Physicochemical properties of amphoteric .BETA.-lactam antibiotics. IV. First- and second-order degradations of cefaclor and cefatrizine in aqueous solution and kinetic interpretation of the intestinal absorption and degradation of the concentrated antibiotics.

EMI NAKASHIMA; AKIRA TSUJI; MASATO NAKAMURA; TSUKINAKA YAMANA

doi:10.1248/cpb.33.2098

Physicochemical properties of amphoteric .BETA.-lactam antibiotics. IV. First- and second-order degradations of cefaclor and cefatrizine in aqueous solution and kinetic interpretation of the intestinal absorption and degradation of the concentrated antibiotics.

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.33.2098 ◽

1985 ◽

Vol 33 (5) ◽

pp. 2098-2106 ◽

Cited By ~ 10

Author(s):

EMI NAKASHIMA ◽

AKIRA TSUJI ◽

MASATO NAKAMURA ◽

TSUKINAKA YAMANA

Keyword(s):

Aqueous Solution ◽

Physicochemical Properties ◽

Intestinal Absorption ◽

Second Order ◽

Beta Lactam ◽

Beta Lactam Antibiotics

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Intestinal absorption of several .BETA.-lactam antibiotics. III. Competitive inhibition behavior among zwitterionic .BETA.-lactam antibiotics in the rat intestinal absorption.

Journal of Pharmacobio-Dynamics ◽

10.1248/bpb1978.5.555 ◽

1982 ◽

Vol 5 (8) ◽

pp. 555-563 ◽

Cited By ~ 18

Author(s):

KATSUMI MIYAZAKI ◽

KYOKO OHTANI ◽

KAZUTOSHI UMENIWA ◽

TAKAICHI ARITA

Keyword(s):

Intestinal Absorption ◽

Competitive Inhibition ◽

Beta Lactam ◽

Beta Lactam Antibiotics

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Intestinal absorption of several .BETA.-lactam antibiotics. II. Absorption characteristics of amino-penicillins and amino-cephalosporins.

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.27.2177 ◽

1979 ◽

Vol 27 (9) ◽

pp. 2177-2182 ◽

Cited By ~ 19

Author(s):

KAZUTOSHI UMENIWA ◽

OSAMU OGINO ◽

KATSUMI MIYAZAKI ◽

TAKAICHI ARITA

Keyword(s):

Intestinal Absorption ◽

Beta Lactam ◽

Beta Lactam Antibiotics ◽

Absorption Characteristics

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Characterization of the intestinal absorption of beta-lactam antibiotics in a PEPT1/MRP3 double-transfected cell line and by using the ussing chamber technique

Drug Metabolism and Pharmacokinetics ◽

10.1016/j.dmpk.2016.10.123 ◽

2017 ◽

Vol 32 (1) ◽

pp. S25

Author(s):

Markus Keiser ◽

Eva Mangelsen ◽

Tamara Petrikat ◽

Stefan Oswald

Keyword(s):

Intestinal Absorption ◽

Cell Line ◽

Ussing Chamber ◽

Beta Lactam ◽

Transfected Cell Line ◽

Beta Lactam Antibiotics ◽

Chamber Technique

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Studies on β-Lactam Antibiotics for Medicinal Purpose. IV. Stability of 6-[D (-)-α-(4-Ethyl-2, 3-dioxo-1-piperazinecarboxamido) phenylacetamido] penicillanic Acid (T-1220) in Aqueous Solution and Body Fluid

YAKUGAKU ZASSHI ◽

10.1248/yakushi1947.97.9_995 ◽

1977 ◽

Vol 97 (9) ◽

pp. 995-1001 ◽

Cited By ~ 4

Author(s):

ISAMU SAIKAWA ◽

SHUNTARO TAKANO ◽

CHOSAKU YOSHIDA ◽

EIJI SAITO ◽

TAKASHI YASUDA ◽

...

Keyword(s):

Aqueous Solution ◽

Body Fluid ◽

Beta Lactam ◽

Medicinal Purpose ◽

Beta Lactam Antibiotics ◽

Penicillanic Acid

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Studies on β-Lactam Antibiotics for Medicinal Purpose. XIV. Stability and Degradation Pattern of Sodium 7β-[(2R, 3S)-2-(4-Ethyl-2, 3-dioxo-1-piperazinecarboxamido)-3-hydroxybutanamido]-7α-methoxy-3-[(1-methyl-1H-tetrazol-5-yl) thiomethyl]-3-cephem-4-carboxylate (T-1982) in Aqueous Solution

YAKUGAKU ZASSHI ◽

10.1248/yakushi1947.103.1_62 ◽

1983 ◽

Vol 103 (1) ◽

pp. 62-72 ◽

Cited By ~ 1

Author(s):

SHUNTARO TAKANO ◽

MASARU TAI ◽

HIROSHI SAKAI ◽

ISAMU TAKAKURA ◽

HIROKAZU OCHIAI ◽

...

Keyword(s):

Aqueous Solution ◽

Beta Lactam ◽

Medicinal Purpose ◽

Beta Lactam Antibiotics ◽

Degradation Pattern

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Intestinal absorption of several .BETA.-lactam antibiotics. IV. Binding to the various components in the intestinal mucosa of rat and role in absorption process.

Journal of Pharmacobio-Dynamics ◽

10.1248/bpb1978.5.593 ◽

1982 ◽

Vol 5 (8) ◽

pp. 593-602 ◽

Cited By ~ 11

Author(s):

KATSUMI MIYAZAKI ◽

KEN ISEKI ◽

TAKAICHI ARITA

Keyword(s):

Intestinal Absorption ◽

Intestinal Mucosa ◽

Absorption Process ◽

Beta Lactam ◽

Beta Lactam Antibiotics

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Physicochemical properties of amphoteric .BETA.-lactam antibiotics. III. Stability, solubility, and dissolution behavior of cefatrizine and cefadroxil as a function of pH.

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.31.4057 ◽

1983 ◽

Vol 31 (11) ◽

pp. 4057-4069 ◽

Cited By ~ 8

Author(s):

AKIRA TSUJI ◽

EMI NAKASHIMA ◽

KAZUNORI NISHIDE ◽

YOSHIHARU DEGUCHI ◽

SHOICHIRO HAMANO ◽

...

Keyword(s):

Physicochemical Properties ◽

Dissolution Behavior ◽

Beta Lactam ◽

Beta Lactam Antibiotics

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Intestinal absorption of beta-lactam antibiotics and oligopeptides. Functional and stereospecific reconstitution of the oligopeptide transport system from rabbit small intestine

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1992.tb16713.x ◽

1992 ◽

Vol 204 (2) ◽

pp. 923-930 ◽

Cited By ~ 33

Author(s):

Werner KRAMER ◽

Frank GIRBIG ◽

Ulrike GUTJAHR ◽

Simone KOWALEWSKI ◽

Friedhelm ADAM ◽

...

Keyword(s):

Small Intestine ◽

Intestinal Absorption ◽

Transport System ◽

Beta Lactam ◽

Beta Lactam Antibiotics ◽

Rabbit Small Intestine ◽

Oligopeptide Transport System ◽

Oligopeptide Transport

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Enhanced small intestinal absorption of .BETA.-lactam antibiotics in rats in the presence of monodesmosides isolated from pericarps of Sapindus mukurossi (enmei-hi).

Journal of Pharmacobio-Dynamics ◽

10.1248/bpb1978.9.211 ◽

1986 ◽

Vol 9 (2) ◽

pp. 211-217 ◽

Cited By ~ 11

Author(s):

N YATA

Keyword(s):

Intestinal Absorption ◽

Beta Lactam ◽

Beta Lactam Antibiotics ◽

Small Intestinal ◽

Small Intestinal Absorption

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PS-6 and PS-7, new .BETA.-lactam antibiotics. Isolation, physicochemical properties and structures.

The Journal of Antibiotics ◽

10.7164/antibiotics.33.1128 ◽

1980 ◽

Vol 33 (10) ◽

pp. 1128-1137 ◽

Cited By ~ 18

Author(s):

NORIO SHIBAMOTO ◽

AKIHIKO KOKI ◽

MASAYOSHI NISHINO ◽

KOSUMI NAKAMURA ◽

KOHKI KIYOSHIMA ◽

...

Keyword(s):

Physicochemical Properties ◽

Beta Lactam ◽

Beta Lactam Antibiotics

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