The Influence of Infra-red Rays upon the Circulatory System of Human Body : The Sixth Report. The Change of Electrocardiogram in Cases of Myocardiac Weakness

Objective: China and many developing countries has placed high expectations on the general practice healthcare system in terms of lowering medical costs and improving the health status of the multimorbid population in recent years. However, the prevalence of multimorbidity among inpatients attending the general practice department of hospitals and its policy implications are largely unknown. The current study aimed to analyze the prevalence of comorbidities among inpatients attending the general practice department of the tertiary Grade-A Hospitals in China, and put forward evidence-based policy recommendations.Methods: Between December 2016 and November 2020, 351 registered general practitioners from 27 tertiary hospitals were selected, and their direct admissions were evaluated. The rate and composition ratio were used for descriptive analysis of the clinical and epidemiological characteristics of multimorbidity. A backward stepwise algorithm was used to explore independent variables. The absence of multicollinearity and plausible interactions among variables were tested to ensure the robustness of the logistic regression model. The pyramid diagram was used to show the link between gender and the involved human body system in multimorbidity.Results: Multimorbidity was present in 93.1% of the 64, 395 patients who were admitted directly. Multimorbidity was significantly more prevalent in patients aged 45–59 years (OR=3.018, 95% CI=1.945–4.683), 60–74 years (OR = 4.349, 95% CI = 2.574–7.349), ≥75 years (OR = 7.804, 95% CI = 3.665–16.616), and those with body mass index (BMI) ≥ 28 kg/m2 (OR = 3.770, 95% CI = 1.453–9.785). The circulatory system was found to be the most commonly involved human body system in multimorbidity, accounting for 79.2% (95% CI = 78.8–79.5%) of all cases. Significant gender inequity was further observed in the involved human body system in multimorbidity.Conclusion: Multimorbidity is likely common among the inpatients attending the general practice department of hospitals in China and many developing countries, with significant gender inequity in the involved human body systems. Effective countermeasures include establishing a GP-PCIC multimorbidity prevention and control model and enhancing the multimorbidity of elderly and obese patients at both the clinical and healthy lifestyle levels. The diagnosis and treatment capabilities of GPs on the circulatory, endocrine, metabolic, digestive, and respiratory systems should be prioritized.

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Embryonic development—the first few weeks

Anatomy for Dental Students ◽

10.1093/oso/9780199234462.003.0014 ◽

2013 ◽

Author(s):

Martin E. Atkinson

Keyword(s):

Embryonic Development ◽

Human Body ◽

Circulatory System ◽

Building Blocks ◽

The Body ◽

The Other ◽

Developmental Anatomy ◽

Fetal Period ◽

Embryonic Period ◽

Degree Of Overlap

Embryology is a fascinating subject and is the foundation of the development, growth, and maturation of all the cells, organs, and tissues of the body. Strictly, embryology is the study of the early processes of development beginning at fertilization and following the processes that turn a single cell into a multicellular organism. It is all about generation of the building blocks required to make a human body. Developmental anatomy is the study of how these building blocks are turned into specific cells, tissues, and organs as well as the general growth of the body. As you will soon appreciate in the following paragraphs, all organs and systems do not develop at the same rate so there is a degree of overlap between embryology and developmental anatomy. For example, the heart and circulatory system must develop and be functioning very early in development to ensure adequate supplies of nutrients to the developing fetal tissues. Teeth, on the other hand, are not going to be used until about six months after birth at the earliest; while the heart is already beating away, each developing tooth is merely a tiny group of cells bearing little resemblance to a fully formed tooth. Human gestation is considered to take nine months; more accurately, it usually lasts for 38 to 39 weeks from fertilization to birth. Clinically, it is divided into three trimesters of three months each. In this chapter, we will focus on events in the first few weeks. During the first two and a half weeks after fertilization, the very basic building blocks are formed from the single fertilized cell; this is the pre-embryonic period. The embryonic period covers the next five and half weeks during which these basic building blocks develop into the cells, tissues, and organs. As already indicated, some of these may be in a very rudimentary state at the end of the embryonic period. The remaining 30 or so weeks is the fetal period when the tissues and organs of the body grow and develop and the fetus grows considerably. We are not fully mature organisms at birth and have another 20 years a-growing.

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Body-on-a chip: Using microfluidic systems to predict human responses to drugs

Pure and Applied Chemistry ◽

10.1351/pac-con-09-10-44 ◽

2010 ◽

Vol 82 (8) ◽

pp. 1635-1645 ◽

Cited By ~ 18

Author(s):

Michael L. Shuler ◽

Mandy B. Esch

Keyword(s):

Cell Culture ◽

Human Body ◽

Mammalian Cells ◽

Circulatory System ◽

Systemic Circulation ◽

Multidrug Resistant ◽

Toxicological Studies ◽

In Vitro Systems ◽

Barrier Tissues

Using an in vitro platform technology that combines microfabricated devices with cell culture, we seek to understand the response of the human body to pharmaceuticals and combinations of pharmaceuticals. Computer models of the human body guide the design of in vitro systems we call micro cell culture analogs (μCCAs) or “body-on-a-chip” devices. A μCCA device is a physical representation of a physiologically based pharmacokinetic (PBPK) model and contains mammalian cells cultured in interconnected microchambers to represent key organs linked through a circulatory system. μCCAs can provide inexpensive means for realistic, accurate, and rapid-throughput toxicological studies that do not require experimenting with animals and reveal toxic effects that can result from interactions between organs. As the natural length scale in biological systems is on the order of 10–100 μm, operating on the microscale allows us to mimic physiological relationships more accurately. We summarize proof-of-concept experiments using mixtures of drugs to treat multidrug-resistant (MDR) cancer and colon cancer. We discuss the extension of the μCCA concept to systems that connect barrier tissues with systemic circulation. Examples with models of the gastro-intestinal (GI) tract are provided.

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EXAMINING SECONDARY SCHOOL STUDENTS’ MISCONCEPTIONS ABOUT THE HUMAN BODY: CORRELATIONS BETWEEN THE METHODS OF DRAWING AND OPEN-ENDED QUESTIONS

Journal of Baltic Science Education ◽

10.33225/jbse/19.18.549 ◽

2019 ◽

Vol 18 (4) ◽

pp. 549-557 ◽

Cited By ~ 1

Author(s):

Jana Fančovičová ◽

Pavol Prokop

Keyword(s):

Secondary School ◽

Human Body ◽

Age Groups ◽

Circulatory System ◽

Cross Cultural ◽

Complete Understanding ◽

School Students ◽

Cultural Research ◽

Cross Cultural Research ◽

Scientific Phenomena

Students of various age groups manifest numerous explanations that differ from what is known to be scientifically correct. Misconceptions about the human body are one of the best studied areas of students’ understanding of scientific phenomena. To explore misconceptions, researchers have at their disposal various methods which can lead to different results. In order to find an effective, cheap and representative diagnostic instrument, correlations between scores obtained by open-ended questions and drawings on the example of the human circulatory system were examined. Open-ended questions provide a more complete understanding of student learning but are harder to evaluate objectively in comparison with drawings, particularly in cross-cultural research. Correlations among scores obtained by these two methods in the present research were moderate, which suggests that drawings reflect students’ understanding of the circulatory system, albeit not perfectly. Although drawings probably never provide a complete understanding of children’s ideas about science, this cheap and time effective method is recommended particularly in cross-cultural research, where standard, comparable conditions are hard to achieve. Keywords: circulatory system, human heart, human body, students’ ideas.

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