scholarly journals Positive Pressure Ventilation Treatment Reduces Plasma Levels of Amino Terminal-Pro Brain Natriuretic Peptide in Congestive Heart Failure Patients With Sleep Apnea

2006 ◽  
Vol 70 (5) ◽  
pp. 572-574 ◽  
Author(s):  
Zhi-Hui Zhao ◽  
Zhi-Hong Liu ◽  
Qin Luo ◽  
Chang-Ming Xiong ◽  
Xin-Hai Ni ◽  
...  
1998 ◽  
Vol 94 (2) ◽  
pp. 135-139 ◽  
Author(s):  
Yuji Yoshitomi ◽  
Toshio Nishikimi ◽  
Shunichi Kojima ◽  
Morio Kuramochi ◽  
Shuichi Takishita ◽  
...  

1. Adrenomedullin, a newly identified vasorelaxant peptide, participates in the regulation of the cardiovascular system. To investigate the pathophysiological significance of adrenomedullin in patients with acute myocardial infarction, we measured plasma levels of adrenomedullin. 2. Cardiac catheterization was performed on admission, after 1 day, and after 4 weeks in 36 patients with acute myocardial infarction. We measured plasma levels of adrenomedullin, atrial natriuretic peptide and brain natriuretic peptide in the right atrium, pulmonary artery and aorta. 3. Plasma levels of adrenomedullin in the right atrium (mean ± SEM) were significantly increased on admission (4.2 ± 2.6 h) in patients with acute myocardial infarction (10.6 ± 1.0 pmol/l) compared with controls (5.2 ± 0.3 pmol/l, P < 0.01). In addition, plasma levels of adrenomedullin were further elevated in patients with congestive heart failure (12.3 ± 1.4 pmol/l) compared with patients without congestive heart failure (7.8 ± 0.6 pmol/l, P < 0.01). In patients with congestive heart failure, plasma adrenomedullin on admission significantly correlated with atrial natriuretic peptide and brain natriuretic peptide. 4. These results suggest that plasma adrenomedullin increases in the early phase of acute myocardial infarction and that volume expansion may be one of the additional stimuli for the release of adrenomedullin in patients with acute myocardial infarction complicated by congestive heart failure.


2006 ◽  
Vol 47 (1) ◽  
pp. 91-97 ◽  
Author(s):  
Saif Anwaruddin ◽  
Donald M. Lloyd-Jones ◽  
Aaron Baggish ◽  
Annabel Chen ◽  
Daniel Krauser ◽  
...  

2021 ◽  
pp. 45-46
Author(s):  
Shahrukh Khilji ◽  
Bushra Fiza ◽  
Shehreen Akhtar ◽  
Jai Prakash ◽  
Maheep Sinha

INTRODUCTION: Congestive Heart Failure is a complex physiological syndrome caused from structural or functional alterations to the myocardium. Lactate is produced by anaerobic metabolism and is secreted by the Brain-Natriuretic peptide heart ventricles in response to left ventricular stretching or wall tension. AIM: The aim of the study was to evaluate Brain-Natriuretic Peptide, Lactate levels and Blood pressure in Congestive Heart Failure patients and compared them with healthy individual. MATERIALS AND METHODS: Total 80 participants who fullled the inclusion and exclusion criteria were enrolled in the study. They were divided into two group i.e., case and control group. Case group included 40 patients of Congestive Heart Failure, age between 18-65 years and control group comprised of 40 healthy individuals with similar age range. Blood sample were drawn and analyzed for the evaluation of Serum lactate and Brain-Natriuretic Peptide. Blood Pressure was also measured in both the groups. RESULT: The present study has demonstrated that the level of Brain-Natriuretic Peptide and lactate were signicantly high in Congestive heart failure patients when compared with control group. Systolic and Diastolic blood pressure were also higher among patients group. CONCLUSION: The results of the study suggested that the levels of Lactate and Brain-Natriuretic Peptide were high in Congestive heart failure patients when compared with healthy individual. Systolic and Diastolic blood pressure were also higher among patients group. Elevated lactate and Brain-Natriuretic Peptide level can be recommended as useful indicator of poor prognosis and hence can be helpful in early identication of patients at risk.


CHEST Journal ◽  
2005 ◽  
Vol 127 (5) ◽  
pp. 1667-1673 ◽  
Author(s):  
Carmen Carmona-Bernal ◽  
Esther Quintana-Gallego ◽  
Manuel Villa-Gil ◽  
Angeles Sánchez-Armengol ◽  
Angel Martínez-Martínez ◽  
...  

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