scholarly journals Effect of grifolan on the ascites form of Sarcoma 180.

1987 ◽  
Vol 35 (6) ◽  
pp. 2576-2580 ◽  
Author(s):  
NAOHITO OHNO ◽  
YOSHIYUKI SUZUKI ◽  
KICHIRO SATO ◽  
SHOZO OIKAWA ◽  
TOSHIRO YADOMAE
Keyword(s):  
Sarcoma 180 ◽  
Ascites Form

Antitumor activity of 1,2-diaminocyclohexaneplatinum complexes against Sarcoma-180 ascites form

1978 ◽  
Vol 21 (12) ◽  
pp. 1315-1318 ◽  
Author(s):  
Yoshinori Kidani ◽  
Kenji Inagaki ◽  
Masaaki Iigo ◽  
Akio Hoshi ◽  
Kazuo Kuretani
Keyword(s):  
Antitumor Activity ◽  
Sarcoma 180 ◽  
Ascites Form

Optimal Conditions for Antitumor Activity of C. Parvum Against the Ascites Form of Sarcoma 180

1980 ◽  
Vol 2 (1) ◽  
pp. 99-112 ◽  
Author(s):  
R. Megirian ◽  
C. L. Astry ◽  
R. P. Spoor ◽  
L. D. Loose
Keyword(s):  
Antitumor Activity ◽  
Sarcoma 180 ◽  
Optimal Conditions ◽  
Ascites Form

Platinum Compounds as Stains for Electron Microscopy

1974 ◽  
Vol 32 ◽  
pp. 230-231
Author(s):  
S. K. Aggarwal ◽  
P. McAllister ◽  
R. W. Wagner ◽  
B. Rosenberg
Keyword(s):  
Electron Microscopy ◽  
Hela Cells ◽  
Uranyl Acetate ◽  
Sarcoma 180 ◽  
Platinum Compounds ◽  
Kb Cells ◽  
En Bloc ◽  
Human Lymphoma ◽  
Ultrathin Sections ◽  
Blue Coloration

Uranyl acetate has been used as an electron stain for en bloc staining as well as for staining ultrathin sections in conjunction with various lead stains (Fig. 1). Present studies reveal that various platinum compounds also show promise as electron stains. Certain platinum compounds have been shown to be effective anti-tumor agents. Of particular interest are the compounds with either uracil or thymine as one of the ligands (cis-Pt(II)-uracil; cis-Pt(II)-thymine). These compounds are amorphous, highly soluble in water and often exhibit an intense blue coloration. These compounds show enough electron density to be used as stains for electron microscopy. Most of the studies are based on various cell lines (human AV, cells, human lymphoma cells, KB cells, Sarcoma-180 ascites cells, chick fibroblasts and HeLa cells) while studies on tissue blocks are in progress.

Cytological changes induced by platinum-thymine in sarcoma-180 cells: Electron microscopy study

1990 ◽  
Vol 48 (3) ◽  
pp. 290-291
Author(s):  
Gustav Ofosu
Keyword(s):  
Mammalian Cells ◽  
Antitumor Agent ◽  
Microscopy Study ◽  
Electron Microscopy Study ◽  
Limiting Factor ◽  
Sarcoma 180 ◽  
Electron Microscopic ◽  
Cytological Changes

Platinum-thymine has been found to be a potent antitumor agent, which is quite soluble in water, and lack nephrotoxicity as the dose-limiting factor. The drug has been shown to interact with DNA and inhibits DNA, RNA and protein synthesis in mammalian cells in vitro. This investigation was undertaken to elucidate the cytotoxic effects of piatinum-thymine on sarcoma-180 cells in vitro ultrastructurally, Sarcoma-180 tumor bearing mice were treated with intraperitoneal injection of platinum-thymine 40mg/kg. A concentration of 60μg/ml dose of platinum-thymine was used in in vitro experiments. Treatments were at varying time intervals of 3, 7 and 21 days for in vivo experiments, and 30, 60 and 120 min., 6, 12, and 24th in vitro. Controls were not treated with platinum-thymine.Electron microscopic analyses of the treated cells in vivo and in vitro showed drastic cytotoxic effect.

scholarly journals Phosphorylation of Ribosomal Proteins in Sarcoma 180 Tumor Cells

1972 ◽  
Vol 247 (17) ◽  
pp. 5345-5350
Author(s):  
Lawrence Bitte ◽  
David Kabat
Keyword(s):  
Tumor Cells ◽  
Ribosomal Proteins ◽  
Sarcoma 180
Sign in / Sign up

Export Citation Format

Share Document