scholarly journals Development of a Rapid Process Monitoring Method for Dry-Coated Tableting Process by Using Near-Infrared Spectroscopy

2011 ◽  
Vol 59 (7) ◽  
pp. 868-873 ◽  
Author(s):  
Masatomo Ito ◽  
Tatsuya Suzuki ◽  
Naoki Wakiyama ◽  
Hiroshi Teramoto ◽  
Etsuo Yonemochi ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Process Monitoring ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Monitoring Method ◽  
Rapid Process

scholarly journals Application of Near-Infrared Spectroscopy Analysis Technology to Total Nucleosides Quality Control in the Fermented Cordyceps Powder Production Process

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Tiannv Shi ◽  
Yongmei Guan ◽  
Lihua Chen ◽  
Shiyu Huang ◽  
Weifeng Zhu ◽  
...  
Keyword(s):  
Quality Control ◽  
Infrared Spectroscopy ◽  
Production Process ◽  
Process Monitoring ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Powder Preparation ◽  
Spectroscopy Analysis ◽  
Online Process Monitoring ◽  
Online Process

Product quality control is a prerequisite for ensuring safety, effectiveness, and stability. However, because of the different strain species and fermentation processes, there was a significant difference in quality. As a result, they should be clearly distinguished in clinical use. Among them, the fermentation process is critical to achieving consistent product quality. This study aims to introduce near-infrared spectroscopy analysis technology into the production process of fermented Cordyceps powder, including strain culture, strain passage, strain fermentation, strain filtration, strain drying, strain pulverizing, and strain mixing. First, high performance liquid chromatography (HPLC) was used to measure the total nucleosides content in the production process of 30 batches of fermented Cordyceps powder, including uracil, uridine, adenine, guanosine, adenosine, and the process stability and interbatch consistency were analyzed with traditional Chinese medicine (TCM) fingerprinting, followed by the near-infrared spectroscopy (NIRS) combined with partial least squares regression (PLSR) to establish a quantitative analysis model of total nucleosides for online process monitoring of fermented Cordyceps powder preparation products. The model parameters indicate that the established model with good robustness and high measurement precision. It further clarifies that the model can be used for online process monitoring of fermented Cordyceps powder preparation products.

scholarly journals Real-time monitoring of granule properties during high shear wet granulation by near-infrared spectroscopy with a chemometrics approach

RSC Advances ◽  
2017 ◽  
Vol 7 (61) ◽  
pp. 38307-38317 ◽  
Author(s):  
F. Shikata ◽  
S. Kimura ◽  
Y. Hattori ◽  
M. Otsuka
Keyword(s):  
Infrared Spectroscopy ◽  
Real Time ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Wet Granulation ◽  
High Shear ◽  
Monitoring Method ◽  
Granulation Process ◽  
High Shear Wet Granulation ◽  
Granule Properties

An in-line near-infrared spectroscopy monitoring method was developed for analyzing granule properties during a high shear wet granulation process.

scholarly journals Multiangle near infrared spectroscopy associated with common components and specific weights analysis for in line monitoring

2019 ◽  
Vol 27 (2) ◽  
pp. 134-146 ◽  
Author(s):  
M Rey-Bayle ◽  
R Bendoula ◽  
N Caillol ◽  
J-M Roger
Keyword(s):  
Infrared Spectroscopy ◽  
Process Monitoring ◽  
Near Infrared Spectroscopy ◽  
Oil Recovery ◽  
Near Infrared ◽  
Specific Weight ◽  
Precipitation Reaction ◽  
First Case ◽  
Weight Analysis ◽  
Common Components

Near infrared spectroscopy offers a number of important advantages for process monitoring. In addition to its numerous practical advantages, an important reason to use near infrared spectroscopy for process monitoring is its ability to supply versatile and multivariate information. However, in heterogeneous samples the interaction of light is complex and includes transmission, absorption, and scattering simultaneously which all affect spectra. The measurement of the signal at one point may be insufficient. A solution is to measure the medium at several points and to use specific multivariate analysis. In our study we propose to associate multipoint measurements with a common components and specific weight analysis. We monitored two media online by angular multipoint near infrared spectroscopy. For the first medium, in which only the scattering varies over time, the precipitation of silica was chosen to illustrate such a medium. For the second medium, both scattering and absorption vary, whereby microemulsions implemented for enhanced oil recovery illustrate this medium. The results showed, by combining multiangle measurements to common components and specific weight analysis, the interest of measuring at different angles. In the first case, two scattering regimes have been identified and it was possible to access the anisotropy coefficient during the silica precipitation reaction. In the second case study, on microemulsions, it was possible to identify the different phases and to separate the phenomena related to absorption and those related to diffusion. These encouraging results validate the interest of coupling multiangle measurements with multivariate multiblock analysis tools.

Monitoring Method for Brain Edema Based on Near-infrared Spectroscopy

2010 ◽  
Vol 39 (12) ◽  
pp. 2123-2128
Author(s):  
刘兴 LIU Xing ◽  
李韪韬 LI Wei-tao ◽  
钱志余 QIAN Zhi-yu ◽  
张建华 ZHANG Jian-hua
Keyword(s):  
Infrared Spectroscopy ◽  
Brain Edema ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Monitoring Method

scholarly journals Partial Least Squares Model based Process Monitoring using Near Infrared Spectroscopy

2013 ◽  
Vol 57 (1–2) ◽  
pp. 15
Author(s):  
Tibor Kulcsár ◽  
Gábor Sárossy ◽  
Gábor Bereznai ◽  
Róbert Auer ◽  
János Abonyi
Keyword(s):  
Infrared Spectroscopy ◽  
Least Squares ◽  
Partial Least Squares ◽  
Process Monitoring ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Model Based ◽  
Partial Least Squares Model
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