scholarly journals Modification of Treatment Strategies Over a Period of 14 Years Has Markedly Reduced Cardiac Events Among Post-Myocardial Infarction Patients

2002 ◽  
Vol 66 (10) ◽  
pp. 881-885 ◽  
Author(s):  
Kinji Ishikawa ◽  
Akio Kimura ◽  
Takaaki Taniwa ◽  
Toshihiko Takenaka ◽  
Takahiro Hayashi ◽  
...  
2000 ◽  
Vol 41 (3) ◽  
pp. 279-294 ◽  
Author(s):  
Ishikawa Kinji ◽  
Miyataka Masaru ◽  
Kanamasa Ken ◽  
Hayashi Takahiro ◽  
Takenaka Toshihiko ◽  
...  

2007 ◽  
Vol 190 (6) ◽  
pp. 460-466 ◽  
Author(s):  
Joost P. van Melle ◽  
Peter de Jonge ◽  
Adriaan Honig ◽  
Aart H. Schene ◽  
Astrid M. G. Kuyper ◽  
...  

BackgroundDepression following myocardial infarction is associated with poor cardiac prognosis. It is unclear whether antidepressant treatment improves long-term depression status and cardiac prognosis.AimsTo evaluate the effects of antidepressant treatment compared with usual care in an effectiveness study.MethodIn a multicentre randomised controlled trial, 2177 myocardial infarction patients were evaluated for ICD–10 depression and randomised to intervention (n=209) or care as usual (n=122). Both arms were evaluated at 18 months post-myocardial infarction for long-term depression status and new cardiac events.ResultsNo differences were observed between intervention and control groups in mean scores on the Beck Depression Inventory (11.0, s.d.=7.5 v. 10.2, s.d.=5.l, P=0.45) or presence of ICD-10 depression (30.5 v. 32.1%, P=0.68). The cardiac event rate was 14% among the intervention group and 13% among controls (OR=1.07, 95% CI 0.57-2.00).ConclusionsAntidepressant treatment did not alter long-term depression post-myocardial infarction status or improve cardiac prognosis.


2010 ◽  
Vol 72 (6) ◽  
pp. 563-569 ◽  
Author(s):  
Annelieke M. Roest ◽  
Elisabeth J. Martens ◽  
Johan Denollet ◽  
Peter de Jonge

2000 ◽  
Vol 64 (5) ◽  
pp. 358-364 ◽  
Author(s):  
Kinji Ishikawa ◽  
Masaru Miyataka ◽  
Ken Kanamasa ◽  
Takahiro Hayashi ◽  
Toshihiko Takenaka ◽  
...  

Angiology ◽  
2021 ◽  
pp. 000331972110125
Author(s):  
Yong Hoon Kim ◽  
Ae-Young Her ◽  
Myung Ho Jeong ◽  
Byeong-Keuk Kim ◽  
Sung-Jin Hong ◽  
...  

The 2-year clinical outcomes according to pre-percutaneous coronary intervention (PCI) thrombolysis in myocardial infarction (TIMI) flow grade and reperfusion timing were investigated in patients with non-ST-segment elevation myocardial infarction (NSTEMI) who received newer-generation drug-eluting stents. A total of 7506 NSTEMI patients were divided into 2 groups: early (PCI ≤ 24 hours: n = 6398; pre-PCI TIMI 0/1 [n = 2729], pre-PCI TIMI 2/3 [n = 3669]) and delayed (PCI > 24 hours: n = 1108; pre-PCI TIMI 0/1 [n = 428], pre-PCI TIMI 2/3 [n = 680]) invasive groups. Major adverse cardiac events were defined as all-cause death, recurrent myocardial infarction, or any repeat revascularization. All-cause death ( P = 0.005 and 0.009, respectively) and cardiac death ( P = .003 and 0.046, respectively) were significantly higher in pre-PCI TIMI 0/1 patients than in pre-PCI TIMI 2/3 patients both in the early and delayed invasive groups. In pre-PCI TIMI 0/1 patients, all-cause death rate was significantly higher in the delayed group ( P = .023). In pre-PCI TIMI 2/3 patients, the clinical end point was similar between the 2 groups. An early invasive strategy is preferred to a delayed invasive strategy in reducing all-cause death in patients with pre-PCI TIMI 0/1. However, in patients with pre-PCI TIMI 2/3, both treatment strategies are acceptable.


2016 ◽  
Vol 9 (1) ◽  
pp. 217
Author(s):  
Hala Soomro ◽  
Salik Aleem ◽  
Mujtaba Hussain ◽  
Ali Alam ◽  
Ali Qadeer ◽  
...  

BACKGROUND: Aspirin non-adherence or discontinuation is associated with an almost three-fold increase in risk of major adverse cardiac events. Compliance, commonly known as adherence, has been a major health care issue. Some studies have reported non-adherence rates to aspirin as high as fifty percent. The main objective of this study was to determine the frequency and predictors of non-compliance to aspirin in post myocardial infarction patients.METHODS: This cross sectional study was conducted over a period of 3 months from May 2015 to July 2015 at Civil Hospital, Karachi. All patients visiting Cardiology out-patient department (OPD) with previously diagnosed myocardial infarction were included in the study. Patients who were not prescribed aspirin or those with contraindication to aspirin therapy such as hemophiliacs and peptic ulcer disease patients, and those with memory problems were excluded from the study. A pre-coded questionnaire was presented to the selected sample of 456 patients. Compliance was assessed through self-report. Chi square test was used as the primary statistical test.RESULTS: Out of 456 patients, 39% (n=178) were non-compliant to aspirin therapy. The most common reported cause for non-compliance was the failure to remember taking the drug reported by 40.7% (n=72) of the people. The second most common cause was the lack of awareness of the importance of the drug and the possible side effects of not taking it 31.4% (n =56).CONCLUSION: It can be concluded that non-compliance to aspirin is a major problem present in Pakistan. With the number of cardiovascular deaths increasing around the globe and in Pakistan, it is vital that non-compliance to aspirin should be taken as a serious issue.


Sign in / Sign up

Export Citation Format

Share Document