scholarly journals Carotid Atherosclerosis as a Risk Factor for Complex Aortic Lesions in Patients With Ischemic Cerebrovascular Disease

2003 ◽  
Vol 67 (7) ◽  
pp. 597-600 ◽  
Author(s):  
Yoshiomi Shimizu ◽  
Kazuo Kitagawa ◽  
Yoji Nagai ◽  
Masako Narita ◽  
Hidetaka Hougaku ◽  
...  
Keyword(s):  
Risk Factor ◽  
Cerebrovascular Disease ◽  
Carotid Atherosclerosis ◽  
Ischemic Cerebrovascular Disease ◽  
Aortic Lesions

scholarly journals Apolipoprotein e gene polymorphism as a risk factor for ischemic cerebrovascular disease

2004 ◽  
Vol 23 (3) ◽  
pp. 255-264 ◽  
Author(s):  
Sanja Stankovic ◽  
Zagorka Jovanovic-Markovic ◽  
Nada Majkic-Singh ◽  
Aleksandra Stankovic ◽  
Sanja Glisic ◽  
...  
Keyword(s):  
Risk Factor ◽  
Gene Polymorphism ◽  
Cerebrovascular Disease ◽  
Apolipoprotein E ◽  
Apoe Genotype ◽  
Control Group ◽  
Ischemic Cerebrovascular Disease ◽  
Genotype Frequencies ◽  
Significant Difference ◽  
E4 Allele

The possible association of apolipoprotein E (apoE) DNA polymorphism with ischemic cerebrovascular disease was evaluated in 65 patients who had suffered completed stroke or transient ischemic attack and 330 healthy controls. ApoE genotypes were determined by restriction isotyping/MADGE analysis. Significant difference in apoE genotype frequencies between case and control group was observed (p<0.01). Patients affected by ischemic stroke had higher frequency of E4 allele and lower E2 allele than age-matched control subjects. Compared with persons without E4 allele, carriers of an E4 allele had 2.1 times higher risk of incident stroke. Our results indicate that the apoE gene polymorphism may be a risk factor for the development of ischemic cerebrovascular disease in Serbian population..

scholarly journals Association of Vegetable Nitrate Intake With Carotid Atherosclerosis and Ischemic Cerebrovascular Disease in Older Women

Stroke ◽  
2017 ◽  
Vol 48 (7) ◽  
pp. 1724-1729 ◽  
Author(s):  
Catherine P. Bondonno ◽  
Lauren C. Blekkenhorst ◽  
Richard L. Prince ◽  
Kerry L. Ivey ◽  
Joshua R. Lewis ◽  
...  
Keyword(s):  
Cerebrovascular Disease ◽  
Older Women ◽  
Carotid Atherosclerosis ◽  
Ischemic Cerebrovascular Disease ◽  
Nitrate Intake

APOE genotype as a risk factor for ischemic cerebrovascular disease: A meta-analysis

Neurology ◽  
1999 ◽  
Vol 53 (6) ◽  
pp. 1308-1308 ◽  
Author(s):  
M. O. McCarron ◽  
D. Delong ◽  
M. J. Alberts
Keyword(s):  
Risk Factor ◽  
Cerebrovascular Disease ◽  
Meta Analysis ◽  
Apoe Genotype ◽  
Ischemic Cerebrovascular Disease

Abstract 11: Compliance With Risk Factor Optimization and Medical Therapy in Patients With Peripheral Vascular Disease (Peripheral Artery and Ischemic Cerebrovascular Disease) Compared to Ischemic Heart Disease.

2015 ◽  
Vol 8 (suppl_2) ◽  
Author(s):  
Ravi S Hira ◽  
Yashashwi Pokharel ◽  
Jennifer Cowart ◽  
Julia M Akeroyd ◽  
David Ramsey ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Risk Factor ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Cerebrovascular Disease ◽  
Medical Therapy ◽  
Hypertension Control ◽  
Peripheral Artery ◽  
Ischemic Cerebrovascular Disease ◽  
Statin Use

Background: Cardiovascular disease (CVD) is a systemic process with patients developing atherosclerosis in multiple vascular beds including ischemic heart disease (IHD), ischemic cerebrovascular disease (ICVD) and peripheral artery disease (PAD). PAD and ICVD are associated with increased risk of subsequent myocardial infarction, stroke and death. Medical management and risk factor optimization are recommended for all patients with CVD. Compliance with measures in patients with ICVD and PAD compared to IHD is not known. Methods: In a large national cohort, we identified 1,242,015 patients with cardiovascular disease (CVD) receiving care in 130 Veterans Affairs facilities between 10/1/2013 and 9/30/2014. CVD was defined as the presence of IHD, PAD, or ICVD. We assessed the frequency of compliance with performance measures in patients with IHD (with or without concomitant PAD or ICVD), PAD only, ICVD only, and PAD+ICVD groups. We compared compliance with hypertension control (BP <140/90 mmHg), diabetes control (HbA1C<7.0% among diabetics), and the use of statin therapy between IHD and PAD, ICVD, or PAD+ICVD groups. A composite of all 3 measures (BP control, statin use, HbA1C <7% among diabetics) termed optimal medical therapy (OMT) was also compared between groups. Multivariate logistic regression was performed with IHD group as the referent category. Results (Table): IHD patients comprised 989,380 (79.7%), PAD only 70,404 (5.7%), ICVD only 163,730 (13.2%) and PAD + ICVD 18,501 (1.5%) of the cohort. Compliance with most measures (hypertension control, statin use) as well as OMT was lower for PAD or ICVD patients compared with IHD patients with minimal differences between IHD and PAD +CVD group. Overall, only 32.3%-41.8% received OMT (i.e. met the composite measure). Conclusions: Compliance with OMT was low in all patients. Patients with PAD or ICVD were less likely to receive OMT compared with IHD. Our results suggest potential for improvement in OMT for all CVD patients especially those with PAD and ICVD.

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