scholarly journals Developmental Toxicity of Bisphenol-A on Post-Implantation Rat Embryos Cultured in Vitro

2010 ◽  
Vol 56 (1) ◽  
pp. 57-64 ◽  
Author(s):  
Dong Li ◽  
Hua Fan ◽  
Wen-Jing Ye ◽  
Hai-Feng Hou
Development ◽  
1976 ◽  
Vol 36 (1) ◽  
pp. 133-144
Author(s):  
D. A. T. New ◽  
P. T. Coppola ◽  
D. L. Cockroft

Rat embryos explanted at early head-fold stage and grown in vitro by improved culture methods were compared with littermates in vivo. Very similar rates of growth and differentiation were obtained over a period of 48 h, while the embryos developed to around the 25-somite stage.


1993 ◽  
Vol 7 (3) ◽  
pp. 259-264 ◽  
Author(s):  
M. Usami ◽  
K. Sakemi ◽  
H. Tabata ◽  
K. Kawashima ◽  
A. Takanaka

1989 ◽  
Vol 38 (2) ◽  
pp. 145-155 ◽  
Author(s):  
F.T. Geissler ◽  
F.B. Kuzan ◽  
E.M. Faustman ◽  
W.R. Henderson

2010 ◽  
Vol 115 (2) ◽  
pp. 577-588 ◽  
Author(s):  
Lina Xing ◽  
Yajun Xu ◽  
Yang Xiao ◽  
Lanqin Shang ◽  
Ran Liu ◽  
...  

1991 ◽  
Vol 19 (1) ◽  
pp. 94-98
Author(s):  
Erminio Giavini ◽  
Maria Luisa Broccia ◽  
Mariangela Prati

Various in vitro models have recently been tested for the assessment of developmental toxicity. Since the mechanisms involved in chemically-induced embryotoxicity are complex and numerous, a good in vitro assay must be able to detect developmental toxicants which act via most or all of these mechanisms. The rodent whole-embryo culture seems to fit this requirement, because it undergoes all of the fundamental processes of development. Also physical relationships between cells and tissues are maintained and morphogenesis can proceed normally. In fact, in vitro development of early post-implantation embryos closely parallels that occurring in utero. This assay appears to be particulary relevant for the detection of teratogenic and embryotoxic chemicals.


Sign in / Sign up

Export Citation Format

Share Document