Metal Chelating Agents III: Mass Spectral Studies on the Semicarbazone Derivatives of Benzoin and 2-Hydroxy-1-Naphthaldehyde

2002 ◽  
Vol 8 (1) ◽  
pp. 21-26 ◽  
Author(s):  
Narayan T. Akinchan
Keyword(s):  
Chelating Agents ◽  
Spectral Studies ◽  
Mass Spectral ◽  
Metal Chelating ◽  
Derivatives Of

Preparation and Spectroscopic Characterisation of a Series of Heterobimetallic N-phenyldiethanolaminate-alkoxide Derivatives of Oxovanadium(V)

2005 ◽  
Vol 2005 (6) ◽  
pp. 352-355 ◽  
Author(s):  
Rajendra Singh Ghadwal ◽  
Ram C. Mehrotra ◽  
Anirudh Singh
Keyword(s):  
Molecular Weight ◽  
Spectral Studies ◽  
Metal Alkoxides ◽  
Nmr Studies ◽  
Mass Spectral ◽  
Elemental Analyses ◽  
Derivatives Of ◽  
Spectroscopic Characterisation

Reaction of VO(OPri)3 with two equivalents of N-phenyldiethanolamine (PhDEAH2) yields a homometallic complex [VO(PhDEA)(PhDEAH)] 1, which reacts with a number of metal alkoxides to afford heterobimetallic oxovanadium(V) complexes of the types [VO(PhDEA)2{M(OR)n-1}] [where PhDEA = C6H5N(CH2CH2O–)2], [M =: Al (n = 3, R = Pri) 2; Al (n = 3, R = But) 3; Ti (n = 4, R = Pri) 4; Zr (n = 4, R = Pri) 5; Nb (n = 5, R = Pri) 6; Ta (n = 5, R = Pri) 7. The derivative [VO(PhDEA)(OSiPh3)] 8 has been prepared by the equimolar interaction of [VO(PhDEA)(OPri)] with Ph3SiOH. All of these complexes have been characterised by spectroscopic (IR; 1H, 13C, 27Al and 51V NMR) studies, elemental analyses, and molecular weight measurements. The derivative 2 has also been characterised by FAB mass spectral studies, which supports for its monomeric nature.

scholarly journals New oxadiazole derivatives of isonicotinohydrazide in the search for antimicrobial agents: Synthesis and in vitro evaluation

2012 ◽  
Vol 77 (1) ◽  
pp. 9-16 ◽  
Author(s):  
Manav Malhotra ◽  
Mohit Sanduja ◽  
Abdul Samad ◽  
Aakash Deep
Keyword(s):  
Antimicrobial Agents ◽  
Fungal Strain ◽  
Spectral Studies ◽  
Dilution Method ◽  
Mass Spectral ◽  
Oxadiazole Derivatives ◽  
Derivatives Of ◽  
And Staphylococcus Aureus

Structural modification of the front line antitubercular drug isoniazid provide a lipophilic adaptations of the drug in which hydrazide moiety of isoniazid is replaced by 1,3,4-oxadiazole heterocycles to eliminate in-vivo acetylation by arylamine N-acetyltransferase which results to form inactive acetylated drug. In the present study a series of sixteen oxadiazole derivatives were synthesized and characterized by (IR, 1H NMR, 13C NMR and Mass spectral) studies. All the synthesized compounds were evaluated for their antimicrobial activity by broth dilution method against two Gram positive strains (Bacillus subtilis and Staphylococcus aureus), two Gram negative strains (Pseudomonas aeruginosa and Escherichia coli) and fungal strain (Candida albicans and Aspergillus niger). The minimum inhibitory concentration of the compounds was in the range of 1.56-50 ?g ml-1 against bacterial and fungal strain. The results revealed that all synthesized compounds have a significant biological activity against the tested microorganisms. Among the synthesized derivatives 4g, 4h, 4m and 4p were found to be most effective antimicrobial compounds.

Synthesis and antimicrobial properties of N-substituted derivatives of (E)-2′,3″-thiazachalcones

2015 ◽  
Vol 70 (1-2) ◽  
pp. 45-50
Author(s):  
Asu Usta ◽  
Hacer Taşkıran
Keyword(s):  
Elemental Analysis ◽  
Antimicrobial Properties ◽  
Antibacterial Activities ◽  
Spectral Studies ◽  
Gram Negative Bacteria ◽  
Gram Negative ◽  
Mass Spectral ◽  
H Nmr ◽  
Derivatives Of ◽  
C Nmr

Abstract N-alkyl substituted 2′,3″-thiazachalcones {3-[(1E)-3-(4-methylthiophene-2-yl)-3-oxoprop-1-en-1-yl]-1-alkyl (C5–12,14) pyridinium bromides} were synthesized by a two-step reaction. The newly synthesized compounds were characterized by IR, 1H NMR, 13C NMR, elemental analysis and mass spectral studies. The synthesized compounds were tested for antibacterial activities and found to be more active against Gram-positive as compared to Gram-negative bacteria.

Mass spectral studies of some aryl and aroyl derivatives of glyoxime

1974 ◽  
Vol 9 (10) ◽  
pp. 1022-1026 ◽  
Author(s):  
P. B. Terent'ev ◽  
A. N. Kost ◽  
Jerzy Lange
Keyword(s):  
Spectral Studies ◽  
Mass Spectral ◽  
Derivatives Of

scholarly journals Ultrasound-Assisted One Pot Synthesis of Novel 5-(1-(Substituted phenyl)-4,5-diphenyl-1H-imidazol-2-yl)-4-methylthiazole

Proceedings ◽  
2018 ◽  
Vol 9 (1) ◽  
pp. 63
Author(s):  
Nimbalkar ◽  
Seijas ◽  
Vazquez-Tato ◽  
Nikalje
Keyword(s):  
Ammonium Nitrate ◽  
13C Nmr ◽  
Ammonium Acetate ◽  
Ceric Ammonium Nitrate ◽  
Spectral Studies ◽  
One Pot ◽  
Mass Spectral ◽  
Aryl Amines ◽  
Ultrasound Assisted ◽  
Derivatives Of

This work reports synthesis of ten novel derivatives of 5-(1-(substituted phenyl)-4,5-diphenyl-1H-imidazol-2-yl)-4-methylthiazole 5(a–o). The reaction of benzil, primary aryl amines, 4-methylthiazole-5-carbaldehyde and ammonium acetate was carried out in one pot in the presence of eco-friendly catalyst Ceric ammonium nitrate in solvent ethanol to give final compounds. The structures of the synthesized compounds were confirmed by spectral characterization such as IR, 1H-NMR, 13C-NMR and mass spectral studies.

scholarly journals MICROWAVE-ASSISTED SYNTHESIS, CHARACTERIZATION, AND BIOLOGICAL EVALUATION OF PHENYLACRYLAMIDE DERIVATIVES OF TRIAZOLES DERIVED FROM OXAZOLONES

2018 ◽  
Vol 11 (7) ◽  
pp. 285
Author(s):  
Venkat Swamy Puli ◽  
Vukoti Kiran Kumar ◽  
Venkata Reddy Regalla ◽  
Anindita Chatterjee
Keyword(s):  
Antioxidant Activities ◽  
Reaction Times ◽  
Biological Evaluation ◽  
Biologically Active ◽  
Spectral Studies ◽  
Microwave Assisted Synthesis ◽  
Microwave Technology ◽  
Mass Spectral ◽  
Microwave Assisted ◽  
Derivatives Of

Objective: The aim of the present study is to synthesize novel phenylacrylamide derivatives as potent bioactive agents.Methods: Novel N-(3-(4H-1,2,4-triazol-4-ylamino)-3-oxo-1-arylidene prop-2-yl) benzimidic acids (7a-c) have been synthesized by the reaction of 4-(arylidene)-2-phenyloxazol-5(4H)-ones (5a-c) with 4-amino-1, 2, 4-triazole (6) in the presence of anhydrous sodium acetate in glacial acetic acid. Titled compounds (7a-c) were obtained in good yields using microwave technology which resulted in dramatic reductions in reaction times leading to the formation of phenylacrylamide derivatives (7a-c) at a faster rate.Results: The structures of the newly synthesized compounds were characterized by Fourier-transform infrared, 1H NMR, 13C NMR, and mass spectral studies. This method can be an efficient method for the synthesis of phenylacrylamide derivatives (7a-c).Conclusion: All the final compounds were screened for their antimicrobial and antioxidant activities and found to be biologically active. Among all the compounds, 7b was found to be potent antimicrobial and antioxidant.

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