Studies on Nonpeptide Angiotensin II Receptor Antagonists. III. Synthesis and Biological Evaluation of 5-Alkylidene-3,5-dihydro-4H-imidazol-4-one Derivatives.

Toshio OKAZAKI; Kazumi KIKUCHI; Toshihiro WATANABE; Akira SUGA; Masayuki SHIBASAKI; Akira FUJIMORI; Osamu INAGAKI; Isao YANAGISAWA

doi:10.1248/cpb.46.777

Studies on Nonpeptide Angiotensin II Receptor Antagonists. III. Synthesis and Biological Evaluation of 5-Alkylidene-3,5-dihydro-4H-imidazol-4-one Derivatives.

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.46.777 ◽

1998 ◽

Vol 46 (5) ◽

pp. 777-781 ◽

Cited By ~ 9

Author(s):

Toshio OKAZAKI ◽

Kazumi KIKUCHI ◽

Toshihiro WATANABE ◽

Akira SUGA ◽

Masayuki SHIBASAKI ◽

...

Keyword(s):

Angiotensin Ii ◽

Biological Evaluation ◽

Angiotensin Ii Receptor ◽

Angiotensin Ii Receptor Antagonists ◽

Receptor Antagonists ◽

Synthesis And Biological Evaluation

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ChemInform Abstract: Nonpeptide Angiotensin II Receptor Antagonists. Part 4. Synthesis and Biological Evaluation of 4-Acrylamide-1H-imidazole Derivatives.

ChemInform ◽

10.1002/chin.199848121 ◽

2010 ◽

Vol 29 (48) ◽

pp. no-no

Author(s):

T. OKAZAKI ◽

T. WATANABE ◽

K. KIKUCHI ◽

A. SUGA ◽

M. SHIBASAKI ◽

...

Keyword(s):

Angiotensin Ii ◽

Biological Evaluation ◽

Angiotensin Ii Receptor ◽

Angiotensin Ii Receptor Antagonists ◽

Receptor Antagonists ◽

Imidazole Derivatives ◽

Synthesis And Biological Evaluation

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Synthesis and biological evaluation of new fluorine substituted derivatives as angiotensin II receptor antagonists with anti-hypertension and anti-tumor effects

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2012.09.065 ◽

2012 ◽

Vol 20 (24) ◽

pp. 7101-7111 ◽

Cited By ~ 19

Author(s):

Ya-jing Da ◽

Wei-dong Yuan ◽

Ting Xin ◽

Yong-yan Nie ◽

Ying Ye ◽

...

Keyword(s):

Angiotensin Ii ◽

Biological Evaluation ◽

Angiotensin Ii Receptor ◽

Angiotensin Ii Receptor Antagonists ◽

Receptor Antagonists ◽

Synthesis And Biological Evaluation

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ChemInform Abstract: Studies on Nonpeptide Angiotensin II Receptor Antagonists. Part 2. Synthesis and Biological Evaluation of 5H-Pyrazolo[1,5-b][1,2,4]triazole Derivatives with a C-Linked Oxygen Functional Group at the 6-Position.

ChemInform ◽

10.1002/chin.199828164 ◽

2010 ◽

Vol 29 (28) ◽

pp. no-no

Author(s):

T. OKAZAKI ◽

A. SUGA ◽

T. WATANABE ◽

K. KIKUCHI ◽

H. KURIHARA ◽

...

Keyword(s):

Angiotensin Ii ◽

Functional Group ◽

Biological Evaluation ◽

Angiotensin Ii Receptor ◽

Oxygen Functional Group ◽

Angiotensin Ii Receptor Antagonists ◽

Receptor Antagonists ◽

Triazole Derivatives ◽

Synthesis And Biological Evaluation

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Synthesis and biological evaluation of some new benzimidazoles derivatives 4'-{5-amino-2-[2-substituted-phenylamino)-phenyl-methyl]-benzimidazol-1 ylmethyl}-biphenyl-2-carboxylic acid: Nonpeptide angiotensin II receptor antagonists.

International Journal of Drug Delivery ◽

10.5138/ijdd.2010.0975.0215.02038 ◽

2010 ◽

Vol 2 (3) ◽

pp. 265-277 ◽

Cited By ~ 6

Author(s):

Mukesh C. Sharma ◽

Dharm V. Kohli ◽

Smita Sharma

Keyword(s):

Angiotensin Ii ◽

Carboxylic Acid ◽

Biological Evaluation ◽

Angiotensin Ii Receptor ◽

Angiotensin Ii Receptor Antagonists ◽

Receptor Antagonists ◽

Synthesis And Biological Evaluation

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Studies on Nonpeptide Angiotensin II Receptor Antagonists. II. Synthesis and Biological Evaluation of 5H-Pyrazolo(1,5-b)(1,2,4)triazole Derivatives with a C-Linked Oxygen Functional Group at the 6-Position.

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.46.287 ◽

1998 ◽

Vol 46 (2) ◽

pp. 287-293 ◽

Cited By ~ 5

Author(s):

Toshio OKAZAKI ◽

Akira SUGA ◽

Toshihiro WATANABE ◽

Kazumi KIKUCHI ◽

Hiroyuki KURIHARA ◽

...

Keyword(s):

Angiotensin Ii ◽

Functional Group ◽

Biological Evaluation ◽

Angiotensin Ii Receptor ◽

Oxygen Functional Group ◽

Angiotensin Ii Receptor Antagonists ◽

Receptor Antagonists ◽

Triazole Derivatives ◽

Synthesis And Biological Evaluation

Download Full-text

Synthesis and biological evaluation of novel potent angiotensin II receptor antagonists with anti-hypertension effect

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2012.02.003 ◽

2012 ◽

Vol 20 (8) ◽

pp. 2747-2761 ◽

Cited By ~ 7

Author(s):

Yong-yan Nie ◽

Ya-jing Da ◽

Hao Zheng ◽

Xiao-xia Yang ◽

Lin Jia ◽

...

Keyword(s):

Angiotensin Ii ◽

Biological Evaluation ◽

Angiotensin Ii Receptor ◽

Angiotensin Ii Receptor Antagonists ◽

Receptor Antagonists ◽

Synthesis And Biological Evaluation

Download Full-text

ChemInform Abstract: Studies on Nonpeptide Angiotensin II Receptor Antagonists. Part 1. Synthesis and Biological Evaluation of Pyrazolo[1,5-b][1,2,4]triazole Derivatives with Alkyl Substituents.

ChemInform ◽

10.1002/chin.199828312 ◽

2010 ◽

Vol 29 (28) ◽

pp. no-no

Author(s):

T. OKAZAKI ◽

A. SUGA ◽

T. WATANABE ◽

K. KIKUCHI ◽

H. KURIHARA ◽

...

Keyword(s):

Angiotensin Ii ◽

Biological Evaluation ◽

Angiotensin Ii Receptor ◽

Angiotensin Ii Receptor Antagonists ◽

Receptor Antagonists ◽

Triazole Derivatives ◽

Synthesis And Biological Evaluation

Download Full-text

Studies on Nonpeptide Angiotensin II Receptor Antagonists. IV. Synthesis and Biological Evaluation of 4-Acrylamide-1H-imidazole Derivatives.

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.46.973 ◽

1998 ◽

Vol 46 (6) ◽

pp. 973-981 ◽

Cited By ~ 3

Author(s):

Toshio OKAZAKI ◽

Toshihiro WATANABE ◽

Kazumi KIKUCHI ◽

Akira SUGA ◽

Masayuki SHIBASAKI ◽

...

Keyword(s):

Angiotensin Ii ◽

Biological Evaluation ◽

Angiotensin Ii Receptor ◽

Angiotensin Ii Receptor Antagonists ◽

Receptor Antagonists ◽

Imidazole Derivatives ◽

Synthesis And Biological Evaluation

Download Full-text

ChemInform Abstract: Nonpeptide Angiotensin II Receptor Antagonists. Part 3. Synthesis and Biological Evaluation of 5-Alkylidene-3,5-dihydro-4H-imidazol-4-one Derivatives.

ChemInform ◽

10.1002/chin.199847135 ◽

2010 ◽

Vol 29 (47) ◽

pp. no-no

Author(s):

T. OKAZAKI ◽

K. KIKUCHI ◽

T. WATANABE ◽

A. SUGA ◽

M. SHIBASAKI ◽

...

Keyword(s):

Angiotensin Ii ◽

Biological Evaluation ◽

Angiotensin Ii Receptor ◽

Angiotensin Ii Receptor Antagonists ◽

Receptor Antagonists ◽

Synthesis And Biological Evaluation

Download Full-text

Studies on Nonpeptide Angiotensin II Receptor Antagonists. I. Synthesis and Biological Evaluation of Pyrazolo(1,5-b)(1,2,4)triazole Derivatives with Alkyl Substituents.

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.46.69 ◽

1998 ◽

Vol 46 (1) ◽

pp. 69-78 ◽

Cited By ~ 7

Author(s):

Toshio OKAZAKI ◽

Akira SUGA ◽

Toshihiro WATANABE ◽

Kazumi KIKUCHI ◽

Hiroyuki KURIHARA ◽

...

Keyword(s):

Angiotensin Ii ◽

Biological Evaluation ◽

Angiotensin Ii Receptor ◽

Angiotensin Ii Receptor Antagonists ◽

Receptor Antagonists ◽

Triazole Derivatives ◽

Synthesis And Biological Evaluation

Download Full-text