scholarly journals Non-invasive monitoring of brain oxygen metabolism during cardiopulmonary bypass by near-infrared spectrophotometry.

1991 ◽  
Vol 55 (4) ◽  
pp. 330-335 ◽  
Author(s):  
MASAHIDE TAMURA
Keyword(s):  
Cardiopulmonary Bypass ◽  
Near Infrared ◽  
Oxygen Metabolism ◽  
Invasive Monitoring ◽  
Infrared Spectrophotometry ◽  
Non Invasive ◽  
Brain Oxygen ◽  
Brain Oxygen Metabolism

scholarly journals Non-invasive optical neuromonitoring of the temperature-dependence of cerebral oxygen metabolism during deep hypothermic cardiopulmonary bypass in neonatal swine

2018 ◽  
Vol 40 (1) ◽  
pp. 187-203 ◽  
Author(s):  
Tiffany S Ko ◽  
Constantine D Mavroudis ◽  
Wesley B Baker ◽  
Vincent C Morano ◽  
Kobina Mensah-Brown ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Cardiopulmonary Bypass ◽  
Temperature Response ◽  
Oxygen Metabolism ◽  
Correlation Spectroscopy ◽  
Neurological Injury ◽  
Diffuse Correlation Spectroscopy ◽  
Non Invasive ◽  
Neuroprotective Strategy ◽  
Subject Variability

Management of deep hypothermic (DH) cardiopulmonary bypass (CPB), a critical neuroprotective strategy, currently relies on non-invasive temperature to guide cerebral metabolic suppression during complex cardiac surgery in neonates. Considerable inter-subject variability in temperature response and residual metabolism may contribute to the persisting risk for postoperative neurological injury. To characterize and mitigate this variability, we assess the sufficiency of conventional nasopharyngeal temperature (NPT) guidance, and in the process, validate combined non-invasive frequency-domain diffuse optical spectroscopy (FD-DOS) and diffuse correlation spectroscopy (DCS) for direct measurement of cerebral metabolic rate of oxygen ( CMRO2). During CPB, n = 8 neonatal swine underwent cooling from normothermia to 18℃, sustained DH perfusion for 40 min, and then rewarming to simulate cardiac surgery. Continuous non-invasive and invasive measurements of intracranial temperature (ICT) and CMRO2 were acquired. Significant hysteresis ( p < 0.001) between cooling and rewarming periods in the NPT versus ICT and NPT versus CMRO2 relationships were found. Resolution of this hysteresis in the ICT versus CMRO2 relationship identified a crucial insufficiency of conventional NPT guidance. Non-invasive CMRO2 temperature coefficients with respect to NPT ( Q10 = 2.0) and ICT ( Q10 = 2.5) are consistent with previous reports and provide further validation of FD-DOS/DCS CMRO2 monitoring during DH CPB to optimize management.

Relation between brain oxygen metabolism and temperature gradient between brain and bladder

2003 ◽  
pp. 251-253 ◽  
Author(s):  
Atsushi Sakurai ◽  
K. Kinoshita ◽  
T. Atsumi ◽  
T. Moriya ◽  
A. Utagawa ◽  
...  
Keyword(s):  
Temperature Gradient ◽  
Oxygen Metabolism ◽  
Brain Oxygen ◽  
Brain Oxygen Metabolism

scholarly journals Non-invasive monitoring of chronic liver disease via near-infrared and shortwave-infrared imaging of endogenous lipofuscin

2020 ◽  
Vol 4 (8) ◽  
pp. 801-813 ◽  
Author(s):  
Mari Saif ◽  
Wilhelmus J. Kwanten ◽  
Jessica A. Carr ◽  
Ivy X. Chen ◽  
Jessica M. Posada ◽  
...  
Keyword(s):  
Liver Disease ◽  
Chronic Liver Disease ◽  
Near Infrared ◽  
Infrared Imaging ◽  
Chronic Liver ◽  
Invasive Monitoring ◽  
Non Invasive ◽  
Shortwave Infrared
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