Inhibition of Angiotensin Converting Enzyme by (R)-3-[(S)-1-Carboxy-5-(4-Piperidyl)pentyl]amino-4-Oxo-2,3,4,5-Tetrahydro-1,5-Benzothiazepine-5-Acetic Acid (CV-5975), a Non-Sulfhydryl Compound

Yoshiyuki INADA; Masao TANABE; Katsumi ITOH; Hirosada SUGIHARA; Kohei NISHIKAWA

doi:10.1254/jjp.48.323

Inhibition of Angiotensin Converting Enzyme by (R)-3-[(S)-1-Carboxy-5-(4-Piperidyl)pentyl]amino-4-Oxo-2,3,4,5-Tetrahydro-1,5-Benzothiazepine-5-Acetic Acid (CV-5975), a Non-Sulfhydryl Compound

The Japanese Journal of Pharmacology ◽

10.1254/jjp.48.323 ◽

1988 ◽

Vol 48 (3) ◽

pp. 323-330 ◽

Cited By ~ 7

Author(s):

Yoshiyuki INADA ◽

Masao TANABE ◽

Katsumi ITOH ◽

Hirosada SUGIHARA ◽

Kohei NISHIKAWA

Keyword(s):

Acetic Acid ◽

Angiotensin Converting Enzyme ◽

Converting Enzyme ◽

Sulfhydryl Compound

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Antihypertensive action of a new angiotensin converting enzyme inhibitor, (R)-3-((S)-1-carboxy-5-(4-piperidyl)pentyl)amino-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepine-5-acetic acid (CV-5975), in various hypertensive models.

The Japanese Journal of Pharmacology ◽

10.1254/jjp.47.311 ◽

1988 ◽

Vol 47 (3) ◽

pp. 311-322 ◽

Cited By ~ 8

Author(s):

Yoshiyuki INADA ◽

Masao TANABE ◽

Katsuyoshi KAWAZOE ◽

Kohei NISHIKAWA

Keyword(s):

Acetic Acid ◽

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor ◽

Antihypertensive Action

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(R)-3-((S)-1-carboxy-5-(4-piperidyl)pentyl)amino-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepine-5-acetic acid (CV-5975): A new potent and long-lasting inhibitor of angiotensin converting enzyme.

The Japanese Journal of Pharmacology ◽

10.1254/jjp.47.135 ◽

1988 ◽

Vol 47 (2) ◽

pp. 135-141 ◽

Cited By ~ 21

Author(s):

Yoshiyuki INADA ◽

Katsumi ITOH ◽

Kazuhide KAMIYA ◽

Hirosada SUGIHARA ◽

Kohei NISHIKAWA

Keyword(s):

Acetic Acid ◽

Angiotensin Converting Enzyme ◽

Converting Enzyme

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Antihypertensive Action of a New Angiotensin Converting Enzyme Inhibitor, (R)-3-[(S)-1-Carboxy-5-(4-Piperidyl)pentyl]amino-4-Oxo-2,3,4,5-Tetrahydro-1,5-Benzothiazepine-5-Acetic Acid (CV-5975), in Various Hypertensive Models

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)43215-0 ◽

1988 ◽

Vol 47 (3) ◽

pp. 311-322

Author(s):

Yoshiyuki INADA ◽

Masao TANABE ◽

Katsuyoshi KAWAZOE ◽

Kohei NISHIKAWA

Keyword(s):

Acetic Acid ◽

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor ◽

Antihypertensive Action

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Inhibition of Angiotensin Converting Enzyme by CV-3317, a Non-Sulfhydryl Compound

The Japanese Journal of Pharmacology ◽

10.1254/jjp.42.99 ◽

1986 ◽

Vol 42 (1) ◽

pp. 99-108 ◽

Cited By ~ 24

Author(s):

Yoshiyuki INADA ◽

Zen-ichi TERASHITA ◽

Yoshimi IMURA ◽

Masao TANABE ◽

Kohei NISHIKAWA ◽

...

Keyword(s):

Angiotensin Converting Enzyme ◽

Converting Enzyme ◽

Sulfhydryl Compound

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(R)-3-[(S)-1-Carboxy-5-(4-Piperidyl)pentyl]amino-4-Oxo-2,3,4,5-Tetrahydro-1,5-Benzothiazepine-5-Acetic Acid (CV-5975): A New Potent and Long-Lasting Inhibitor of Angiotensin Converting Enzyme

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)43227-7 ◽

1988 ◽

Vol 47 (2) ◽

pp. 135-141

Author(s):

Yoshiyuki INADA ◽

Katsumi ITOH ◽

Kazuhide KAMIYA ◽

Hirosada SUGIHARA ◽

Kohei NISHIKAWA

Keyword(s):

Acetic Acid ◽

Angiotensin Converting Enzyme ◽

Converting Enzyme

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Significance Of Exaggerated Natriuresis After Angiotensin AT1 Receptor Blockade Or Angiotensin- Converting Enzyme Inhibition In Obese Zucker Rats

Clinical and Experimental Pharmacology and Physiology ◽

10.1046/j.1440-1681.2001.3457.x ◽

2001 ◽

Vol 28 (5-6) ◽

pp. 433-440 ◽

Cited By ~ 1

Author(s):

Lakshmi S Tallam ◽

Bhagavan S Jandhyala

Keyword(s):

Angiotensin Converting Enzyme ◽

Enzyme Inhibition ◽

At1 Receptor ◽

Zucker Rats ◽

Angiotensin Converting Enzyme Inhibition ◽

Receptor Blockade ◽

Converting Enzyme ◽

Converting Enzyme Inhibition ◽

Obese Zucker Rats

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Angiotensin-Converting Enzyme Inhibitor-Associated Angioedema

Allergy & Clinical Immunology International - Journal of the World Allergy Organization ◽

10.1027/0838-1925.19.4.164 ◽

2007 ◽

Vol 19 (4) ◽

pp. 164-165

Author(s):

Byol Shin ◽

Richard Lockey

Keyword(s):

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor

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P3438 Angiotensin converting enzyme polymorphism determines differential acumulation of cardiac extracelular matrix protein induced by isoproterenol in the rat

European Heart Journal ◽

10.1016/s0195-668x(03)96064-7 ◽

2003 ◽

Vol 24 (5) ◽

pp. 664

Author(s):

M OCARANZA

Keyword(s):

Angiotensin Converting Enzyme ◽

Matrix Protein ◽

Enzyme Polymorphism ◽

Converting Enzyme

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P3402 Anti-ischaemic effect of angiotensin-converting enzyme inhibitor, but not vitamin C in patients with coronary artery disease treated with beta-blockers and nitrates. Randomised, cross-over double-blind comparison

European Heart Journal ◽

10.1016/s0195-668x(03)96028-3 ◽

2003 ◽

Vol 24 (5) ◽

pp. 655

Author(s):

R DABROWSKI

Keyword(s):

Coronary Artery Disease ◽

Coronary Artery ◽

Vitamin C ◽

Angiotensin Converting Enzyme ◽

Enzyme Inhibitor ◽

Beta Blockers ◽

Converting Enzyme ◽

Double Blind ◽

Artery Disease ◽

Blind Comparison

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3644 Pleiotropic effect of angiotensin-converting enzyme inhibitors on MMP-9: a key enzyme in cardiac and vascular remodelling

European Heart Journal ◽

10.1016/s0195-668x(03)96228-2 ◽

2003 ◽

Vol 24 (5) ◽

pp. 711

Author(s):

D REINHARDT

Keyword(s):

Angiotensin Converting Enzyme ◽

Enzyme Inhibitors ◽

Angiotensin Converting Enzyme Inhibitors ◽

Pleiotropic Effect ◽

Converting Enzyme ◽

Vascular Remodelling ◽

Converting Enzyme Inhibitors ◽

Key Enzyme

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