scholarly journals Effects of 1-hydroxyethylidene-1, 1-bisphosphonate (HEBP) on the unimpeded eruption rate and the dental hard tissue formation in rat mandibular incisor.

1989 ◽  
Vol 93 (2) ◽  
pp. 75-87 ◽  
Author(s):  
Takayuki IZUMI
Keyword(s):  
Tissue Formation ◽  
Hard Tissue ◽  
Mandibular Incisor ◽  
Eruption Rate ◽  
Dental Hard Tissue

scholarly journals 4-Hexylresorcinol Administration Increases Dental Hard Tissue Formation and Incisor Eruption Rate in Rats

2020 ◽  
Vol 10 (16) ◽  
pp. 5511 ◽  
Author(s):  
Ji-Hwan Kim ◽  
Dae-Won Kim ◽  
Seong-Gon Kim ◽  
Tae-Woo Kim
Keyword(s):  
Bone Turnover ◽  
Western Blotting ◽  
Immunohistochemical Staining ◽  
Tissue Formation ◽  
Hard Tissue ◽  
Tissue Samples ◽  
Mandibular Incisor ◽  
Eruption Rate ◽  
Dental Hard Tissue ◽  
Tgf Β1

Dental hard tissue formation and bone turnover are required for tooth eruption. 4-Hexylresorcinol (4HR) accelerates tooth movement by increasing bone turnover in orthodontic treatment. This study aimed to evaluate the following: (1) the effect of 4HR application on the expression of proteins associated with tooth formation, and (2) the effect of 4HR application on mandibular incisor eruption rate in a rat model. Primary cultured pulp cells received either 4HR (1 to 100 µM) or solvent only; western blotting was performed for transforming growth factor-beta 1 (TGF-β1), bone morphogenic protein-2/4 (BMP-2/4), runt-related transcription factor 2 (Runx2), osterix (OSX), dentin sialophosphoprotein (DSPP), and parathyroid hormone-related protein receptor (PTHrP-R). In in vivo study, rats (15 males and 15 females) received either solvent or 0.128 mg/kg or 12.8 mg/kg of 4HR via subcutaneous injection; mandibular incisor eruption rate was subsequently recorded. Immunohistochemical staining and western blotting for TGF-β1, BMP-2/4, Runx2, OSX, DSPP, and PTHrP-R were performed in the mandibular tissue samples. 4HR administration was found to increase TGF-β1, BMP-2/4, Runx2, OSX, DSPP, and PTHrP-R expression in both cell culture and tissue samples. Immunohistochemical staining of some markers showed site-specific expression, thereby indicating programmed differentiation of odontoblasts and ameloblasts. The eruption rate was significantly higher in the 12.8 mg/kg 4HR-administered group than in the untreated control (p = 0.001 and 0.010 for males and females, respectively). Collectively, 4HR administration increased the expression of markers related to dental hard tissue formation and accelerated the eruption rate of incisors in rats.

The action of acute doses of fluoride on serum calcium level in relation to dental hard tissue formation in rats

1976 ◽  
Vol 22 (S1) ◽  
pp. 454-457 ◽  
Author(s):  
M. Joostlarsen ◽  
O. Fejerskov ◽  
K. Josephsen ◽  
L. Hammarström
Keyword(s):  
Serum Calcium ◽  
Calcium Level ◽  
Serum Calcium Level ◽  
Tissue Formation ◽  
Hard Tissue ◽  
Dental Hard Tissue

Combined effect of fluoride and 2,3,7,8-tetrachlorodibenzo-p-dioxin on mouse dental hard tissue formation in vitro

2010 ◽  
Vol 85 (8) ◽  
pp. 953-963 ◽  
Author(s):  
Eija Salmela ◽  
Pirjo-Liisa Lukinmaa ◽  
Anna-Maija Partanen ◽  
Carin Sahlberg ◽  
Satu Alaluusua
Keyword(s):  
Combined Effect ◽  
Tissue Formation ◽  
Hard Tissue ◽  
Dental Hard Tissue ◽  
Tetrachlorodibenzo P Dioxin

Effects of 2,4-dichlorophenoxy acetic acid dimethyl amine salt on dental hard tissue formation in rats

2001 ◽  
Vol 26 (3) ◽  
pp. 137-142 ◽  
Author(s):  
Ali Riza Alpöz ◽  
Necip Tosun ◽  
Cemal Eronat ◽  
Nafiz Delen ◽  
Bilge Hakan Şen
Keyword(s):  
Acetic Acid ◽  
Amine Salt ◽  
Tissue Formation ◽  
Hard Tissue ◽  
Dental Hard Tissue ◽  
Dimethyl Amine ◽  
Dichlorophenoxy Acetic Acid

Atypical hard tissue formation around multiple teeth

2011 ◽  
Vol 111 (2) ◽  
pp. 138-145 ◽  
Author(s):  
Valerie G.A. Suter ◽  
Peter A. Reichart ◽  
Dieter D. Bosshardt ◽  
Michael M. Bornstein
Keyword(s):  
Tissue Formation ◽  
Hard Tissue

Tooth development in the ‘crooked’ mouse

Development ◽  
1977 ◽  
Vol 41 (1) ◽  
pp. 279-287
Author(s):  
J. A. Sofaer
Keyword(s):  
Competitive Inhibition ◽  
Tooth Development ◽  
Tooth Germ ◽  
Axial Skeleton ◽  
Tissue Formation ◽  
Supernumerary Teeth ◽  
Hard Tissue ◽  
Dental Lamina ◽  
Dental Abnormalities ◽  
Rates Of Growth

The semidominant gene ‘crooked’ (Cd) in the mouse produces anomalies of the axial skeleton (resulting in a crooked tail), microphthalmia and dental abnormalities, including small molars with simplified cusp patterns that are equivalent to patterns passed through during normal morphodifferentiation. A series of embryonic litters from Cd/ + × Cd / + matings was used to investigate the embryological basis for the dental abnormalities. Microphthalmic embryos were classed as Cd/Cd, and their most normal litter mates were selected as controls (+ / + or Cd / +). An additional set of control embryos came from the inbred strain CBA/Cam (+ / +). Serial sagittal sections of the heads of these embryos were examined microscopically, and the maximum anteroposterior diameters of the developing upper and lower first molars were measured. Reduction in the rates of growth and morphodifferentiation of Cd/Cd first molars, relative to those of litter mate controls, was associated with the appearance of an adjacent abnormal proliferation of the dental lamina. Some proliferations in older embryos showed signs of early tooth germ formation, but many were seen to have regressed and no examples of supernumerary teeth have been found in Cd/Cd adults. Small size of Cd/Cd molars may therefore result from competitive inhibition of molar growth by a transient abnormal laminal proliferation, and Cd/Cd cusp patterns from the relatively premature onset of hard tissue formation during normal but retarded sequences of morphodifferentiation.

Scanning ablation of dental hard tissue with Erbium laser radiation

1996 ◽  
Author(s):  
M. Zeck ◽  
Hartmut Benthin ◽  
Thomas P. Ertl ◽  
G. K. Siebert ◽  
Gerhard J. Mueller
Keyword(s):  
Laser Radiation ◽  
Hard Tissue ◽  
Erbium Laser ◽  
Dental Hard Tissue

scholarly journals Apexification Using Mineral Trioxide Aggregate and Modified Internal Matrix: A Case Report

2021 ◽  
Vol 33 (2) ◽  
Keyword(s):  
Case Report ◽  
Mineral Trioxide Aggregate ◽  
Tissue Formation ◽  
Enamel Hypoplasia ◽  
Hard Tissue ◽  
Radiographic Evidence ◽  
Radiographic Findings ◽  
Immature Teeth ◽  
Patient Reported ◽  
Treatment Alternatives

When pulpal necrosis occurs in immature teeth, one of the treatment alternatives is the creation of an artificial apical barrier through the placement of an apical plug. However, controlling the mineral trioxide aggregate (MTA) during placement has proven difficult. Several studies evaluated the use of resorbable barriers to act as an internal matrix to prevent accidental extrusion of MTA. The aim of this case report was to document the effectiveness of Surgicel as a modified internal matrix for proper placement of MTA during management of immature teeth with necrotic pulp using the apical plug technique. A 12-year-old female patient reported with the chief complaint of a badly mutilated lower right second premolar. The tooth suffered enamel hypoplasia and had a defective coronal structure. It was asymptomatic except for slight tenderness to percussion. Based on the clinical and radiographic findings, a diagnosis of pulpal necrosis with symptomatic apical periodontitis was made. The 3- and 6-month followup showed radiographic evidence of continued root and hard tissue formation. Based on these findings, we infer that Surgicel can be used as a modified internal matrix to prevent extrusion of the MTA into the periapical area and allow for proper MTA placement. Keywords: Apexification; Apical plug; Mineral trioxide aggregate; Calcium hydroxide; Surgicel; Modified internal matrix

scholarly journals In Vitro Assessment of Erosive Effects of Some Common Soft Drinks on Dental Hard Tissues

2019 ◽  
Vol 23 (3) ◽  
pp. 132-140
Author(s):  
Enea Bitri ◽  
Lucian Petcu ◽  
Gabriela Mocanu ◽  
Doina Paula Balaban
Keyword(s):  
Weight Loss ◽  
Titratable Acidity ◽  
Soft Drinks ◽  
Hard Tissue ◽  
Time Exposure ◽  
Prolonged Time ◽  
Dental Hard Tissue ◽  
Dental Hard Tissues ◽  
Hard Tissues ◽  
Erosive Effect

Summary Background/Aim: The chemical nature of soft drinks is acidic, so they possess the capacity to cause hard tissue erosion. The aim of this study is to assess the potentially erosive effect linked to pH and titratable acidity of some common soft drinks on dental hard tissues in prolonged time exposure. Material and Methods: Seven types of soft drinks in Romanian market were selected for this study. The pH and Titratable acidity were determined. Twenty one human dental hard tissue specimens were immersed in 5 ml solution each for 336h. Every 48h weight loss was determined for each specimen and after 336h volume changes were calculated. Enamel microhardness was determined using a Microhardness Tester model HV-1000 and compared to normal enamel microhardness. Results: The pH values of beverages ranged from 2.37 to 3.1, showing no significant differences. All specimens presented color and surface texture modifications, weight loss and volume reduction. There were found significant differences between the mean values of weight loss and enamel microhardness of each type of specimens and type of beverages tested. The most representative findings were achieved by indentations done in specific zones on Sprite® immersed specimen. This result suggest that microhardness near the eroded surface was significant lower than in other zones. Conclusions: Data obtained have shown that all the soft drinks tested had an erosive effect, causing dental hard tissue dissolution. For prolonged time exposure titratable acidity may be a major predictor for erosive potential. Dental erosion may affect different levels of enamel causing decreased enamel microhardness.

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