scholarly journals Scavenging Effects of Metal Complexes of Water-Soluble Thiacalix[4]arenetetrasulfonate on Superoxide Anion Radicals

2010 ◽  
Vol 58 (12) ◽  
pp. 1576-1581 ◽  
Author(s):  
Junichi Odo ◽  
Ayumi Kimura ◽  
Atsushi Matsu-ura ◽  
Yuki Ohnishi ◽  
Yoshiro Saeki ◽  
...  
2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Jianfeng Wang ◽  
Xiaoxiao Li ◽  
Yufeng He ◽  
Pengfei Song ◽  
Rong-Min Wang

To address the problem of limited application of natural SOD, the development of SOD mimic enzymes is of great importance for bioantioxidation. Herein, we report on a new type of biopolymer antioxidant with excellent scavenging activity for O2•-, keratin-glycine metal complexes (FK-GlyM, M = Zn, Cu, Mn, Ni). They are prepared by feather keratin firstly combined with glycine and then metal ions. Using FT-IR, TG, CD, and SEM, the performance of the obtained complexes (FK-GlyM) for scavenging O2•- is analysed and investigated. Importantly, the scavenging activity of FK-GlyCu is excellent in all FK-GlyM, and FK-GlyCu60 has the most excellent anti-O2•- activity in all FK-GlyCux, of which EC50 and degree of simulation were, respectively, up to 4.5×10-3±0.0012 μmol/L and 911.1% compared with nature Cu, Zn-SOD. Finally, its mechanism was also discussed. In summary, this method about the simulation strategies will provide a novel idea for exploiting new-type biocompatible and highly reactive antioxidants.


FEBS Letters ◽  
2010 ◽  
Vol 584 (13) ◽  
pp. 2816-2820 ◽  
Author(s):  
Yohei Miyamoto ◽  
Yasunori Iwao ◽  
Yuka Tasaki ◽  
Keizo Sato ◽  
Yu Ishima ◽  
...  

2017 ◽  
Vol 19 (9) ◽  
pp. 1176-1184 ◽  
Author(s):  
Yingfei Wang ◽  
Wen Deng ◽  
Fengliang Wang ◽  
Yuehan Su ◽  
Yiping Feng ◽  
...  

ROS play a key role in the photolysis of KET under simulated sunlight irradiation and the photoproducts may still have toxicity.


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