scholarly journals Biological Activities of Optical Isomers of 6-Chloro-5-Cyclohexylindan-1-Carboxylic Acid (Tai-284: Anti-Inflammatory Agent)

1974 ◽  
Vol 24 (5) ◽  
pp. 695-705 ◽  
Author(s):  
Seiji Kuzuna ◽  
Naohiko Matsumoto ◽  
Tadahiko Kometani ◽  
Kiyohisa Kawai
Keyword(s):  
Carboxylic Acid ◽  
Biological Activities ◽  
Optical Isomers ◽  
Inflammatory Agent ◽  
Anti Inflammatory

Synthesis and biological activities of a nitro-shiff base compound as a potential anti-inflammatory agent

2020 ◽  
Vol 148 ◽  
pp. 105300
Author(s):  
Beatriz Cardoso Roriz ◽  
Danieli Fernanda Buccini ◽  
Beatriz Fuzinato dos Santos ◽  
Suellen Rolon de Sousa Silva ◽  
Nelson Luís de Campos Domingues ◽  
...  
Keyword(s):  
Biological Activities ◽  
Inflammatory Agent ◽  
Shiff Base ◽  
Anti Inflammatory ◽  
Base Compound

Biochemical and biological activities of 2,3-dihydro-6-[3-(2-hydroxymethyl)phenyl-2-propenyl]-5-benzofuranol (L-651,896), a novel topical anti-inflammatory agent

1987 ◽  
Vol 36 (22) ◽  
pp. 3885-3891 ◽  
Author(s):  
Robert J. Bonney ◽  
Phillip Davies ◽  
Harry Dougherty ◽  
Robert W. Egan ◽  
Paul H. Gale ◽  
...  
Keyword(s):  
Biological Activities ◽  
Inflammatory Agent ◽  
Anti Inflammatory

scholarly journals Investigation of Anti-inflammatory activity of Hemedesmus indicus L. on Carrageenan induced paw oedema in rats

2018 ◽  
Vol 8 (5) ◽  
pp. 492-494
Author(s):  
Javed Khan Pathan ◽  
Girendra Gautam ◽  
Arun Kumar Gupta
Keyword(s):  
Biological Activities ◽  
Ethanolic Extract ◽  
Inflammatory Activity ◽  
Hemidesmus Indicus ◽  
Inflammatory Agent ◽  
Climbing Plant ◽  
Inflammatory Models ◽  
Paw Oedema ◽  
Anti Inflammatory ◽  
Dose Dependent

Hemidesmus indicus L. (Family: Apocynaceae), is commonly referred as Indian sarsaparilla, Anantamool or Nannari, commonly available perennial climbing plant had been widely used for its reported biological activities in indigenous system of medicine. The present investigation was carried out to find the effect of aqueous and ethanolic extract of leaves and stem of Hemidesmus indicus for its anti-inflammatory activity. The anti-inflammatory activity was evaluated using acute inflammatory models viz., carrageenan induced paw oedema. Oral administration of the extract at the doses 200 and 400 mg/kg b.w. exhibited dose dependent and significant anti-inflammatory activity in (p < 0.05). Hence, present investigation established pharmacological evidences to support the folklore claim that Hemidesmus indicus is used as anti-inflammatory agent. Keywords: Hemidesmus indicus (H. indicus), Leaves, Stem, Anti-inflammatory activity

scholarly journals Anti-Inflammatory Activity of Dried Ginger Mediated Iron Nanoparticles

2020 ◽  
pp. 14-19
Author(s):  
Sai Sree Lasya Ganta ◽  
M. Jeevitha ◽  
S. Preetha ◽  
S. Rajeshkumar
Keyword(s):  
Iron Nanoparticles ◽  
Size Range ◽  
Catalytic Properties ◽  
Inflammatory Diseases ◽  
Biological Activities ◽  
Inflammatory Activity ◽  
Inflammatory Agent ◽  
Vis Spectroscopy ◽  
Anti Inflammatory ◽  
Inflammatory Effect

Nanotechnology is a branch of science and technology relating to the matter on the atomic and molecular scale in the size range between 1-100 nm. Iron nanoparticles have diverse diagnostic and potential therapeutic applications with unique magnetic and catalytic properties and potent biological activities. The present study aimed to analyse the anti-inflammatory activity of iron nanoparticles synthesized from dried ginger. The synthesized iron nanoparticles were characterized using UV-vis spectroscopy and evaluated for anti-inflammatory activity by inhibition of albumin denaturation assay. The nanoparticles showed maximum absorbance at 360 nm and revealed potent anti-inflammatory effect with maximum of 83.5% inhibition at lowest concentration of 50 µl and thus can be used as an anti-inflammatory agent in various inflammatory diseases.

scholarly journals Technological prospection of anti-inflammatory vanilic acid activity, with emphasis on its semisynthetic derivative Isopropyl Vanilate

2021 ◽  
Vol 10 (3) ◽  
pp. e35910313451
Author(s):  
Kerolayne Melo Nogueira ◽  
Luan Kelves Miranda de Souza ◽  
Jand Venes Rolim Medeiros
Keyword(s):  
Vanillic Acid ◽  
Biological Activities ◽  
Inflammatory Agent ◽  
International Patent ◽  
Search Field ◽  
Synthetic Derivative ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Semisynthetic Derivative ◽  
Vanilic Acid

Inflammation is the body's response to harmful stimuli such as infections, trauma, or injury. The inflammatory cascade can lead to the development of numerous diseases, and the current drug-therapeutic intervention consists of the use of corticosteroids and non-steroidal anti-inflammatory drugs. However, the use of these is associated with several serious side effects, so it is necessary to search for new alternatives that can minimize this effect. In this prospecting, the objective was to conduct a study on biological activities already described for vanillic acid, with special emphasis on its semi-synthetic derivative of isopropyl vanylate as an anti-inflammatory agent. For this, information was obtained on patent documents based on the INPI, USPTO and EPO databases, using the keywords: vanillic acid, anti-inflammatory agents, isopropyl vanylate, always used in the search field related to the summary of works. As results obtained in the present technological prospection study, it was found that in the international patent databases the documents related to the theme were very scarce and some had a higher number of patents, on vanillic acid, few refer to its anti- inflammatory, and no documents were found on the use of isopropyl vanillate as an anti-inflammatory agent, reinforcing the innovative character of research involving its use in this technology.

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