scholarly journals Further analysis of multiple forms of rabbit hepatic glutathione S-transferase.

1986 ◽  
Vol 34 (7) ◽  
pp. 2919-2925 ◽  
Author(s):  
SHUICHI MIYAURA ◽  
HIDEO ISONO
1975 ◽  
Vol 60 (1) ◽  
pp. 153-161 ◽  
Author(s):  
Kazuaki KAMISAKA ◽  
William H. HABIG ◽  
Jeanne N. KETLEY ◽  
Irwin M. ARIAS ◽  
William B. JAKOBY

1985 ◽  
Vol 98 (1) ◽  
pp. 117-123 ◽  
Author(s):  
Takashi IGARASHI ◽  
Tetsuo SATOH ◽  
Keiko IWASHITA ◽  
Satoshi ONO ◽  
Koichi UENO ◽  
...  

The Lancet ◽  
1987 ◽  
Vol 329 (8536) ◽  
pp. 771-774 ◽  
Author(s):  
LaurenG. Allan ◽  
Jane Howie ◽  
AlistairF. Smith ◽  
AmandaJ. Hussey ◽  
GeoffreyJ. Beckett ◽  
...  

1988 ◽  
Vol 66 (8) ◽  
pp. 1048-1052 ◽  
Author(s):  
P. F. Bauman ◽  
T. K. Smith ◽  
T. M. Bray

Hepatic glutathione concentration and glutathione-dependent enzymes, glutathione S-transferase, glutathione peroxidase, and glutathione reductase, are important for protection against toxic compounds. Rats were fed diets containing 4, 7.5, 15, or 45% protein for 2 weeks. Glutathione and cysteine concentrations in rats fed the 4 and 7.5% protein diets were significantly lower (p < 0.05) than in rats fed the 15 and 45% protein diets. Glutathione S-transferase activity increased with increasing dietary protein. Glutathione peroxidase activity was significantly lower (p < 0.05) in rats fed 4 and 7.5% protein compared with rats fed 15 and 45% protein, whereas the activity of glutathione reductase was higher in rats fed 4 and 7.5% protein then in rats fed 15 or 45% protein. Dietary sulfur amino acids alone could account for the increase in glutathione concentration resulting from the increase in dietary protein from 7.5 to 15%. The limited availability of glutathione in animals fed the low protein diets could reduce the potential for detoxification of xenobiotics.


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