scholarly journals Efficient Synthesis of trans- or cis-4(5)-(5-Aminomethyltetrahydrofuran-2-yl)imidazoles via Diazafulvene Intermediates: Synthetic Approach toward Human Histamine H4-Ligands

2003 ◽  
Vol 51 (7) ◽  
pp. 832-837 ◽  
Author(s):  
Shinya Harusawa ◽  
Lisa Araki ◽  
Hirotaka Terashima ◽  
Makoto Kawamura ◽  
Seiichiro Takashima ◽  
...  
Keyword(s):  
Synthetic Approach ◽  
Efficient Synthesis ◽  
Human Histamine

Efficient Synthesis of trans- or cis-4(5)-(5-Aminomethyltetrahydrofuran-2-yl)imidazoles via Diazafulvene Intermediates: Synthetic Approach Toward Human Histamine H4-Ligands.

ChemInform ◽  
2003 ◽  
Vol 34 (50) ◽  
Author(s):  
Shinya Harusawa ◽  
Lisa Araki ◽  
Hirotaka Terashima ◽  
Makoto Kawamura ◽  
Seiichiro Takashima ◽  
...  
Keyword(s):  
Synthetic Approach ◽  
Efficient Synthesis ◽  
Human Histamine

scholarly journals Synthesis of the Tripeptide Antibiotic Resormycin

Synthesis ◽  
2017 ◽  
Vol 49 (24) ◽  
pp. 5351-5356 ◽  
Author(s):  
Loana Musso ◽  
Rahul Kaduskar ◽  
Andrea Pinto ◽  
Leonardo Scaglioni ◽  
Sabrina Dallavalle
Keyword(s):  
Amino Acid ◽  
Antifungal Activity ◽  
Late Stage ◽  
Biological Evaluation ◽  
Synthetic Approach ◽  
Efficient Synthesis ◽  
Hydroxy Amino Acid ◽  
Streptomyces Platensis ◽  
Hydroxy Amino ◽  
Modular Nature

A short and efficient synthesis of resormycin, a metabolite of Streptomyces platensis MJ953-SF5 with herbicidal and antifungal activity, is described. The key step in our synthetic approach is a late-stage stereospecific dehydration of a β-hydroxy amino acid to install the Z-olefin. Because of the modular nature of the synthesis, access to analogues for biological evaluation is readily available.

scholarly journals Study on the total synthesis of velbanamine: Chemoselective dioxygenation of alkenes with PIFA via a stop-and-flow strategy

2013 ◽  
Vol 9 ◽  
pp. 983-990 ◽  
Author(s):  
Huili Liu ◽  
Kuan Zheng ◽  
Xiang Lu ◽  
Xiaoxia Wang ◽  
Ran Hong
Keyword(s):  
Total Synthesis ◽  
Synthetic Approach ◽  
Efficient Synthesis

A “stop-and-flow” strategy was developed for the chemoselective dioxygenation of alkenes with a PIFA-initiated cyclization. This method is conceived for the desymmetrization of seco-diene, and a series of substituted 5-hydroxymethyl-γ-lactones were constructed after hydrolysis. This strategy also differentiates terminally substituted alkenes and constitutes a potentially novel synthetic approach for the efficient synthesis toward velbanamine.

Synthetic approach towards nakadomarin A: efficient synthesis of the central tetracyclic core

2001 ◽  
Vol 42 (47) ◽  
pp. 8345-8349 ◽  
Author(s):  
Toshiaki Nagata ◽  
Atsushi Nishida ◽  
Masako Nakagawa
Keyword(s):  
Synthetic Approach ◽  
Efficient Synthesis ◽  
Nakadomarin A ◽  
Tetracyclic Core

A novel synthetic approach to the cardiotoxin Batrachotoxin: An efficient synthesis of the AB ring system

1993 ◽  
Vol 34 (45) ◽  
pp. 7295-7298 ◽  
Author(s):  
Peter Hudson ◽  
Garry Pairaudeau ◽  
Philip J. Parsons ◽  
Archie W. Jahans ◽  
Michael G.B. Drew
Keyword(s):  
Ring System ◽  
Synthetic Approach ◽  
Efficient Synthesis ◽  
Ab Ring

A General Synthetic Approach to Novel Bis(tetracenyl) Aromatics for OFET Application

2005 ◽  
Vol 871 ◽  
Author(s):  
Michael Roth ◽  
Matthias Rehahn ◽  
Marcus Ahles ◽  
Roland Schmechel ◽  
Heinz von Seggern
Keyword(s):  
Carrier Mobility ◽  
Field Effect Transistors ◽  
Charge Carrier Mobility ◽  
Diels Alder ◽  
Synthetic Approach ◽  
Organic Field Effect Transistors ◽  
Efficient Synthesis ◽  
Synthetic Strategy ◽  
Broad Variety ◽  
Metal Catalyzed

AbstractA molecular tool box is presented, allowing the efficient synthesis of a broad variety of bis(tetracenyl) aromatics. These materials might be of considerable interest as semiconductors in organic field-effect transistors. The general synthetic strategy applied here involves Diels-Alder reactions of bromobenzocyclobutene derivatives and arene-1,4-endoxides[1], followed by transition-metal catalyzed condensation reactions of the formed 9-bromo-6,11-dihydrotetracene derivatives with aryldiboronic and -stannyl derivatives, respectively. In the final step, the resulting bis(dihydrotetracenyl) derivatives were dehydrogenated, giving the bis(tetracenyl) aromatics in good yields. They were characterized using NMR, UV-vis and mass spectrometry. Moreover, for some of these semiconductors the charge carrier mobility in thin film transistors has been determined.

A Concise and Efficient Synthesis of Isoindolin-1-ones. New Synthetic Approach to the Polycyclic Framework of Vitedoamine A.

ChemInform ◽  
2007 ◽  
Vol 38 (27) ◽  
Author(s):  
Marc Lamblin ◽  
Axel Couture ◽  
Eric Deniau ◽  
Pierre Grandclaudon
Keyword(s):  
Synthetic Approach ◽  
Efficient Synthesis

A concise and efficient synthesis of isoindolin-1-ones. New synthetic approach to the polycyclic framework of vitedoamine A

Tetrahedron ◽  
2007 ◽  
Vol 63 (12) ◽  
pp. 2664-2669 ◽  
Author(s):  
Marc Lamblin ◽  
Axel Couture ◽  
Eric Deniau ◽  
Pierre Grandclaudon
Keyword(s):  
Synthetic Approach ◽  
Efficient Synthesis

Efficient synthesis of (E)-2-nitromethylcinnamatesviaphosphine-catalyzed tandem α-addition and 1,3-rearrangement

2019 ◽  
Vol 6 (16) ◽  
pp. 2872-2876 ◽  
Author(s):  
Guofei Huang ◽  
Xiaoyu Ren ◽  
Chunhui Jiang ◽  
Jia-Hong Wu ◽  
Guowei Gao ◽  
...  
Keyword(s):  
Tandem Reaction ◽  
Synthetic Approach ◽  
Efficient Synthesis

An efficient synthetic approach for accessing (E)-2-nitromethylcinnamatesviaa phosphine-promoted tandem reaction between substituted nitromethanes and alkynes has been developed.

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