scholarly journals Effects of L-carnitine on ventricular arrhythmias after coronary reperfusion.

1983 ◽  
Vol 47 (5) ◽  
pp. 536-542 ◽  
Author(s):  
AKIRA KOBAYASHI ◽  
YOSHIKAZU SUZUKI ◽  
TADASHI KAMIKAWA ◽  
HIDEHARU HAYASHI ◽  
YOSHINORI MASUMURA ◽  
...  
1993 ◽  
Vol 71 (2) ◽  
pp. 103-111 ◽  
Author(s):  
B. G. Benfey

The myocardium of animals and man possesses α1-adrenoceptors in addition to β-adrenoceptors. Ischemia increases sympathetic tone, and ventricular arrhythmias can occur by β- and α1-adrenoceptor stimulation. I believe that α1-adrenoceptor blocking drugs have antifibrillatory effects and will review the data that support this condition. The effect of α1,-adrenoceptor blocking drugs on the incidence of ventricular fibrillation in acute coronary artery occlusion and (or) reperfusion has been determined in 24 studies in conscious and anesthetized dogs and rats, anesthetized cats and pigs, and rat and guinea-pig isolated hearts. The drugs reduced the incidence of fibrillation from 35 to 24% in coronary occlusion and from 61 to 29% in reperfusion.Key words: heart, coronary occlusion, coronary reperfusion, ventricular fibrillation, α1-adrenoceptor blocking drugs.


1985 ◽  
Vol 18 (1) ◽  
pp. 87-96 ◽  
Author(s):  
Glenn Kabell ◽  
Benjamin J. Scherlag ◽  
Johannes Brachmann ◽  
Lura Harrison ◽  
Ralph Lazzara

2007 ◽  
Vol 6 (1) ◽  
pp. 155-156
Author(s):  
J MARQUES ◽  
A KANSKY ◽  
I MENDOZA ◽  
L LOPEZGOMEZ ◽  
F MOLEIRO ◽  
...  

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