scholarly journals Myocardial Metabolic Abnormalities in Hypertrophic Cardiomyopathy Assessed by Iodine-123-Labeled Beta-Methyl-Branched Fatty Acid Myocardial Scintigraphy and its Relation to Exercise-Induced lschemia

1998 ◽  
Vol 62 (3) ◽  
pp. 167-172 ◽  
Author(s):  
Shinro Matsuo ◽  
Yasuyuki Nakamura ◽  
Masayuki Takahashi ◽  
Kenichi Mitsunami ◽  
Masahiko Kinoshita
Keyword(s):  
Fatty Acid ◽  
Hypertrophic Cardiomyopathy ◽  
Myocardial Scintigraphy ◽  
Metabolic Abnormalities ◽  
Iodine 123 ◽  
Exercise Induced

scholarly journals Regular consumption of cod liver oil is associated with reduced basal and exercise-induced C-reactive protein levels; a prospective observational trial

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Mette Wærstad Hansen ◽  
Stein Ørn ◽  
Christine B. Erevik ◽  
Magnus Friestad Bjørkavoll-Bergseth ◽  
Øyvind Skadberg ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Strenuous Exercise ◽  
Cod Liver Oil ◽  
Omega 3 ◽  
C Reactive Protein ◽  
Omega 3 Fatty Acid ◽  
Recreational Athletes ◽  
Reactive Protein ◽  
Supplement Use ◽  
Exercise Induced

Abstract Background Dietary supplement use among recreational athletes is common, with the intention of reducing inflammation and improving recovery. We aimed to describe the relationship between omega-3 fatty acid supplement use and inflammation induced by strenuous exercise. Methods C-reactive protein (CRP) concentrations were measured in 1002 healthy recreational athletes before and 24 h after a 91-km bicycle race. The use of omega-3 fatty acid supplements was reported in 856 out of 1002 recreational athletes, and the association between supplement use and the exercise-induced CRP response was assessed. Results Two hundred seventy-four subjects reported regular use of omega-3 fatty acid supplements. One hundred seventy-three of these used cod liver oil (CLO). Regular users of omega-3 fatty acid supplements had significantly lower basal and exercise-induced CRP levels as compared to non-users (n = 348, p < 0.001). Compared to non-users, regular users had a 27% (95% confidence interval (CI): 14–40) reduction in Ln CRP response (unadjusted model, p < 0.001) and 16% (95% CI: 5–28, p = 0.006) reduction after adjusting for age, sex, race duration, body mass index, delta creatine kinase, MET hours per week, resting heart rate and higher education. CLO was the primary driver of this response with a 34% (95% CI: 19–49) reduction (unadjusted model, p < 0.001) compared to non-users. Corresponding numbers in the adjusted model were 24% (95% CI: 11–38, p < 0.001). Conclusion Basal CRP levels were reduced, and the exercise-induced CRP response was attenuated in healthy recreational cyclists who used omega-3 fatty acid supplements regularly. This effect was only present in regular users of CLO. Trial registration NCT02166216, registered June 18, 2014 – Retrospectively registered.

Refractory exercise-induced severe mitral regurgitation in a patient with hypertrophic cardiomyopathy

2021 ◽  
Author(s):  
Masaki Ishiyama ◽  
Emiyo Sugiura ◽  
Hisato Ito ◽  
Hiroshi Nakajima ◽  
Tairo Kurita ◽  
...  
Keyword(s):  
Hypertrophic Cardiomyopathy ◽  
Mitral Regurgitation ◽  
Severe Mitral Regurgitation ◽  
Exercise Induced

Glucocorticoids produce whole body insulin resistance with changes in cardiac metabolism

2007 ◽  
Vol 292 (3) ◽  
pp. E654-E667 ◽  
Author(s):  
Dake Qi ◽  
Brian Rodrigues
Keyword(s):  
Insulin Resistance ◽  
Fatty Acid ◽  
Glucose Utilization ◽  
Experimental Studies ◽  
Cardiac Metabolism ◽  
Multiple Organ ◽  
Whole Body ◽  
Metabolic Abnormalities ◽  
Organ Systems ◽  
Per Se

Insulin resistance is viewed as an insufficiency in insulin action, with glucocorticoids being recognized to play a key role in its pathogenesis. With insulin resistance, metabolism in multiple organ systems such as skeletal muscle, liver, and adipose tissue is altered. These metabolic alterations are widely believed to be important factors in the morbidity and mortality of cardiovascular disease. More importantly, clinical and experimental studies have established that metabolic abnormalities in the heart per se also play a crucial role in the development of heart failure. Following glucocorticoids, glucose utilization is compromised in the heart. This attenuated glucose metabolism is associated with altered fatty acid supply, composition, and utilization. In the heart, elevated fatty acid use has been implicated in a number of metabolic, morphological, and mechanical changes and, more recently, in “lipotoxicity”. In the present article, we review the action of glucocorticoids, their role in insulin resistance, and their influence in modulating peripheral and cardiac metabolism and heart disease.

scholarly journals ω3 FATTY ACID ENRICHED DIET DECREASES EXERCISE INDUCED LACTACIDEMIA IN THE NEWBORN RAT.

Shock ◽  
1995 ◽  
Vol 3 ◽  
pp. 41
Author(s):  
Miroslaw S. Skalski ◽  
L. R. Farolan ◽  
M. Goto ◽  
W. P. Zeller ◽  
T. F. Myers ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Newborn Rat ◽  
Exercise Induced

Angina Pectoris Due to Severe Muscular Bridge in Hypertrophic Cardiomyopathy

1998 ◽  
Vol 6 (2) ◽  
pp. 132-134
Author(s):  
M Şah Topcuoĝlu ◽  
Ayhan Usal ◽  
Cem Kayhan ◽  
Aladdin Pekedis ◽  
Acar Tokcan ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Calcium Antagonist ◽  
Hypertrophic Cardiomyopathy ◽  
Angina Pectoris ◽  
Left Ventricular Outflow Tract ◽  
Young Patients ◽  
Ventricular Outflow Tract ◽  
Myocardial Scintigraphy ◽  
Left Ventricular ◽  
Left Ventricular Outflow

We report the case of a 39-year-old male with hypertrophic cardiomyopathy who complained of angina pectoris. The patient was treated with a beta blocker and a calcium antagonist without effect. Myocardial scintigraphy revealed anterior ischemia. Cardiac catheterization and ventriculography revealed severe systolic narrowing of the left anterior descending coronary artery and no significant pressure gradient across the left ventricular outflow tract. Myotomy was performed on a muscular bridge over the left anterior descending coronary artery and the patient's angina was relieved. In young patients with hypertrophic cardiomyopathy who develop angina refractory to medical therapy, a coexisting muscular bridge should be sought.

scholarly journals Fatty Acid Synthase as a Factor Required for Exercise-Induced Cognitive Enhancement and Dentate Gyrus Cellular Proliferation

PLoS ONE ◽  
2013 ◽  
Vol 8 (11) ◽  
pp. e77845 ◽  
Author(s):  
Nataliya E. Chorna ◽  
Iván J. Santos-Soto ◽  
Nestor M. Carballeira ◽  
Joan L. Morales ◽  
Janneliz de la Nuez ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Dentate Gyrus ◽  
Fatty Acid Synthase ◽  
Cellular Proliferation ◽  
Cognitive Enhancement ◽  
Exercise Induced
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