scholarly journals Novel Bile Acids from Bear Bile Powder and Bile of Geese

2009 ◽  
Vol 57 (5) ◽  
pp. 528-531 ◽  
Author(s):  
Dan Bi ◽  
Xing-Yun Chai ◽  
Yue-Lin Song ◽  
Yu Lei ◽  
Peng-Fei Tu
Keyword(s):  
Bile Acids ◽  
Bear Bile ◽  
Bear Bile Powder

ChemInform Abstract: Novel Bile Acids from Bear Bile Powder and Bile of Geese

ChemInform ◽  
2009 ◽  
Vol 40 (43) ◽  
Author(s):  
Dan Bi ◽  
Xing-Yun Chai ◽  
Yue-Lin Song ◽  
Yu Lei ◽  
Peng-Fei Tu
Keyword(s):  
Bile Acids ◽  
Bear Bile ◽  
Bear Bile Powder

Studies on Bile Acids in Bear Bile*

1973 ◽  
Vol 74 (3) ◽  
pp. 489-495 ◽  
Author(s):  
Keiko KUROZUMI ◽  
Teruo HARANO ◽  
Kazumi YAMASAKI ◽  
Yoshikazu AYAKI
Keyword(s):  
Bile Acids ◽  
Bear Bile

Identification and quantitation of bile acids in bear bile by HPLC

2020 ◽  
Vol 8 (4) ◽  
Author(s):  
D.-L. Lin ◽  
H.-C. Chang ◽  
C.-Y. Chen
Keyword(s):  
Bile Acids ◽  
Bear Bile

Rapid chemical analysis of bear bile: 5 minute separation and quantitation of bile acids using UHPLC–qTOF-MS

2014 ◽  
Vol 6 (2) ◽  
pp. 596-601 ◽  
Author(s):  
Xue Qiao ◽  
Wei Song ◽  
Xiong-hao Lin ◽  
Qi Wang ◽  
Tao Bo ◽  
...  
Keyword(s):  
Chemical Analysis ◽  
Bile Acids ◽  
Bear Bile

scholarly journals A Green Strategy to Produce Potential Substitute Resource for Bear Bile Using Engineered Saccharomyces Cerevisiae

2022 ◽  
Author(s):  
Lina Jin ◽  
Li Yang ◽  
Shujuan Zhao ◽  
Zhengtao Wang
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Green Manufacturing ◽  
Hydroxysteroid Dehydrogenase ◽  
Natural Material ◽  
Rare And Endangered ◽  
Potential Alternative ◽  
Engineered Saccharomyces Cerevisiae ◽  
Bear Bile ◽  
Bear Bile Powder

Abstract BackgroundBear bile powder is a precious natural material characterized by high content of tauroursodeoxycholic acid (TUDCA) at a ratio of 1.00–1.50 to taurochenodeoxycholic acid (TCDCA).ResultsIn this study, we use the crude enzymes from engineered Saccharomyces cerevisiae to directional convert TCDCA from chicken bile powder to TUDCA at the committed ratio in vitro. This S. cerevisiae strain was modified with heterologous 7α-hydroxysteroid dehydrogenase (7α-HSDH) and 7β-hydroxysteroid dehydrogenase (7β-HSDH) genes. S. cerevisiae host and HSDH gene combinatorial optimization and response surface methodology was applied to get the best engineered strain and the optimal biotransformation condition, respectively, under which 10.99 ± 0.16 g/L of powder products containing 36.73±6.68 % of TUDCA and 28.22±6.05 % of TCDCA were obtained using 12.00 g/L of chicken bile powder as substrate.ConclusionThis study provides a healthy and environmentally friendly way to produce potential alternative resource for bear bile powder from cheap and readily available chicken bile powder, and also gives a reference for the green manufacturing of other rare and endangered animal-derived valuable resource.

Metabolomics and proteomics approaches to characterize and assess proteins of bear bile powder for hepatitis C virus

2013 ◽  
Vol 11 (6) ◽  
pp. 653-665 ◽  
Author(s):  
Xi-Jun WANG ◽  
Guang-Li YAN ◽  
Ai-Hua ZHANG ◽  
Hui SUN ◽  
Cheng-Yu PIAO ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Bear Bile ◽  
Bear Bile Powder
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