scholarly journals Chemical modification of aminoglycoside antibiotics. Some N-alkyl derivatives of sorbistin A1 (P-2563 P) and butirosin A.

1979 ◽  
Vol 27 (1) ◽  
pp. 65-75 ◽  
Author(s):  
KIYOSHI NARA ◽  
KOUICHI YOSHIOKA ◽  
MAKOTO KIDA
Keyword(s):  
Chemical Modification ◽  
Aminoglycoside Antibiotics ◽  
Alkyl Derivatives ◽  
Derivatives Of

Aminoglycoside antibiotics: The formation and characterization of dihydrooxazine derivatives in the paromomycin series

1978 ◽  
Vol 56 (11) ◽  
pp. 1492-1499 ◽  
Author(s):  
Stephen Hanessian ◽  
Robert Massé ◽  
Goran Ekborg
Keyword(s):  
Chemical Modification ◽  
Zinc Chloride ◽  
Aminoglycoside Antibiotics ◽  
High Yield ◽  
Hydroxyl Groups ◽  
Model Studies ◽  
Derivatives Of ◽  
Excess Zinc ◽  
Chemical Evidence

Treatment of penta-N-benzyloxycarbonylparomomycin with benzaldehyde and excess zinc chloride gives a dibenzylidene derivative in high yield. This consists of the 4′,6′-O-benzylidene 4′′′,6′′′-N,O-benzylidene (dihydrooxazine) derivative of penta-N-benzyloxycarbonylparomomycin. Chemical evidence is presented to support this structure and model studies are reported for the formation of dihydrooxazine and oxazolidine derivatives of benzyloxycarbonylamino sugars containing suitably situated hydroxyl groups. The easily obtained dihydrooxazine derivative of paromomycin constitutes an interesting, preferentially blocked derivative, that is useful for the chemical modification of the parent antibiotic.

scholarly journals Chemical modification of erythromycins. II. Synthesis and antibacterial activity of O-alkyl derivatives of erythromycin A.

1990 ◽  
Vol 43 (3) ◽  
pp. 286-294 ◽  
Author(s):  
SHIGEO MORIMOTO ◽  
YOKO MISAWA ◽  
TAKASHI ADACHI ◽  
TAKATOSHI NAGATE ◽  
YOSHIAKI WATANABE ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Chemical Modification ◽  
Alkyl Derivatives ◽  
Erythromycin A ◽  
Derivatives Of

7-O-Alkyl derivatives of daunomycinone

1984 ◽  
Vol 49 (1) ◽  
pp. 313-319 ◽  
Author(s):  
Věra Přikrylová ◽  
Petr Sedmera ◽  
Josef V. Jizba ◽  
Jindřich Vokoun ◽  
Helena Lipavská ◽  
...  
Keyword(s):  
H Nmr ◽  
Toluenesulfonic Acid ◽  
Alkyl Derivatives ◽  
Derivatives Of

Reaction of daunomycinone (I) with alcohols and p-toluenesulfonic acid produces a mixture (~3 : 1) of its (7S)- and (7R)-O-alkyl derivatives II-IX. According to the 1H NMR evidence, the alicyclic ring exists in the 9H8 conformation in (7R)-O-alkyl derivatives, on the contrary to (7S)-epimers and 7-epi-daunomycinone that adopt the 8H9 conformation.

Polarized fluorescense of alkyl derivatives of fluorescein, MitoFluo and C8-Fl, in solutions with liposomes

2020 ◽  
Author(s):  
D.M. Beltukova ◽  
V.P. Belik ◽  
Y.N. Antonenko ◽  
A.A. Bogdanov ◽  
G.A. Korshunova ◽  
...  
Keyword(s):  
Alkyl Derivatives ◽  
Derivatives Of

Synthesis and reactivity of halide, hydride, and alkyl derivatives of (pentamethylcyclopentadienyl)(bisphosphine)iron(II)

1990 ◽  
Vol 9 (1) ◽  
pp. 260-265 ◽  
Author(s):  
Rocco A. Paciello ◽  
Juan M. Manriquez ◽  
John E. Bercaw
Keyword(s):  
Alkyl Derivatives ◽  
Derivatives Of

scholarly journals Chemical modification of herbimycin A. Synthesis and in vivo antitumor activities of halogenated and other related derivatives of herbimycin A.

1986 ◽  
Vol 39 (3) ◽  
pp. 415-423 ◽  
Author(s):  
KIYOSHI SHIBATA ◽  
SADAYOSHI SATSUMABAYASHI ◽  
HIROSHI SANO ◽  
KANKI KOMIYAMA ◽  
AKIRA NAKAGAWA ◽  
...  
Keyword(s):  
Chemical Modification ◽  
Antitumor Activities ◽  
Herbimycin A ◽  
Derivatives Of

The Alkyl Derivatives of Halogen Phenols and their Bactericidal Action. II. Bromophenols

1933 ◽  
Vol 55 (11) ◽  
pp. 4657-4662 ◽  
Author(s):  
Emil Klarmann ◽  
Louis W. Gates ◽  
Vladimir A. Shternov ◽  
Philip H. Cox
Keyword(s):  
Bactericidal Action ◽  
Alkyl Derivatives ◽  
Derivatives Of

570. Compounds of potential pharmacological interest. Part IV. Aryl and alkyl derivatives of 1-aminoindane

1956 ◽  
pp. 2928 ◽  
Author(s):  
J. A. Barltrop ◽  
R. M. Acheson ◽  
P. G. Philpott ◽  
K. E. MacPhee ◽  
J. S. Hunt
Keyword(s):  
Alkyl Derivatives ◽  
Pharmacological Interest ◽  
Derivatives Of
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