scholarly journals Patients After Atrial Switch Operation for Transposition of the Great Arteries Can Not Increase Stroke Volume Under Dobutamine Stress as Opposed to Patients With Congenitally Corrected Transposition

2008 ◽  
Vol 72 (7) ◽  
pp. 1130-1135 ◽  
Author(s):  
Sohrab Fratz ◽  
Alfred Hager ◽  
Raymonde Busch ◽  
Harald Kaemmerer ◽  
Markus Schwaiger ◽  
...  
2021 ◽  
pp. 1-11
Author(s):  
Corinna Lebherz ◽  
Martin Gerhardus ◽  
Astrid Elisabeth Lammers ◽  
Paul Helm ◽  
Oktay Tutarel ◽  
...  

Abstract Background: Adults with systemic right ventricle have a significant risk for long-term complications such as arrhythmias or heart failure. Methods: A nationwide retrospective study based on the German National Register for Congenital Heart Disease was performed. Patients with transposition of the great arteries after atrial switch operation or congenitally corrected TGA were included. Results: Two hundred and eight-five patients with transposition of the great arteries after atrial switch operation and 95 patients with congenitally corrected transposition of the great arteries were included (mean age 33 years). Systolic function of the systemic ventricle was moderately or severely reduced in 25.5 % after atrial switch operation and in 35.1% in patients with congenitally corrected transposition. Regurgitation of the systemic atrioventricular valve was present in 39.5% and 43.2% of the cases, respectively. A significant percentage of patients also had a history for supraventricular or ventricular arrhythmias. However, polypharmacy of cardiovascular drugs was rare (4.5%) and 38.5 % of the patients did not take any cardiovascular medication. The amount of cardiovascular drugs taken was associated with NYHA class as well as systemic right ventricular dysfunction. Patients with congenitally corrected transposition were more likely to receive pharmacological treatment than patients after atrial switch operation. Conclusion: A significant portion of patients with systemic right ventricle suffer from a relevant systemic ventricular dysfunction, systemic atrioventricular valve regurgitation, and arrhythmias. Despite this, medication for heart failure treatment is not universally used in this cohort. This emphasises the need for randomised trials in patient with systemic right ventricle.


2016 ◽  
Vol 27 (3) ◽  
pp. 600-604
Author(s):  
Rodrigo Rios ◽  
Susan R. Foerster ◽  
Todd M. Gudausky

AbstractThe Melody® transcatheter pulmonary valve system was developed for placement within right ventricle-to-pulmonary artery conduits in patients with CHD for treatment of stenosis or regurgitation, providing an alternative to open-heart surgery. Abnormal systemic venous connections altering the catheter course to the right ventricle-to-pulmonary artery conduit may present a challenge to Melody® valve implantation. We present two such cases, in which the Melody® valve was successfully implanted in teenage patients with congenitally corrected transposition of the great arteries after Senning atrial switch operation. Despite the abnormal catheter course, the right ventricle-to-pulmonary artery was approachable via the right femoral vein allowing for deployment of the Melody® valve in the appropriate position. This suggests that systemic vein-to-left atrium baffles are not prohibitive of Melody® valve implantation. This is an important implication considering the substantial population of ageing patients with CHD who have undergone atrial switch. Melody® valve implantation can be considered as a viable option for treatment of these patients if they develop right ventricle-to-pulmonary artery conduit failure.


2005 ◽  
Vol 13 (3) ◽  
pp. 208-210 ◽  
Author(s):  
Thaworn Subtaweesin ◽  
Somchai Sriyoschati

The atrial switch operation with the Rastelli procedure is becoming popular for treatment of the subgroup of corrected transposition of the great arteries with ventricular septal defect and pulmonary obstruction. This technique eliminates the problem of short- and long-term right ventricular failure, and decreases the incidence of iatrogenic atrioventricular heart block. Between April 2001 and November 2002, this technique was used in 3 patients aged 5 to 7 years. Two had a Senning operation and one had a Mustard operation. There was no operative death. The first patient needed re-operation to close the sternum. The last patient was re-explored for bleeding. All patients were in New York Heart Association functional class I at their last follow-up. The atrial switch plus Rastelli procedure is feasible in this subgroup of corrected transposition, but longer follow-up is necessary to determine whether this approach is indeed warranted.


2015 ◽  
Vol 65 (10) ◽  
pp. A497
Author(s):  
Carolyn Wilhelm ◽  
Tracey Sisk ◽  
Sharon Roble ◽  
Joanne Chisolm ◽  
John Cheatham ◽  
...  

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