Ranirestat (AS-3201), a Potent Aldose Reductase Inhibitor, Reduces Sorbitol Levels and Improves Motor Nerve Conduction Velocity in Streptozotocin-Diabetic Rats

Takafumi Matsumoto; Yoshiyuki Ono; Masuo Kurono; Akemi Kuromiya; Keiji Nakamura; Vera Bril

doi:10.1254/jphs.08061fp

Ranirestat (AS-3201), a Potent Aldose Reductase Inhibitor, Reduces Sorbitol Levels and Improves Motor Nerve Conduction Velocity in Streptozotocin-Diabetic Rats

Journal of Pharmacological Sciences ◽

10.1254/jphs.08061fp ◽

2008 ◽

Vol 107 (3) ◽

pp. 231-237 ◽

Cited By ~ 28

Author(s):

Takafumi Matsumoto ◽

Yoshiyuki Ono ◽

Masuo Kurono ◽

Akemi Kuromiya ◽

Keiji Nakamura ◽

...

Keyword(s):

Conduction Velocity ◽

Nerve Conduction ◽

Reductase Inhibitor ◽

Nerve Conduction Velocity ◽

Motor Nerve ◽

Diabetic Rats ◽

Aldose Reductase Inhibitor ◽

Motor Nerve Conduction Velocity ◽

Motor Nerve Conduction ◽

Streptozotocin Diabetic Rats

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Effect of a new aldose reductase inhibitor, 8′-chloro-2′,3′-dihydrospiro [pyrrolidine-3,6′(5′H)-pyrrolo[1,2,3,-de] [1,4]bezoxazine]-2,5,5′-trione (ADN-138), on delayed motor nerve conduction velocity in streptozotocin-diabetic rats

Metabolism ◽

10.1016/s0026-0495(98)90011-7 ◽

1988 ◽

Vol 37 (2) ◽

pp. 159-163 ◽

Cited By ~ 15

Author(s):

Yoshihiro Hirata ◽

Shizuyoshi Fujimori ◽

Kodo Okada

Keyword(s):

Conduction Velocity ◽

Nerve Conduction ◽

Reductase Inhibitor ◽

Nerve Conduction Velocity ◽

Motor Nerve ◽

Diabetic Rats ◽

Aldose Reductase Inhibitor ◽

Motor Nerve Conduction Velocity ◽

Motor Nerve Conduction ◽

Streptozotocin Diabetic Rats

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A combination of the aldose reductase inhibitor, statil, and the prostaglandin E1 analogue, OP1206.αCD, completely improves sciatic motor nerve conduction velocity in streptozocin-induced chronically diabetic rats

Metabolism ◽

10.1016/0026-0495(92)90320-a ◽

1992 ◽

Vol 41 (7) ◽

pp. 778-782 ◽

Cited By ~ 3

Author(s):

Hitoshi Yasuda ◽

Masanobu Sonobe ◽

Takashi Hisanaga ◽

Toru Kawabata ◽

Kengo Maeda ◽

...

Keyword(s):

Conduction Velocity ◽

Nerve Conduction ◽

Prostaglandin E1 ◽

Reductase Inhibitor ◽

Nerve Conduction Velocity ◽

Motor Nerve ◽

Diabetic Rats ◽

Aldose Reductase Inhibitor ◽

Motor Nerve Conduction Velocity ◽

Motor Nerve Conduction

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Prevention and reversal of defective axonal transport and motor nerve conduction velocity in rats with experimental diabetes by treatment with the aldose reductase inhibitor Sorbinil

Diabetes ◽

10.2337/diabetes.33.5.470 ◽

1984 ◽

Vol 33 (5) ◽

pp. 470-476 ◽

Cited By ~ 46

Author(s):

D. R. Tomlinson ◽

R. J. Moriarty ◽

J. H. Mayer

Keyword(s):

Axonal Transport ◽

Conduction Velocity ◽

Nerve Conduction ◽

Reductase Inhibitor ◽

Nerve Conduction Velocity ◽

Experimental Diabetes ◽

Motor Nerve ◽

Aldose Reductase Inhibitor ◽

Motor Nerve Conduction Velocity ◽

Motor Nerve Conduction

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Aminoguanidine-effects on endoneurial vasoactive nitric oxide and on motor nerve conduction velocity in control and streptozotocin-diabetic rats

British Journal of Pharmacology ◽

10.1038/sj.bjp.0700946 ◽

1997 ◽

Vol 120 (4) ◽

pp. 593-598 ◽

Cited By ~ 10

Author(s):

M. Dewhurst ◽

N. Omawari ◽

D.R. Tomlinson

Keyword(s):

Nitric Oxide ◽

Conduction Velocity ◽

Nerve Conduction ◽

Nerve Conduction Velocity ◽

Motor Nerve ◽

Diabetic Rats ◽

Motor Nerve Conduction Velocity ◽

Motor Nerve Conduction ◽

Streptozotocin Diabetic Rats

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Prevention and Reversal of Defective Axonal Transport and Motor Nerve Conduction Velocity In Rats with Experimental Diabetes by Treatment with the Aldose Reductase Inhibitor Sorbinil

Diabetes ◽

10.2337/diab.33.5.470 ◽

1984 ◽

Vol 33 (5) ◽

pp. 470-476 ◽

Cited By ~ 57

Author(s):

D. R. Tomlinson ◽

R. J. Moriarty ◽

J. H. Mayer

Keyword(s):

Axonal Transport ◽

Conduction Velocity ◽

Nerve Conduction ◽

Reductase Inhibitor ◽

Nerve Conduction Velocity ◽

Experimental Diabetes ◽

Motor Nerve ◽

Aldose Reductase Inhibitor ◽

Motor Nerve Conduction Velocity ◽

Motor Nerve Conduction

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Relation of Na+, K+-ATPase to delayed motor nerve conduction velocity: Effect of aldose reductase inhibitor, ADN-138, on Na+, K+-ATPase activity

Metabolism ◽

10.1016/0026-0495(90)90019-9 ◽

1990 ◽

Vol 39 (6) ◽

pp. 563-567 ◽

Cited By ~ 18

Author(s):

Yoshihiro Hirata ◽

Kodo Okada

Keyword(s):

Atpase Activity ◽

Conduction Velocity ◽

Nerve Conduction ◽

Reductase Inhibitor ◽

Nerve Conduction Velocity ◽

Motor Nerve ◽

Aldose Reductase Inhibitor ◽

Motor Nerve Conduction Velocity ◽

Motor Nerve Conduction ◽

Velocity Effect

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Effects of a new aldose reductase inhibitor, (2S, 4S)-6-fluoro-2′,5′-dioxospiro[chroman-4,4′-imidazolidine]-2-carboxamide (SNK-860), on the slowing of motor nerve conduction velocity and metabolic abnormalities in the peripheral nerve in acute streptozotocin-induced diabetic rats

Metabolism ◽

10.1016/0026-0495(92)90289-m ◽

1992 ◽

Vol 41 (10) ◽

pp. 1081-1086 ◽

Cited By ~ 33

Author(s):

Kuniharu Mizuno ◽

Noriaki Kato ◽

Akira Matsubara ◽

Kazumasa Nakano ◽

Masayasu Kurono

Keyword(s):

Peripheral Nerve ◽

Nerve Conduction ◽

Reductase Inhibitor ◽

Nerve Conduction Velocity ◽

Motor Nerve ◽

Diabetic Rats ◽

Aldose Reductase Inhibitor ◽

Motor Nerve Conduction Velocity ◽

Metabolic Abnormalities ◽

Motor Nerve Conduction

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The Effect of Aldose Reductase Inhibition on Motor Nerve Conduction Velocity in Diabetic Rats

Diabetes ◽

10.2337/diab.31.9.789 ◽

1982 ◽

Vol 31 (9) ◽

pp. 789-794 ◽

Cited By ~ 61

Author(s):

D. K. Yue ◽

M. A. Hanwell ◽

P. M. Satchell ◽

J. R. Turtle

Keyword(s):

Conduction Velocity ◽

Aldose Reductase ◽

Nerve Conduction ◽

Nerve Conduction Velocity ◽

Motor Nerve ◽

Diabetic Rats ◽

Motor Nerve Conduction Velocity ◽

Motor Nerve Conduction ◽

Aldose Reductase Inhibition

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A new prostaglandin E1 analogue (TFC-612) prevents a decrease in motor nerve conduction velocity in streptozocin-diabetic rats

Biochemical and Biophysical Research Communications ◽

10.1016/0006-291x(88)90509-8 ◽

1988 ◽

Vol 150 (1) ◽

pp. 225-230 ◽

Cited By ~ 21

Author(s):

Hitoshi Yasuda ◽

Masanobu Sonobe ◽

Ikuo Hatanaka ◽

Makio Yamashita ◽

Yasufumi Miyamoto ◽

...

Keyword(s):

Conduction Velocity ◽

Nerve Conduction ◽

Prostaglandin E1 ◽

Nerve Conduction Velocity ◽

Motor Nerve ◽

Diabetic Rats ◽

Motor Nerve Conduction Velocity ◽

Motor Nerve Conduction

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Improvement of Motor Nerve Conduction Velocity in Diabetic Rats Requires Normalization of the Polyol Pathway Metabolites Flux

Journal of Pharmacological Sciences ◽

10.1254/jphs.08177fp ◽

2009 ◽

Vol 109 (2) ◽

pp. 203-210 ◽

Cited By ~ 6

Author(s):

Takafumi Matsumoto ◽

Yoshiyuki Ono ◽

Masuo Kurono ◽

Akemi Kuromiya ◽

Keiji Nakamura ◽

...

Keyword(s):

Conduction Velocity ◽

Nerve Conduction ◽

Nerve Conduction Velocity ◽

Motor Nerve ◽

Polyol Pathway ◽

Diabetic Rats ◽

Motor Nerve Conduction Velocity ◽

Motor Nerve Conduction

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