scholarly journals Relationship of Admission QRS Duration and Changes in QRS Duration With Myocardial Reperfusion in Patients With Acute ST Segment Elevation Myocardial Infarction (STEMI) Treated With Fibrinolytic Therapy

2008 ◽  
Vol 72 (6) ◽  
pp. 873-879 ◽  
Author(s):  
Fehmi Kacmaz ◽  
Orhan Maden ◽  
Savas Aksuyek ◽  
Cagin Ureyen ◽  
Ömer Alyan ◽  
...  
Author(s):  
Pedro Engel Gonzalez ◽  
Wally Omar ◽  
Kunal V. Patel ◽  
James A. de Lemos ◽  
Anthony A. Bavry ◽  
...  

The ongoing coronavirus disease 2019 pandemic has resulted in additional challenges for systems designed to perform expeditious primary percutaneous coronary intervention for patients presenting with ST-segment–elevation myocardial infarction. There are 2 important considerations: the guideline-recommended time goals were difficult to achieve for many patients in high-income countries even before the pandemic, and there is a steep increase in mortality when primary percutaneous coronary intervention cannot be delivered in a timely fashion. Although the use of fibrinolytic therapy has progressively decreased over the last several decades in high-income countries, in circumstances when delays in timely delivery of primary percutaneous coronary intervention are expected, a modern fibrinolytic-based pharmacoinvasive strategy may need to be considered. The purpose of this review is to systematically discuss the contemporary role of an evidence-based fibrinolytic reperfusion strategy as part of a pharmacoinvasive approach, in the context of the emerging coronavirus disease 2019 pandemic.


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