scholarly journals The behavior of 1,4-benzodiazepine drugs in acidic media. V. Kinetics of hydrolysis of flutazolam and haloxazolam in aqueous solution.

1986 ◽  
Vol 34 (1) ◽  
pp. 320-326 ◽  
Author(s):  
TOMONARI KUWAYAMA ◽  
YUKIHISA KURONO ◽  
TSUYUKO MURAMATSU ◽  
TAMOTSU YASHIRO ◽  
KEN IKEDA
Keyword(s):  
Aqueous Solution ◽  
Acidic Media ◽  
Kinetics Of Hydrolysis ◽  
Kinetics Of ◽  
Hydrolysis Of ◽  
Benzodiazepine Drugs

Stability of the Nerve Gas Antidote BIS (4-Hydroxyiminomethyl-1-Pyridinomethyl) Ether Dichloride (Toxogonin®)

1968 ◽  
Vol 2 (9) ◽  
pp. 234-243 ◽  
Author(s):  
Inga Christenson
Keyword(s):  
Aqueous Solution ◽  
Hydrochloric Acid ◽  
Sodium Hydroxide ◽  
Rate Constants ◽  
Kinetics Of Hydrolysis ◽  
Dilute Aqueous Solution ◽  
Nerve Gas ◽  
Ph Range ◽  
Kinetics Of ◽  
Hydrolysis Of

The products and kinetics of hydrolysis of the nerve gas antidote bis(4-hydroxyiminomethyl - 1 - pyridinemethyl) ether dichloride (Toxogonin ®) have been investigated. A survey of these studies is given: The hydrolytic reactions were studied in the pH range 1 M hydrochloric acid to 1 M sodium hydroxide at 25, 45, 75 and 85° C. Rate constants were determined in dilute aqueous solution, generally with an initial Toxogonin concentration of 0.01 mg per ml. In addition, a report is given concerning two-year storage of 25 percent (w/v) Toxogonin solutions at pH 2.5, 3.0 and 3.5. The solutions were stored in glass or polypropylene ampuls at 5, 15, 25 and 45°C. At 5 and 15C° decomposition was negligible, at 25 and 45 °C average decomposition was 1.5 percent and 3.3 percent, respectively.

scholarly journals Kinetics of hydrolysis of oxazolam in aqueous solution.

1984 ◽  
Vol 32 (3) ◽  
pp. 1080-1090 ◽  
Author(s):  
MASARU IKEDA ◽  
TSUNEJI NAGAI
Keyword(s):  
Aqueous Solution ◽  
Kinetics Of Hydrolysis ◽  
Kinetics Of ◽  
Hydrolysis Of

Kinetics of hydrolysis of ferric ion in dilute aqueous solution

1971 ◽  
Vol 75 (7) ◽  
pp. 929-932 ◽  
Author(s):  
Paul Hemmes ◽  
Larry D. Rich ◽  
David L. Cole ◽  
Edward M. Eyring
Keyword(s):  
Aqueous Solution ◽  
Ferric Ion ◽  
Kinetics Of Hydrolysis ◽  
Dilute Aqueous Solution ◽  
Kinetics Of ◽  
Hydrolysis Of
Sign in / Sign up

Export Citation Format

Share Document