scholarly journals Plasma Norepinephrine Levels and Hemodynamics in Young Patients with Essential Hypertension : VII CONFERENCE ON THE PATHOGENESIS OF HYPERTENSION

1978 ◽  
Vol 42 (5) ◽  
pp. 609-612 ◽  
Author(s):  
YUKIO MIURA ◽  
KIYOSHI KOBAYASHI ◽  
HISAICHI SAKUMA ◽  
HIROSHI TOMIOKA ◽  
MAKI ADACHI ◽  
...  
Hypertension ◽  
1984 ◽  
Vol 6 (3) ◽  
pp. 315-321 ◽  
Author(s):  
K Masuo ◽  
T Ogihara ◽  
Y Kumahara ◽  
A Yamatodani ◽  
H Wada

2013 ◽  
Vol 5 (01) ◽  
pp. 26-29 ◽  
Author(s):  
Abiodun Mathias Emokpae ◽  
Aliyu Abdu ◽  
Humphrey Benedo Osadolor

ABSTRACT Background: High blood pressure (BP) is a major health problem in Nigeria and the involvement of thyroid hormones in this condition has not been evaluated in this center. Objective: The objective of this study was to evaluate the proportion of patients with an essential hypertension who had abnormal thyroid hormone levels and the type of thyroid disorders commonly observed in this group of patients. Materials and Methods: A retrospective study of 94 patients (30 males, aged 30.4 ± 2 years and 64 females, aged 43.4 ± 1.3 years) with essential hypertension was carried out between January 2005 and December 2007. Demographic and other medical information were obtained from the health records. Analysis of laboratory results of triiodothyronine (T3), Thyroxine (T4), and thyroid stimulating hormone (TSH) were made. Results: Of the 94 patients evaluated, 26 (27.7%) had abnormal thyroid hormone levels, with 23.4% having hyperthyroidism, 4.3% had sub-clinical hypothyroidism and none had overt hypothyroidism. Of the 26 subjects with abnormal thyroid hormone levels, 18 (69.2%) were females while 8 (30.8%) were males. Out of the 18 female subjects with abnormal thyroid hormone levels, 16 had hyperthyroid levels while 2 had sub-clinical hypothyroid levels. Out of the 8 male patients, 6 had hyperthyroid hormone levels while 2 had sub-clinical hypothyroid levels. Conclusion: Thyroid hormone abnormalities are common in patients with essential hypertension. Hyperthyroidism was the most common thyroid disorder observed. Young patients presenting with essential hypertension should be screened for thyroid hormone abnormalities since they can best be managed by treating the underlying causes.


Neuropeptides ◽  
1995 ◽  
Vol 29 (2) ◽  
pp. 97-101 ◽  
Author(s):  
V Sánchez-Margalet ◽  
M Valle ◽  
J.A Lobón ◽  
F Escobar-Jiménez ◽  
R Pérez-Cano ◽  
...  

1988 ◽  
Vol 6 (4) ◽  
pp. S381-383 ◽  
Author(s):  
Karin S. Kraft ◽  
Michael Behrendt ◽  
Rainer Kolloch ◽  
Klaus-Otto Stumpe

2020 ◽  
Vol 43 (6) ◽  
pp. 511-517 ◽  
Author(s):  
Hong-Gang Zhang ◽  
Qiu-Ju Zhang ◽  
Bing-Wei Li ◽  
Lu-Han Li ◽  
Xiao-Hong Song ◽  
...  

1989 ◽  
Vol 118 (4) ◽  
pp. 775-781 ◽  
Author(s):  
Sverre E. Kjeldsen ◽  
Nicholas J. Schork ◽  
Paul Leren ◽  
Ivar K. Eide

1978 ◽  
Vol 55 (s4) ◽  
pp. 69s-71s ◽  
Author(s):  
Y. Miura ◽  
K. Kobayashi ◽  
H. Sakuma ◽  
H. Tomioka ◽  
M. Adachi ◽  
...  

1. Plasma noradrenaline concentrations and haemodynamic status were simultaneously studied in young patients with uncomplicated essential hypertension and in age-matched normal controls. 2. Resting plasma noradrenaline in the controls tended to increase slightly, but progressively, with age. The hypertensive subjects had significantly higher plasma noradrenaline concentrations than those in the controls, but these values did not show any age-related variation. The response of plasma noradrenaline to the standing position tended to increase with age in the controls, whereas plasma noradrenaline in the hypertensive subjects showed a wide range of responses without any fixed relationship with age. 3. The cardiac index was significantly greater in the labile hypertensive subjects than in the controls, whereas total peripheral resistance was significantly greater in the sustained hypertensive subjects than in the labile patients and in the controls. Mean arterial pressure in these patients was closely related with the values of total peripheral resistance rather than with the cardiac index. 4. Of the patients with raised plasma noradrenaline 80% showed significantly increased values of either total peripheral resistance or cardiac index. Plasma noradrenaline was correlated significantly to total peripheral resistance, and marginally to mean arterial pressure. 5. These findings support the view that sympathetic nervous overactivity is an important factor underlying the haemodynamic findings in these patients.


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