postmortem and in situ TEM methods to study the mechanism of failure in controlled-morphology high-impact polystrene resin

1996 ◽  
Vol 54 ◽  
pp. 178-179
Author(s):  
R. C. Cieslinski ◽  
M. T. Dineen ◽  
J. L. Hahnfeld
Keyword(s):  
Poisson Ratio ◽  
Acrylonitrile Butadiene Styrene ◽  
High Impact ◽  
In Situ Tem ◽  
Styrene Copolymers ◽  
Controlled Morphology ◽  
Point Bend ◽  
Mechanism Of Failure ◽  
Impact Energies

Advanced Styrenic resins are being developed throughout the industry to bridge the properties gap between traditional HIPS (High Impact Polystyrene) and ABS (Acrylonitrile-Butadiene-Styrene copolymers) resins. These new resins have an unprecedented balance of high gloss and high impact energies. Dow Chemical's contribution to this area is based on a unique combination of rubber morphologies including labyrinth, onion skin, and core-shell rubber particles. This new resin, referred as a controlled morphology resin (CMR), was investigated to determine the toughening mechanism of this unique rubber morphology. This poster will summarize the initial studies of these resins using the double-notch four-point bend test of Su and Yee, tensile stage electron microscopy, and Poisson Ratio analysis of the fracture mechanism.

The Collaborative Network Approach: a model for advancing patient-centric research for Castleman disease and other rare diseases

2019 ◽  
Vol 3 (1) ◽  
pp. 97-105
Author(s):  
Mary Zuccato ◽  
Dustin Shilling ◽  
David C. Fajgenbaum
Keyword(s):  
Rare Diseases ◽  
Treatment Options ◽  
Castleman Disease ◽  
High Impact ◽  
Collaborative Network ◽  
Network Approach ◽  
Grant Applications ◽  
Research Questions ◽  
Novel Strategy ◽  
Patient Centric

Abstract There are ∼7000 rare diseases affecting 30 000 000 individuals in the U.S.A. 95% of these rare diseases do not have a single Food and Drug Administration-approved therapy. Relatively, limited progress has been made to develop new or repurpose existing therapies for these disorders, in part because traditional funding models are not as effective when applied to rare diseases. Due to the suboptimal research infrastructure and treatment options for Castleman disease, the Castleman Disease Collaborative Network (CDCN), founded in 2012, spearheaded a novel strategy for advancing biomedical research, the ‘Collaborative Network Approach’. At its heart, the Collaborative Network Approach leverages and integrates the entire community of stakeholders — patients, physicians and researchers — to identify and prioritize high-impact research questions. It then recruits the most qualified researchers to conduct these studies. In parallel, patients are empowered to fight back by supporting research through fundraising and providing their biospecimens and clinical data. This approach democratizes research, allowing the entire community to identify the most clinically relevant and pressing questions; any idea can be translated into a study rather than limiting research to the ideas proposed by researchers in grant applications. Preliminary results from the CDCN and other organizations that have followed its Collaborative Network Approach suggest that this model is generalizable across rare diseases.

Pelvic Impairments

2018 ◽  
Vol 23 (4) ◽  
pp. 9-10
Author(s):  
James Talmage ◽  
Jay Blaisdell
Keyword(s):  
Pelvic Ring ◽  
Reproductive Organs ◽  
High Impact ◽  
Pelvic Fractures ◽  
Motor Dysfunction ◽  
Impact Event ◽  
Concomitant Injuries ◽  
Rating Process ◽  
Pass Through ◽  
A Minor

Abstract Pelvic fractures are relatively uncommon, and in workers’ compensation most pelvic fractures are the result of an acute, high-impact event such as a fall from a roof or an automobile collision. A person with osteoporosis may sustain a pelvic fracture from a lower-impact injury such as a minor fall. Further, major parts of the bladder, bowel, reproductive organs, nerves, and blood vessels pass through the pelvic ring, and traumatic pelvic fractures that result from a high-impact event often coincide with damaged organs, significant bleeding, and sensory and motor dysfunction. Following are the steps in the rating process: 1) assign the diagnosis and impairment class for the pelvis; 2) assign the functional history, physical examination, and clinical studies grade modifiers; and 3) apply the net adjustment formula. Because pelvic fractures are so uncommon, raters may be less familiar with the rating process for these types of injuries. The diagnosis-based methodology for rating pelvic fractures is consistent with the process used to rate other musculoskeletal impairments. Evaluators must base the rating on reliable data when the patient is at maximum medical impairment and must assess possible impairment from concomitant injuries.

Repräsentanz von Pflegewissenschaftlerinnen und Pflegewissenschaftlern aus dem deutschsprachigen Raum in Zeitschriften mit hohem Impact Factor

Pflege ◽  
2018 ◽  
Vol 31 (1) ◽  
pp. 31-39 ◽  
Author(s):  
Julian Hirt ◽  
Christian Buhtz ◽  
Benedikt Mersdorf ◽  
Gabriele Meyer
Keyword(s):  
Impact Factor ◽  
High Impact ◽  
Journal Citation Reports ◽  
Journal Citation

Zusammenfassung.Hintergrund: Die Häufigkeit pflegewissenschaftlicher Beiträge aus dem deutschsprachigen Raum in Zeitschriften mit hohem Impact Factor gibt Hinweise auf die Teilhabe der Disziplin am internationalen Diskurs. Bisherige Analysen beschränken sich auf pflegewissenschaftliche Zeitschriften. Diese konstatieren eine Unterrepräsentanz experimenteller Studien und klinischer Themen. Ziel: Identifikation und Analyse der Publikationen von im deutschsprachigen Raum ansässigen Pflegewissenschaftlerinnen/Pflegewissenschaftlern in internationalen pflegerelevanten High Impact Journals. Methode: Mittels Journal Citation Reports wurden pflegerelevante Zeitschriftenkategorien identifiziert, in denen die nach dem 5-Jahres-Impact-Factor höchsten 10 % der Zeitschriften der Jahre 2010 bis 2014 ausgewählt wurden. Der Einschluss der Publikationen und die Datenextraktion erfolgten durch zwei unabhängige Personen. Ergebnisse: Durchsucht wurden 106939 Publikationen aus 126 Zeitschriften. Eingeschlossen wurden 100 Publikationen, an denen 114 Pflegewissenschaftler/-innen aus dem deutschsprachigen Raum insgesamt 229 Mal beteiligt sind. Insgesamt 42 % sind Beobachtungsstudien, 11 % sind experimentelle Studien. Die berichteten Themen sind mehrheitlich klinisch orientiert (55 %). Über 50 % sind in den letzten zwei Jahren publiziert worden. Schlussfolgerungen: Das pflegewissenschaftliche Publikationsaufkommen aus dem deutschsprachigen Raum in High Impact Journals ist gering. Eine Zunahme über den Beobachtungszeitraum ist zu verzeichnen. Im Gegensatz zu früheren Analysen zeigt sich ein höherer Anteil klinischer Forschung.

A Cause for Chronic Maximizing: High Impact Expectations

2010 ◽  
Author(s):  
Jonas Kiesekoms ◽  
Maarten Elen ◽  
Mario Pandelaere ◽  
Maggie Geuens
Keyword(s):  
High Impact

Frakturreduktion durch körperliches Training – Welches Training für wen? Eine evidenzbasierte Übersicht über Trainingsstrategien bei Osteoporose

2020 ◽  
Vol 29 (03) ◽  
pp. 207-214
Author(s):  
Simon von Stengel ◽  
Wolfgang Kemmler
Keyword(s):  
High Impact ◽  
Körperliches Training ◽  
Osteoporotische Frakturen

ZusammenfassungOsteoporotische Frakturen sind ein hochrelevantes Problem unserer überalterten Gesellschaft. Die zentralen Zielparameter, welche in diesem Zusammenhang im Rahmen eines körperlichen Trainings angesteuert werden können, sind die Bereiche „Sturzhäufigkeit“ und „Knochenfestigkeit“ als wesentliche Determinanten des Frakturrisikos. Die Konzeption und Durchführung eines frakturwirksamen Trainings ist aus trainingswissenschaftlicher Sicht allerdings äußerst komplex und verlangt eine auf die anvisierte Zielsetzung und Personengruppe abgestimmte Komposition von Trainingsinhalten und Belastungsnormativen. Zur Senkung des Sturzrisikos sind neben einem gezielten Gleichgewichtstraining insbesondere multimodale Bewegungsprogramme, welche Gleichgewichts- und Kraftübungen beinhalten, geeignet. Für ein knochenwirksames Training können intensive osteogene Reize am Knochen über Muskelzüge im Rahmen eines Krafttrainings oder durch axiale Belastungen im Rahmen von gewichtstragenden High-impact-Übungen generiert werden. Ziel dieses Übersichtsartikels ist es, basierend auf der aktuellen Evidenz, Grundlagen und Strategien zur effektiven Frakturprophylaxe durch Sturzreduktion und positive Beeinflussung der Knochendichte durch körperliches Training herauszuarbeiten.

“Stay with me. Talk to me”: reader interaction strategies in modern poetry

2020 ◽  
Vol 7 (2) ◽  
pp. 419-436
Author(s):  
Olga Igorevna Severskaya
Keyword(s):  
Discourse Analysis ◽  
High Impact ◽  
Modern Poetry ◽  
Self Presentation ◽  
Communication Plan ◽  
Communicative Strategies ◽  
The World ◽  
Poetic Text ◽  
Communicative Context

The article is devoted to the consideration of a poetic text as a communicative phenomenon with a high impact potential. The author defines the features of poetic communication, which is both mass and interpersonal, and its main goal, which is the poet’s desire to communicate author’s vision of the world and thereby change the picture of the reader’s world, achieving empathy from it. Based on the understanding of the speech strategy as a cognitive communication plan, a program for generating and perceiving speech, the author talks about the fundamental reversibility of text-generating and interpretative strategies and offers own classification of strategies and tactics that are most often used in modern poetry. In this classification, the main communicative strategies of self-presentation and rapprochement with the reader are associated with auxiliary discursive strategies of actualizing, dramatizing and dialogizing the text and programming interpretations by tactics for highlighting objects and situations using sound “gestures”, pointing to the referent, framing, directly introducing the reader into the communicative context, attracting the recipient’s attention through appeals and pragmatic instructions, interrogation, and some others. Particular attention is paid to the multimodality of interactions and its specific manifestations in poetic discourse. The study is based on the material of Russian poetry of the 1980- 2000s using the methods of intent and discourse analysis.

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