Purification and some properties of ketone reductase forming an active metabolite of sodium 2-(4-(2-oxocyclopentylmethyl)phenyl)propionate dihydrate(loxoprofen sodium), a new anti-inflammatory agent, in rabbit liver cytosol.

1984 ◽  
Vol 32 (3) ◽  
pp. 1040-1048 ◽  
Author(s):  
YORIHISA TANAKA ◽  
YUKO NISHIKAWA ◽  
KEIICHI MATSUDA ◽  
MITSUO YAMAZAKI ◽  
RYOZO HAYASHI
Keyword(s):  
Active Metabolite ◽  
Rabbit Liver ◽  
Liver Cytosol ◽  
Inflammatory Agent ◽  
Loxoprofen Sodium ◽  
Anti Inflammatory

scholarly journals CS-600 a new anti-inflammatory agent III Stereospecific formation of an active metabolite by ketone reductase

Ensho ◽  
1983 ◽  
Vol 3 (2) ◽  
pp. 151-155
Author(s):  
Yorihisa Tanaka ◽  
Yuko Nishikawa ◽  
Shuji Kanno ◽  
Keiichi Matsuda ◽  
Mitsuo Yamazaki ◽  
...  
Keyword(s):  
Active Metabolite ◽  
Inflammatory Agent ◽  
Anti Inflammatory

Helenalin: An Anti-Inflammatory and Anti-Neoplastic Agent: A Review

2020 ◽  
Vol 16 (8) ◽  
pp. 1134-1146
Author(s):  
Priyanka Kriplani ◽  
Kumar Guarve ◽  
Uttam S. Baghel
Keyword(s):  
Rheumatoid Arthritis ◽  
Adverse Effects ◽  
Chronic Conditions ◽  
Review Article ◽  
Google Scholar ◽  
Medical Community ◽  
Inflammatory Agent ◽  
Skin Cancers ◽  
Medicinal Properties ◽  
Anti Inflammatory

Objective: Helenalin is a natural anti-inflammatory agent that is proving its efficacy to treat various medical conditions. Though many plants are proving their effectiveness but their mechanisms are still not well understood. The objective of the review is to summarize various mechanisms of helenalin to treat inflammatory disorders and cancers, adverse effects, and avenues of further research. Methods: Structured research was carried out including Pub med, Science direct Medline, Research Gate and Google Scholar to find all articles published on helenalin. Various keywords used were “helenalin”, “Arnica”, “cancer”, “anti-inflammatory”, “cardiovascular”, “IBD”, “pharmacokinetics” etc. The aim of the review was to find out the problem prevailing in the data published to date which will help the researchers to investigate the molecule clinically. Results: Seventy articles are included in the review. Helenalin is found to cure chronic conditions like rheumatoid arthritis, ulcers and malignancies like stomach, colon, breast, larynx, lung and skin cancers via multiple mechanisms. These diseases do not proceed via a unilateral pathway. So, it can be a useful molecule to treat numerous diseases. Conclusion: This review article will help us to systemically analyze the wealth of information concerning the medicinal properties of helenalin and to recognize the gaps which have vetoed its pervasive application in the medical community.

scholarly journals The potential effects of Centella asiatica ethanolic extracts as an anti-inflammatory agent through decreasing TNF-α expression in indomethacin-induced gastric ulcer model rats

2021 ◽  
Author(s):  
Priscilla Maiselina Sriepindonnta ◽  
Fatimah Nur Fitriani ◽  
Savannah Quila Thirza ◽  
Made Dinda Pratiwi ◽  
Dwi Evan Prima Putra Noviardi ◽  
...  
Keyword(s):  
Gastric Ulcer ◽  
Centella Asiatica ◽  
Inflammatory Agent ◽  
Tnf Α ◽  
Ethanolic Extracts ◽  
Ulcer Model ◽  
Anti Inflammatory

Beyond its anti‐migraine properties, sumatriptan is an anti‐inflammatory agent: A systematic review

2021 ◽  
Author(s):  
Moein Ala ◽  
Mehdi Ghasemi ◽  
Razieh Mohammad Jafari ◽  
Ahmad Reza Dehpour
Keyword(s):  
Systematic Review ◽  
Inflammatory Agent ◽  
Anti Inflammatory
Sign in / Sign up

Export Citation Format

Share Document