scholarly journals Inhibitory Effects of 2'-Hydroxychalcones on Rat Lens Aldose Reductase and Rat Platelet Aggregation.

2000 ◽  
Vol 48 (11) ◽  
pp. 1786-1789 ◽  
Author(s):  
Soon Sung LIM ◽  
Sang Hoon JUNG ◽  
Jun JI ◽  
Kuk Hyun SHIN ◽  
Sam Rok KEUM
Keyword(s):  
Platelet Aggregation ◽  
Aldose Reductase ◽  
Inhibitory Effects ◽  
Rat Lens Aldose Reductase

Inhibitory effect of pyridyloxy- or phenoxylphenoxyalkanate derivatives on rat lens aldose reductase and rat platelet aggregation

2004 ◽  
Vol 56 (7) ◽  
pp. 941-945 ◽  
Author(s):  
Soon Sung Lim ◽  
Kuk Hyun Shin ◽  
Sang Hoon Jung ◽  
Kye Jung Shin ◽  
Dong Chan Kim ◽  
...  
Keyword(s):  
Platelet Aggregation ◽  
Aldose Reductase ◽  
Inhibitory Effect ◽  
Rat Lens Aldose Reductase

Inhibitory effects ofGanoderma applanatum on rat lens aldose reductase and sorbitol accumulation in streptozotocin-induced diabetic rat tissues

2005 ◽  
Vol 19 (6) ◽  
pp. 477-480 ◽  
Author(s):  
Sang Hoon Jung ◽  
Yeon Sil Lee ◽  
Sang Hee Shim ◽  
Sanghyun Lee ◽  
Kuk Hyun Shin ◽  
...  
Keyword(s):  
Aldose Reductase ◽  
Diabetic Rat ◽  
Rat Tissues ◽  
Inhibitory Effects ◽  
Rat Lens Aldose Reductase

New Flavonol Oligoglycosides and Polyacylated Sucroses with Inhibitory Effects on Aldose Reductase and Platelet Aggregation from the Flowers ofPrunus mume1

2002 ◽  
Vol 65 (8) ◽  
pp. 1151-1155 ◽  
Author(s):  
Masayuki Yoshikawa ◽  
Toshiyuki Murakami ◽  
Tomoko Ishiwada ◽  
Toshio Morikawa ◽  
Masatomo Kagawa ◽  
...  
Keyword(s):  
Platelet Aggregation ◽  
Aldose Reductase ◽  
Inhibitory Effects

Antidiabetogenic constituents from several natural medicines

2002 ◽  
Vol 74 (7) ◽  
pp. 1301-1308 ◽  
Author(s):  
Hisashi Matsuda ◽  
Toshio Morikawa ◽  
Masayuki Yoshikawa
Keyword(s):  
Aldose Reductase ◽  
Serum Glucose ◽  
Inhibitory Effects ◽  
Structural Requirements ◽  
Traditional Medicines ◽  
Glucose Levels ◽  
Rat Lens Aldose Reductase ◽  
Inhibitory Activities ◽  
Natural Medicines ◽  
Salacia Reticulata

In the course of our studies on antidiabetogenic and antidiabetic principles of natural medicines and medicinal foodstuffs, we have isolated salacinol and kotalanol with unique thiosugar sulfonium sulfate inner salt structures from the antidiabetic Ayurvedic traditional medicines, Salacia reticulata and S. oblonga. Salacinol and kotalanol showed potent inhibitory activities against intestinal α-glucosidase, and also inhibitory effects of salacinol on the increase in serum glucose levels in maltose- and sucrose-loaded rats were found to be more potent than those of acarbose. In addition, various flavonoids with potent inhibitory activities against rat lens aldose reductase such as quercitrin desmanthin-1 and guaijaverin were isolated from Myrcia multiflora and several natural medicines, and some structural requirements of flavonoids for aldose reductase inhibitory activity were clarified.

Rat lens aldose reductase inhibitory activity of Aralia continentalis

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
JP Rodriguez ◽  
S Cho ◽  
J Lee ◽  
KH Lee ◽  
T Jin ◽  
...  
Keyword(s):  
Aldose Reductase ◽  
Inhibitory Activity ◽  
Aralia Continentalis ◽  
Rat Lens Aldose Reductase

The Effects of Brinolase (Fibrinolytic Enzyme from Aspergillus Oryzae) on Platelet Aggregation of Dog and Man

1972 ◽  
Vol 28 (01) ◽  
pp. 031-048 ◽  
Author(s):  
W. H. E Roschlau ◽  
R Gage
Keyword(s):  
Platelet Aggregation ◽  
Aspergillus Oryzae ◽  
Degradation Products ◽  
Blood Platelet ◽  
Human Platelets ◽  
Fibrinolytic Enzyme ◽  
Inhibitory Effects ◽  
Blood Platelet Aggregation

SummaryInhibition of blood platelet aggregation by brinolase (fibrinolytic enzyme from Aspergillus oryzae) has been demonstrated with human platelets in vitro and with dog platelets in vivo and in vitro, using both ADP and collagen as aggregating stimuli. It is suggested that the optimal inhibitory effects of brinolase occur indirectly through the generation of plasma fibrinogen degradation products, without compromising platelet viability, rather than by direct proteolysis of platelet structures.

scholarly journals Amide Derivatives of Ginkgolide B and Their Inhibitory Effects on PAF-Induced Platelet Aggregation

ACS Omega ◽  
2021 ◽  
Author(s):  
Qiang Shang ◽  
Xiaobo Zhou ◽  
Ming-Rong Yang ◽  
Jing-Guang Lu ◽  
Yu Pan ◽  
...  
Keyword(s):  
Platelet Aggregation ◽  
Ginkgolide B ◽  
Inhibitory Effects ◽  
Amide Derivatives ◽  
Derivatives Of
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