scholarly journals Crystal Structures of Palladium(II) Ternary Complexes of 5-X-2-Aminobenzoic Acid with 1,10-Phenanthroline and Their Interaction with Calf Thymus DNA (Where X=Cl, Br and I)

2005 ◽  
Vol 53 (10) ◽  
pp. 1291-1295 ◽  
Author(s):  
Yue Wang ◽  
Nobuo Okabe ◽  
Mamiko Odoko
Keyword(s):  
Crystal Structures ◽  
Ternary Complexes ◽  
Calf Thymus Dna ◽  
Aminobenzoic Acid ◽  
Calf Thymus

Cu(ii) and Co(ii) ternary complexes of quinolone antimicrobial drug enoxacin and levofloxacin: structure and biological evaluation

RSC Advances ◽  
2014 ◽  
Vol 4 (66) ◽  
pp. 35193-35204 ◽  
Author(s):  
Wan-Yun Huang ◽  
Ji Li ◽  
Shi-Lin Kong ◽  
Zhong-Chang Wang ◽  
Hai-Liang Zhu
Keyword(s):  
Biological Evaluation ◽  
Ternary Complexes ◽  
Antimicrobial Drug ◽  
Calf Thymus Dna ◽  
Calf Thymus

Four novel metal–quinolone complexes tightly binded to calf-thymus DNA and exhibited good binding propensity to albumin protein.

scholarly journals Zinc(II) complexes of carboxamide derivatives: Crystal structures and interaction with calf thymus DNA

2015 ◽  
Vol 127 (10) ◽  
pp. 1747-1755 ◽  
Author(s):  
BIPLAB MONDAL ◽  
BUDDHADEB SEN ◽  
ENNIO ZANGRANDO ◽  
PABITRA CHATTOPADHYAY
Keyword(s):  
Crystal Structures ◽  
Calf Thymus Dna ◽  
Calf Thymus

Molecular Transformations in DNA under the Influence of UV-radiation

2020 ◽  
Vol 04 ◽  
Author(s):  
Vigen G. Barkhudaryan ◽  
Gayane V. Ananyan ◽  
Nelli H. Karapetyan
Keyword(s):  
Uv Radiation ◽  
Uv Irradiation ◽  
Absorption Spectroscopy ◽  
Calf Thymus Dna ◽  
Dilute Solutions ◽  
Concentrated Solutions ◽  
Buffer Solution ◽  
Low Concentration ◽  
Calf Thymus ◽  
Dna Solutions

Background: The processes of destruction and crosslinking of macromolecules occur simultaneously under the influence of ultraviolet (UV) radiation in synthetic polymers, dry DNA and their concentrated solutions. Objective: The effect of UV radiation on calf thymus DNA in dilute solutions subjected to UV- irradiation was studied in this work. Method: The calf thymus DNA was studied in dilute solutions using viscometry, absorption spectroscopy and electrophoresis. Results: It was shown, that at a low concentration of DNA in the buffer solution ([DNA] = 85 μg / ml) under the influence of UV radiation, the processes of destruction of macromolecules and an increase in their flexibility predominate, which is accompanied by a gradual decrease in the viscosity of their solution. In addition, due to the low concentration of the solution, intramolecular crosslinking of macromolecules predominates, which also reduces their size and, consequently, the viscosity of the solution. Conclusion: It was concluded, that in dilute DNA solutions, due to the predominance of the processes of intramolecular crosslinking of macromolecules over intermolecular, only constant processes of decreasing the sizes of DNA macromolecules occur. As a result, its solubility remains virtually unchanged during UV irradiation. The described comments are also excellently confirmed by the results of absorption spectroscopy and electrophoresis

Ce(IV)-mediated formation of benzenediazonium ion from a non-aminoazo dye, 1-phenylazo-2-hydroxy-naphthalene (Sudan I) and its binding to DNA

1989 ◽  
Vol 54 (7) ◽  
pp. 2021-2026
Author(s):  
Marie Stiborová ◽  
Befekadu Asfaw ◽  
Pavel Anzenbacher
Keyword(s):  
Azo Dyes ◽  
Acidic Medium ◽  
Model System ◽  
Calf Thymus Dna ◽  
Suitable Model ◽  
Principal Product ◽  
Calf Thymus ◽  
Sudan I ◽  
A Minor

Ce(IV) ions in acidic medium convert a carcinogenic non-aminoazo dye, 1-phenylazo-2-hydroxy-naphthalene (Sudan I) into an ultimate carcinogen, which binds to calf thymus DNA. The principal product of Sudan I oxidation by the Ce(IV) system is the benzenediazonium ion. A minor product is the dihydroxyderivative of Sudan I, 1-(4-hydroxyphenylazo)-2,6-dihydroxynaphthalene. Other minor coloured products (yellow and brown) were not identified. The principal product (the benzenediazonium ion) is responsible for the carcinogenicity of Sudan I, as it covalently binds to DNA. Ce(IV) ions in acidic medium represent a suitable model system, which imitates the activation route of carcinogenic azo dyes.

Investigation of Anti-Cancer Drug Nimustine Interaction with Calf Thymus DNA

MAPAN ◽  
2016 ◽  
Vol 31 (3) ◽  
pp. 169-175 ◽  
Author(s):  
Deepti Chadha ◽  
Shweta Agarwal ◽  
Ranjana Mehrotra
Keyword(s):  
Calf Thymus Dna ◽  
Cancer Drug ◽  
Calf Thymus ◽  
Anti Cancer

Studies on free radical scavenging, cancer cell antiproliferation, and calf thymus DNA interaction of Schiff bases

2017 ◽  
Vol 172 ◽  
pp. 129-138 ◽  
Author(s):  
Cleiton M. da Silva ◽  
Marina M. Silva ◽  
Fabiano S. Reis ◽  
Ana Lúcia T.G. Ruiz ◽  
João E. de Carvalho ◽  
...  
Keyword(s):  
Free Radical ◽  
Schiff Bases ◽  
Cancer Cell ◽  
Radical Scavenging ◽  
Dna Interaction ◽  
Free Radical Scavenging ◽  
Calf Thymus Dna ◽  
Calf Thymus
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