scholarly journals Binding of glycyrrhetinic acid to rat plasma, rat serum albumin, human serum, and human serum albumin.

1988 ◽  
Vol 36 (1) ◽  
pp. 440-443 ◽  
Author(s):  
SHIRO ISHIDA ◽  
TSUTOMU ICHIKAWA ◽  
YOKO SAKIYA
1985 ◽  
Vol 230 (3) ◽  
pp. 561-567 ◽  
Author(s):  
S Onishi ◽  
S Itoh ◽  
T Yamakawa ◽  
K Isobe ◽  
M Manabe ◽  
...  

It has been stated by McDonagh, Palma & Lightner [(1982) J. Am. Chem. Soc. 104, 6867-6871] that complexing of bilirubin with serum albumin has a marked species-dependent influence on bilirubin photoisomerization in vitro and in vivo. Therefore the kinetics for the quantitatively important reaction: (Formula: see text) of the photochemical interconversion between bilirubin and its photoisomers bound to human or rat serum albumin in aqueous solution, assayed by h.p.l.c., was used to elucidate the observed species-dependent difference. The relative rate constants for bilirubin bound to human serum albumin, except for k4, the rate of interconversion from (ZZ)-bilirubin into (EZ)-bilirubin, proved to be considerably larger than those for bilirubin bound to rat serum albumin. In accordance with these rate constants, the formation of photoisomers of bilirubin bound to human serum albumin, except for (EZ)-bilirubin, is very rapid and much greater than that for bilirubin bound to rat serum albumin.


2011 ◽  
Vol 95 (8) ◽  
pp. e81 ◽  
Author(s):  
Na Zheng ◽  
Shaohua Zhu ◽  
Liang Liu ◽  
Xiaojun Yu

1969 ◽  
Vol 45 (4) ◽  
pp. 489-493 ◽  
Author(s):  
P. W. NATHANIELSZ

SUMMARY Recently changes in plasma free fatty acids have been suggested as a possible regulator of the levels of free thyroxine in the plasma. Oleic acid has been shown to displace tri-iodothyronine from human serum, human serum albumin, rat serum, rabbit serum and guinea-pig serum. The extent of the displacement, much greater from human serum albumin than from whole serum, suggests that free fatty acid does not affect the globulin binding site. It would also appear that, in the rat, all the binding sites are sensitive to free fatty acids and hence there is probably only albumin binding in this species. The results with rabbit and guinea-pig serum were intermediate to those with human and rat serum. A significant rise in resin uptake of tri-iodothyronine in vitro occurred with an increase of free fatty acid level of 0·5 m-equiv./l., well within the physiological range.


1985 ◽  
Vol 33 (7) ◽  
pp. 3031-3033 ◽  
Author(s):  
TSUTOMU ICHIKAWA ◽  
SHIRO ISHIDA ◽  
YOKO SAKIYA ◽  
YASUFUMI SAWADA

1990 ◽  
Vol 11 (3) ◽  
pp. 373-385 ◽  
Author(s):  
Goro Kominami ◽  
Hiromi Kawamoto ◽  
Yasuo Murai ◽  
Masao Kono

1994 ◽  
Vol 29 (2) ◽  
pp. 303-321 ◽  
Author(s):  
Abdel Khalik El-Sebae ◽  
Mohamed M. Abou Zeid ◽  
Fawzia Abdel-Rahman ◽  
Mahmoud Saleh

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