scholarly journals Immunomodulating Activity of Ginsenoside Rg1 from Panax Ginseng

1990 ◽  
Vol 54 (4) ◽  
pp. 447-454 ◽  
Author(s):  
Buriana KENAROVA ◽  
Hristo NEYCHEV ◽  
Christina HADJIIVANOVA ◽  
Vesselin D. PETKOV
Keyword(s):  
Panax Ginseng ◽  
Ginsenoside Rg1 ◽  
Immunomodulating Activity

scholarly journals Panax ginseng Modulates Cytokines in Bone Marrow Toxicity and Myelopoiesis: Ginsenoside Rg1 Partially Supports Myelopoiesis

PLoS ONE ◽  
2012 ◽  
Vol 7 (4) ◽  
pp. e33733 ◽  
Author(s):  
Hanumantha Rao Balaji Raghavendran ◽  
Rekha Sathyanath ◽  
JangWoo Shin ◽  
Hyeong Keug Kim ◽  
Jong Min Han ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Panax Ginseng ◽  
Bone Marrow Toxicity ◽  
Ginsenoside Rg1

scholarly journals Deciphering the transcriptomic response of Ilyonectria robusta in relation to Ginsenoside Rg1 treatment and the development of panax ginseng rusted root disease

2019 ◽  
Author(s):  
Qiong Li ◽  
Yonghua Xu ◽  
Lianxue Zhang ◽  
Peng Di ◽  
Baohui Lu ◽  
...  
Keyword(s):  
Panax Ginseng ◽  
Ginseng Root ◽  
Ginsenoside Rg1 ◽  
Fungal Cell ◽  
Transcriptomic Response ◽  
Disease Symptoms ◽  
Expression Of Genes ◽  
Ginsenoside Content ◽  
Severity Of The Disease

Abstract Rust rot is a severe Panax ginseng disease caused by Ilyonectria robusta . The severity of the disease is related to the content of residual ginsenoside content in the soil. Herein, the effects of different concentrations of ginsenoside Rg1 on ginseng rust rot and its pathogens were studied, and the growth and sporulation of fungi cultured in vitro were determined. The results showed that Rg1 significantly promoted the mycelial growth, and sporulation compared to the control, and aggravated the disease symptoms of Panax ginseng . A total of 6,708 transcripts out of 213,131 annotated genes identified from global transcriptomic analysis were differentially expressed in I.robusta grown in the Rg1 treatment. These genes were found to be related to the carbon-nitrogen metabolism, transport, and assimilation. Many of these genes were also associated with pathogenicity based on the Phi-base database. Several transcription factors were related to specific biological processes, such as nitrogen utilization. The current results revelation that Rg1 plays a major role in the development of rust rot by promoting fungal cell growth and affecting the expression of genes required for pathogenesis. Rg1 could aggravate the invasion of I.robusta on ginseng root, which preliminarily revealed the reason for the aggravation of rust rot in ginseng c ontinuous cropping obstacle.

Ginsenoside-Rg1, one of the major active molecules from Panax ginseng, is a functional ligand of glucocorticoid receptor

1997 ◽  
Vol 133 (2) ◽  
pp. 135-140 ◽  
Author(s):  
YoungJoo Lee ◽  
Eunah Chung ◽  
Kwang Youl Lee ◽  
Yong Hee Lee ◽  
Bin Huh ◽  
...  
Keyword(s):  
Glucocorticoid Receptor ◽  
Panax Ginseng ◽  
Ginsenoside Rg1

Stability of angiogenic agents, ginsenoside Rg1 and Re, isolated from Panax ginseng: In vitro and in vivo studies

2007 ◽  
Vol 328 (2) ◽  
pp. 168-176 ◽  
Author(s):  
Lin-Chien Yu ◽  
Sung-Ching Chen ◽  
Wei-Chun Chang ◽  
Ya-Chun Huang ◽  
Kurt M. Lin ◽  
...  
Keyword(s):  
Panax Ginseng ◽  
In Vivo Studies ◽  
Ginsenoside Rg1

Angiogenic evaluation of ginsenoside Rg1 from Panax ginseng in fluorescent transgenic mice

2008 ◽  
Vol 49 (1) ◽  
pp. 37-43 ◽  
Author(s):  
Kurt Ming-Chao Lin ◽  
Ching-Han Hsu ◽  
Subbiah Rajasekaran
Keyword(s):  
Transgenic Mice ◽  
Panax Ginseng ◽  
Ginsenoside Rg1

Effects of Ginsenoside Rg1 of Panax Ginseng on Mitosis in Human Blood Lymphocytes in Vitro

1980 ◽  
Vol 08 (03) ◽  
pp. 254-267 ◽  
Author(s):  
Lan-sang Tong ◽  
Chuan-ying Chao
Keyword(s):  
Dna Synthesis ◽  
Panax Ginseng ◽  
Human Lymphocytes ◽  
Resting Cells ◽  
Ginsenoside Rg1 ◽  
Con A ◽  
Pharmacological Significance ◽  
Treated Culture ◽  
Mitogenic Lectin

The ginsenoside Rg1 extracted from the root of Panax ginseng can promote mitosis in cultured human lymphocytes activated by PHA or Con A. Its most effective concentrations are around 0.0003-0.0005 mg per ml of medium. Experiments shows that its does not arrest the cells at any particular mitotic stage. It can also enhance the DNA synthesis in the activated lymphocytes. As a result of the increased number of mitotic cells and enhanced DNA synthesis, the cell density is significantly increased in the Rg1-treated culture as compared with the control. However, in the absence of a mitogenic lectin, Rg1 cannot restart the quinescent human lymphocytes to divide in vitro; therefore it is not mitogenic to resting cells. The possible action Rg1 on activated human lymphocytes as well as its pharmacological significance are discussed.

scholarly journals Ginsenoside Rg1 from Panax ginseng enhances myoblast differentiation and myotube growth

2017 ◽  
Vol 41 (4) ◽  
pp. 608-614 ◽  
Author(s):  
Ga-Yeon Go ◽  
Sang-Jin Lee ◽  
Ayoung Jo ◽  
Jaecheol Lee ◽  
Dong-Wan Seo ◽  
...  
Keyword(s):  
Panax Ginseng ◽  
Myoblast Differentiation ◽  
Ginsenoside Rg1

Enhancement of ginsenoside Rg1 in Panax ginseng hairy root by overexpressing the α-l-rhamnosidase gene from Bifidobacterium breve

2015 ◽  
Vol 37 (10) ◽  
pp. 2091-2096 ◽  
Author(s):  
Ru Zhang ◽  
Bian-Ling Zhang ◽  
Gu-Cai Li ◽  
Tao Xie ◽  
Teng Hu ◽  
...  
Keyword(s):  
Panax Ginseng ◽  
Hairy Root ◽  
Ginsenoside Rg1 ◽  
Bifidobacterium Breve
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