scholarly journals THE CENTRAL EFFECTS OF ADRENALINE AND NORADRENALINE ON THE BLOOD PRESSURE IN DOG

1962 ◽  
Vol 12 (2) ◽  
pp. 120-129 ◽  
Author(s):  
SHUNJI TACHI
Keyword(s):  
Blood Pressure ◽  
Central Effects

CENTRAL EFFECTS OF ARGININE VASOPRESSIN ON BLOOD PRESSURE IN RATS

Endocrinology ◽  
1982 ◽  
Vol 110 (3) ◽  
pp. 1058-1060 ◽  
Author(s):  
QUENTIN J. PITTMAN ◽  
DUNCAN LAWRENCE ◽  
LYNN McLEAN
Keyword(s):  
Blood Pressure ◽  
Arginine Vasopressin ◽  
Central Effects

Reserpine-induced central effects: pharmacological evidence for the lack of central effects of reserpine methiodide

2005 ◽  
Vol 83 (6) ◽  
pp. 509-515 ◽  
Author(s):  
Srinivas Nammi ◽  
Krishna Murthy Boini ◽  
Sushruta Koppula ◽  
Satyanarayana Sreemantula
Keyword(s):  
Blood Pressure ◽  
Central Nervous System ◽  
Nervous System ◽  
Target Tissue ◽  
Central Effects ◽  
Anaesthetized Rats ◽  
The Central Nervous System ◽  
Rats And Mice ◽  
Dose Dependent ◽  
Higher Doses

Reserpine, an alkaloid from Rauwolfia serpentina, was widely used for its antihypertensive action. However, its use has been reduced because of its sedative and extra pyramidal symptoms. In the present investigation, reserpine methiodide (RMI), a quaternary analogue of reserpine, was synthesized and pharmacologically evaluated in rats and mice for its central (barbiturate hypnosis, spontaneous motor activity, body temperature, and avoidance of conditioned response) and peripheral actions (blood pressure) in comparison with reserpine. The results indicate that reserpine produced a dose-dependent depression of the central nervous system. RMI at doses equal to and double the equimolar doses of reserpine did not produce any behavioural changes compared with control animals. Nevertheless, both reserpine and RMI were found to produce dose-dependent reduction in the blood pressure of anaesthetized rats, although only at higher doses of RMI, indicating that quaternization of reserpine not only attenuated the entry of RMI into the central nervous system, but also reduced its access to the target tissue in the periphery. It is speculated that the hypotensive actions of RMI may also be due to peripheral depletion of catecholamines. Key words: resperine methiodide (RMI), reserpine, behaviour, blood pressure, mice, rats.

scholarly journals Peripheral and Central Effects of Melatonin on Blood Pressure Regulation

2014 ◽  
Vol 15 (10) ◽  
pp. 17920-17937 ◽  
Author(s):  
Olga Pechanova ◽  
Ludovit Paulis ◽  
Fedor Simko
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Regulation ◽  
Pressure Regulation ◽  
Central Effects

Central Effects of Interleukin-1 on Blood Pressure, Thermogenesis, and the Release of Vasopressin, ACTH, and Atrial Natriuretic Peptide

1993 ◽  
Vol 689 (1 The Neurohypo) ◽  
pp. 330-345 ◽  
Author(s):  
TOKIHISA KIMURA ◽  
TADASU YAMAMOTO ◽  
KOZO OTA ◽  
MASARU SHOJI ◽  
MINORU INOUE ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Atrial Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Interleukin 1 ◽  
Central Effects ◽  
Atrial Natriuretic

Central effects of angiotensins on drinking and blood pressure: Structure-activity relationships

1982 ◽  
Vol 236 (2) ◽  
pp. 417-428 ◽  
Author(s):  
J.A.D.M. Tonnaer ◽  
V.M. Wiegant ◽  
W. De Jong ◽  
D. De Wied
Keyword(s):  
Blood Pressure ◽  
Central Effects ◽  
Structure Activity Relationships ◽  
Structure Activity
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