Synthesis of (10Z)- and (10E)-19-Fluoro-1.ALPHA.,25-dihydroxyvitamin D3. Compounds to Probe Vitamin D Conformation in Receptor Complex by 19F-NMR.

Masato SHIMIZU; Yukiko IWASAKI; Akiko OHNO; Sachiko YAMADA

doi:10.1248/cpb.48.1484

Synthesis of (10Z)- and (10E)-19-Fluoro-1.ALPHA.,25-dihydroxyvitamin D3. Compounds to Probe Vitamin D Conformation in Receptor Complex by 19F-NMR.

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.48.1484 ◽

2000 ◽

Vol 48 (10) ◽

pp. 1484-1493 ◽

Cited By ~ 12

Author(s):

Masato SHIMIZU ◽

Yukiko IWASAKI ◽

Akiko OHNO ◽

Sachiko YAMADA

Keyword(s):

Vitamin D ◽

19F Nmr ◽

Receptor Complex ◽

Dihydroxyvitamin D3

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ChemInform Abstract: Synthesis of (10Z)- and (10E)-19-Fluoro-1α,25-dihydroxyvitamin D3: Compounds to Probe Vitamin D Conformation in Receptor Complex by 19F NMR.

ChemInform ◽

10.1002/chin.200112221 ◽

2001 ◽

Vol 32 (12) ◽

pp. no-no

Author(s):

Masato Shimizu ◽

Yukiko Iwasaki ◽

Akiko Ohno ◽

Sachiko Yamada

Keyword(s):

Vitamin D ◽

19F Nmr ◽

Receptor Complex ◽

Dihydroxyvitamin D3

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Fluorinated Vitamin D Analogs to Probe the Conformation of Vitamin D in Its Receptor Complex: 19F-NMR Studies and Biological Activity

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.50.475 ◽

2002 ◽

Vol 50 (4) ◽

pp. 475-483 ◽

Cited By ~ 11

Author(s):

Akiko Ohno ◽

Masato Shimizu ◽

Sachiko Yamada

Keyword(s):

Vitamin D ◽

Biological Activity ◽

19F Nmr ◽

Receptor Complex ◽

Nmr Studies ◽

Vitamin D Analogs

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25S-Adamantyl-23-yne-26,27-dinor-1α,25-dihydroxyvitamin D3: Synthesis, Tissue Selective Biological Activities, and X-ray Crystal Structural Analysis of Its Vitamin D Receptor Complex

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.8b00427 ◽

2018 ◽

Vol 61 (15) ◽

pp. 6658-6673 ◽

Cited By ~ 3

Author(s):

Rocio Otero ◽

Michiyasu Ishizawa ◽

Nobutaka Numoto ◽

Teikichi Ikura ◽

Nobutoshi Ito ◽

...

Keyword(s):

Vitamin D ◽

Structural Analysis ◽

Vitamin D Receptor ◽

Biological Activities ◽

Receptor Complex ◽

Dihydroxyvitamin D3 ◽

X Ray ◽

Crystal Structural

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4,4-Difluoro-1α,25-dihydroxyvitamin D3: Analog to probe A-ring conformation in vitamin D-receptor complex

Tetrahedron Letters ◽

10.1016/s0040-4039(99)00030-1 ◽

1999 ◽

Vol 40 (9) ◽

pp. 1697-1700 ◽

Cited By ~ 10

Author(s):

Masato Shimizu ◽

Yukiko Iwasaki ◽

Sachiko Yamada

Keyword(s):

Vitamin D ◽

Vitamin D Receptor ◽

Receptor Complex ◽

Ring Conformation ◽

Dihydroxyvitamin D3

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Structure-function studies of 1,25-dihydroxyvitamin D3 and the vitamin D endocrine system. 1,25-dihydroxy-pentadeuterio-previtamin D3 (as a 6-s-cis analog) stimulates nongenomic but not genomic biological responses

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)85175-x ◽

1993 ◽

Vol 268 (19) ◽

pp. 13811-13819

Author(s):

A.W. Norman ◽

W.H. Okamura ◽

M.C. Farach-Carson ◽

K. Allewaert ◽

D. Branisteanu ◽

...

Keyword(s):

Vitamin D ◽

Structure Function ◽

Endocrine System ◽

Dihydroxyvitamin D3 ◽

1,25 Dihydroxyvitamin D3 ◽

Biological Responses

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Presence of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 24-hydroxylase in vitamin D target cells of rat yolk sac.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)33881-x ◽

1982 ◽

Vol 257 (18) ◽

pp. 10715-10721

Author(s):

J L Danan ◽

A C Delorme ◽

H Mathieu

Keyword(s):

Vitamin D ◽

Yolk Sac ◽

Target Cells ◽

Dihydroxyvitamin D3 ◽

1,25 Dihydroxyvitamin D3

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Interlaboratory comparison of 25-hydroxyvitamin D assays: Vitamin D Standardization Program (VDSP) Intercomparison Study 2 — Part 2 ligand binding assays — impact of 25-hydroxyvitamin D2 and 24R,25-dihydroxyvitamin D3 on assay performance

Analytical and Bioanalytical Chemistry ◽

10.1007/s00216-021-03577-0 ◽

2021 ◽

Author(s):

Stephen A. Wise ◽

Johanna E. Camara ◽

Carolyn Q. Burdette ◽

Grace Hahm ◽

Federica Nalin ◽

...

Keyword(s):

Vitamin D ◽

Ligand Binding ◽

Interlaboratory Comparison ◽

Binding Assays ◽

Dihydroxyvitamin D3 ◽

Hydroxyvitamin D ◽

Assay Performance ◽

25 Hydroxyvitamin D ◽

Intercomparison Study

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Mutant vitamin D receptors which confer hereditary resistance to 1,25-dihydroxyvitamin D3 in humans are transcriptionally inactive in vitro

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)47051-8 ◽

1989 ◽

Vol 264 (34) ◽

pp. 20230-20234

Author(s):

T Sone ◽

R.A. Scott ◽

M.R. Hughes ◽

P.J. Malloy ◽

D Feldman ◽

...

Keyword(s):

Vitamin D ◽

Dihydroxyvitamin D3 ◽

Vitamin D Receptors ◽

1,25 Dihydroxyvitamin D3

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ChemInform Abstract: Efficient and Versatile Synthesis of Novel 2α-Substituted 1α,25-Dihydroxyvitamin D3 Analogues and Their Docking to Vitamin D Receptors.

ChemInform ◽

10.1002/chin.200225209 ◽

2010 ◽

Vol 33 (25) ◽

pp. no-no

Author(s):

Yoshitomo Suhara ◽

Ken-ichi Nihei ◽

Masaaki Kurihara ◽

Atsushi Kittaka ◽

Kentaro Yamaguchi ◽

...

Keyword(s):

Vitamin D ◽

Dihydroxyvitamin D3 ◽

Vitamin D Receptors

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Induction of 1α,25-dihydroxyvitamin D3 synthesis in primary cultures of renal cells from vitamin D replete child

Bone ◽

10.1016/8756-3282(95)97377-r ◽

1995 ◽

Vol 17 (3) ◽

pp. 325

Author(s):

M.E. Hayes ◽

J.L. Berry ◽

C.C. Farquharson

Keyword(s):

Vitamin D ◽

Primary Cultures ◽

Renal Cells ◽

Dihydroxyvitamin D3

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