scholarly journals Chemical and biochemical studies on carbohydrate esters. XII. The phagocytic response of the reticuloendothelial system in mice following intraperitoneal administration of disaccharide esters of fatty acids.

1982 ◽  
Vol 30 (4) ◽  
pp. 1377-1380 ◽  
Author(s):  
YOSHIHIRO NISHIKAWA ◽  
RYOUTA TATEZAKI ◽  
HIROMITSU OHNO
Keyword(s):  
Fatty Acids ◽  
Intraperitoneal Administration ◽  
Reticuloendothelial System ◽  
Biochemical Studies ◽  
Carbohydrate Esters ◽  
Phagocytic Response

Oxygen-induced changes in pulmonary phospholipids in the rat

1975 ◽  
Vol 39 (5) ◽  
pp. 780-787 ◽  
Author(s):  
M. Valimaki ◽  
T. T. Pelliniemi ◽  
J. Niinikoski
Keyword(s):  
Fatty Acids ◽  
Lung Tissue ◽  
Liver Tissue ◽  
Unsaturated Fatty Acids ◽  
Intraperitoneal Administration ◽  
Phosphatidyl Glycerol ◽  
Rat Lungs ◽  
Specific Activities ◽  
Induced Changes ◽  
Alveolar Phospholipids

The composition and synthesis of alveolar and lung tissue phospholipids were investigated in normal and oxygen-poisoned rat lungs. Sixty-hour exposure to oxygen increased the total amount of phospholipids in the endobronchial extracts and lung tissue. Phosphatidyl glycerol was identified in both endobronchial extracts and lung tissue. The amount of unsaturated fatty acids in surfactant lecithin and phosphatidyl glycerol was slightly increased in oxygen-poisoned lungs whereas the composition of phospholipids in the endobronchial extracts was not affected by oxygen. After intraperitoneal administration of [32P]phosphate the specific activities of surfactant lecithin and phosphatidyl glycerol were clearly lower in oxygen-treated animals whereas the specific activities of lung tissue lecithin and phosphatidyl glycerol remained unaffected. The synthesis of lecithin from [14C]methionine through N-methyltransferase pathway was markedly depressed in lung slices but increased in liver tissue taken from oxygen-poisoned rats and incubated under oxygen indicating a difference between lung and liver methyltransferase enzymes. In conclusion, the present work suggests impaired synthesis and removal of alveolar phospholipids in oxygen-poisoned rats.

scholarly journals Chemical and biochemical studies on carbohydrate esters. XI. Antitumor effects of fatty acid monoesters of D-glucose.

1981 ◽  
Vol 29 (3) ◽  
pp. 880-883 ◽  
Author(s):  
YOSHIHIRO NISHIKAWA ◽  
KIMIHIRO YOSHIMOTO ◽  
KUMIKO ASHIZAWA ◽  
TETSURO IKEKAWA
Keyword(s):  
Fatty Acid ◽  
Antitumor Effects ◽  
Biochemical Studies ◽  
Carbohydrate Esters

Mixed Substrates: trans-and cis -[1-14C]Monounsaturated Fatty Acids with a Fairly Uniform Distribution of Positional Isomers

1978 ◽  
Vol 33 (9-10) ◽  
pp. 629-633 ◽  
Author(s):  
Ingolf Richter ◽  
Kumar D. Mukherjee ◽  
Nikolaus Weber
Keyword(s):  
Fatty Acids ◽  
Uniform Distribution ◽  
Catalytic Hydrogenation ◽  
Methyl Esters ◽  
Monounsaturated Fatty Acids ◽  
Positional Isomers ◽  
Mixed Substrates ◽  
Argentation Chromatography ◽  
Biochemical Studies ◽  
Hydrolysis Of

Abstract Simple methods are described for the preparation of trans-[1-14C]monounsaturated fatty acids and cis -[1-14C]monounsaturated fatty acids, each with a fairly uniform distribution of positional isomers, which can serve as mixed substrates in biochemical studies. Methyl trans- [1-14C] octadecenoates and methyl trans-[1-14C] eicosenoates are prepared by partial catalytic hydrogenation of methyl [1-14C] linolenate and methyl [1-14C] arachidonate, respectively, follow ed by argentation chromatography of the partially hydrogenated products. Methyl trans-[1-14C] octadecenoates and methyl trans-[1-14C] eicosenoates, thus obtained, yield the corresponding methyl cis-[1-14C] octadecenoates and methyl cis-[1-14C] eicosenoates, respectively, after trans-cis equilibration and argentation chromatography. Hydrolysis of each of these methyl esters yields the fatty acids.

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